Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Zvi Cramer"'
Autor:
Ning Li, Qin Zhu, Yuhua Tian, Kyung Jin Ahn, Xin Wang, Zvi Cramer, Justine Jou, Ian W. Folkert, Pengfei Yu, Stephanie Adams-Tzivelekidis, Priyanka Sehgal, Najia N. Mahmoud, Cary B. Aarons, Robert E. Roses, Andrei Thomas-Tikhonenko, Emma E. Furth, Ben Z. Stanger, Anil Rustgi, Malay Haldar, Bryson W. Katona, Kai Tan, Christopher J. Lengner
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract The initiation and progression of cancer are intricately linked to the tumor microenvironment (TME). Understanding the function of specific cancer-TME interactions poses a major challenge due in part to the complexity of the in vivo microenv
Externí odkaz:
https://doaj.org/article/27a70ad4c8a74c5881020e751a7a5388
Autor:
Young-Jun Choi, Melissa S. Kim, Joshua H. Rhoades, Nicolette M. Johnson, Corbett T. Berry, Sarah Root, Qijun Chen, Yuhua Tian, Rafael J. Fernandez, III, Zvi Cramer, Stephanie Adams-Tzivelekidis, Ning Li, F. Brad Johnson, Christopher J. Lengner
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 16, Iss 3, Pp 451-472 (2023)
Background & Aims: Dyskeratosis congenita (DC) is a telomere biology disorder caused primarily by mutations in the DKC1 gene. Patients with DC and related telomeropathies resulting from premature telomere dysfunction experience multiorgan failure. In
Externí odkaz:
https://doaj.org/article/097aee7b209740a1bf70038743eb0b74
Autor:
Qu Deng, Ramakrishnan Natesan, Florencia Cidre-Aranaz, Shehbeel Arif, Ying Liu, Reyaz ur Rasool, Pei Wang, Erick Mitchell-Velasquez, Chandan Kanta Das, Endrit Vinca, Zvi Cramer, Patrick J. Grohar, Margaret Chou, Chandan Kumar-Sinha, Kristy Weber, T.S. Karin Eisinger-Mathason, Nicolas Grillet, Thomas Grünewald, Irfan A. Asangani
Publikováno v:
Cell Reports, Vol 39, Iss 11, Pp 110971- (2022)
Summary: Ewing sarcoma (EwS) is a highly aggressive tumor of bone and soft tissues that mostly affects children and adolescents. The pathognomonic oncofusion EWSR1::FLI1 transcription factor drives EwS by orchestrating an oncogenic transcription prog
Externí odkaz:
https://doaj.org/article/28e40682ce2f41f69b105d59455a86a7
Autor:
Oxana Dmitrieva-Posocco, Andrea C. Wong, Patrick Lundgren, Aleksandra M. Golos, Hélène C. Descamps, Lenka Dohnalová, Zvi Cramer, Yuhua Tian, Brian Yueh, Onur Eskiocak, Gabor Egervari, Yemin Lan, Jinping Liu, Jiaxin Fan, Jihee Kim, Bhoomi Madhu, Kai Markus Schneider, Svetlana Khoziainova, Natalia Andreeva, Qiaohong Wang, Ning Li, Emma E. Furth, Will Bailis, Judith R. Kelsen, Kathryn E. Hamilton, Klaus H. Kaestner, Shelley L. Berger, Jonathan A. Epstein, Rajan Jain, Mingyao Li, Semir Beyaz, Christopher J. Lengner, Bryson W. Katona, Sergei I. Grivennikov, Christoph A. Thaiss, Maayan Levy
Publikováno v:
Nature. 605:160-165
Colorectal cancer (CRC) is among the most frequent forms of cancer, and new strategies for its prevention and therapy are urgently needed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::492ecc9017182fde1fc4a4f14300f671
https://doi.org/10.1038/s41586-022-04649-6
https://doi.org/10.1038/s41586-022-04649-6
Autor:
Ning Li, Qin Zhu, Yuhua Tian, Kyung Jin Ahn, Xin Wang, Zvi Cramer, Ian W. Folkert, Pengfei Yu, Justine Jou, Stephanie Adams-Tzivelekidis, Priyanka Sehgal, Najia N. Mahmoud, Cary B. Aarons, Robert E. Roses, Andrei Thomas-Tikhonenko, Emma E. Furth, Ben Z. Stanger, Anil Rustgi, Malay Haldar, Bryson W. Katona, Kai Tan, Christopher J. Lengner
SummaryThe initiation and progression of cancer are inextricably linked to the tumor microenvironment (TME). Understanding the function of specific cancer-TME interactions poses a major challenge due in part to the complexity of the in vivo microenvi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6ef31e3f6c1fd48e3f5c0fe8a6e7b68
