Zobrazeno 1 - 10
of 798
pro vyhledávání: '"Zvi, Laron"'
Autor:
Haim Werner, Zvi Laron
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
The growth hormone (GH)-insulin-like growth factor-1 (IGF1) signaling pathway emerged in recent years as a key determinant of aging and longevity. Disruption of this network in different animal species, including flies, nematodes and mouse, was consi
Externí odkaz:
https://doaj.org/article/87ae8de496ce4aa290e5650019afed85
Publikováno v:
JCRPE, Vol 15, Iss 1, Pp 42-45 (2023)
INTRODUCTION: To determine the accuracy of adult height prediction in children with constitutional tall stature. METHODS: The medical records of 138 non-syndromatic prepubertal and early pubertal children (52 male, 86 female) with a height of ≥90t
Externí odkaz:
https://doaj.org/article/3ba97dd5f4cb494d8c072dc7288387bd
Publikováno v:
Children, Vol 11, Iss 2, p 142 (2024)
Background: The impact of the COVID-19 pandemic on the incidence rate of childhood type 1 diabetes (T1D) is controversial. Our aim was to analyze the incidence of new-onset T1D among children aged 0–17 before and during the COVID-19 pandemic in Isr
Externí odkaz:
https://doaj.org/article/71828e1ef23b484185cb48daa795b015
Autor:
Zvi Laron
Publikováno v:
Children, Vol 10, Iss 11, p 1757 (2023)
As the Section