https://doi.org/10.1101/2022.09.13.506996
https://doi.org/10.1101/2022.09.13.506996
Autor:
Nicolette M Johnson, Louis R Parham, Jeeyoon Na, Keara E Monaghan, Hannah M Kolev, Alena Klochkova, Melissa S Kim, Charles H Danan, Zvi Cramer, Lauren A Simon, Kaitlyn E Naughton, Stephanie Adams‐Tzivelekidis, Yuhua Tian, Patrick A Williams, N Adrian Leu, Simone Sidoli, Kelly A Whelan, Ning Li, Christopher J Lengner, Kathryn E Hamilton
Publikováno v:
EMBO reports. 23(11)
The intestinal epithelium exhibits a rapid and efficient regenerative response to injury. Emerging evidence supports a model where plasticity of differentiated cells, particularly those in the secretory lineages, contributes to epithelial regeneratio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7e4cf4f73df5c7fe01b5854c0e32bc3
https://pubmed.ncbi.nlm.nih.gov/36120829
https://pubmed.ncbi.nlm.nih.gov/36120829
Autor:
Yuhua Tian, Xin Wang, Zvi Cramer, Joshua Rhoades, Katrina N. Estep, Xianghui Ma, Stephanie Adams Tzivelekidis, Bryson W Katona, F Brad Johnson, Zhengquan Yu, Mario Andres Blanco, Christopher Lengner, Ning Li
Colorectal cancer (CRC) is a leading cause of cancer-related deaths globally, with the majority of cases initiated by inactivation of the APC tumor suppressor. This results in the constitutive transcriptional activation of the canonical WNT signal tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::323fedb8ecb32d3a33efc381510be6f8
https://doi.org/10.1101/2022.07.26.501557
https://doi.org/10.1101/2022.07.26.501557
Autor:
Kelly Zullo, Rachel Cohen, Wenjie Wei, Nicole M Maloney, Karl Herbine, Xin Wang, Zvi Cramer, Li-Yin Hung, Christopher F. Pastore, Christopher J. Lengner, De’Broski R. Herbert, Ma Somsouk, Noam A. Cohen, Bonnie Douglas, Yun Wei, Yingbiao Ji, Michael H Kohanski
Publikováno v:
Scand J Gastroenterol
Aim: Recovery of damaged mucosal surfaces following inflammatory insult requires diverse regenerative mechanisms that remain poorly defined. Previously, we demonstrated that the reparative actions of Trefoil Factor 3 (TFF3) depend upon the enigmatic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37d669e3936df36cee20b93c9754aa26
https://doi.org/10.1080/00365521.2021.1917650
https://doi.org/10.1080/00365521.2021.1917650
Autor:
Christopher J. Lengner, Corbett T. Berry, Joshua H. Rhoades, Stephanie Adams-Tzivelekidis, Zvi Cramer, F. Brad Johnson, Qijun Chen, Youngjun Choi, Nicolette M. Johnson, Melissa S. Kim, Sarah Root, Rafael Fernandez, Yuhua Tian, Ning Li
Patients with dyskeratosis congenita (DC) and related telomeropathies resulting from premature telomere dysfunction suffer from multi-organ failure. In the liver, DC patients present with nodular hyperplasia, steatosis, inflammation, and cirrhosis. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eabf41108c7a36495a0b9a59caa39c65
https://doi.org/10.1101/2021.11.19.469258
https://doi.org/10.1101/2021.11.19.469258
Autor:
Qu Deng, Ramakrishnan Natesan, Florencia Cidre-Aranaz, Shehbeel Arif, Ying Liu, Reyaz ur Rasool, Pei Wang, Erick Mitchell-Velasquez, Chandan Kanta Das, Endrit Vinca, Zvi Cramer, Patrick J. Grohar, Margaret Chou, Chandan Kumar-Sinha, Kristy Weber, T.S. Karin Eisinger-Mathason, Nicolas Grillet, Thomas G.P. Grünewald, Irfan A. Asangani
Publikováno v:
Cell reports. 39(11)
Ewing sarcoma (EwS) is a highly aggressive tumor of bone and soft tissues that mostly affects children and adolescents. The pathognomonic oncofusion EWSR1::FLI1 transcription factor drives EwS by orchestrating an oncogenic transcription program throu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38d54b815d1ef9e26b11df9d43f527a0
https://pubmed.ncbi.nlm.nih.gov/35705030
https://pubmed.ncbi.nlm.nih.gov/35705030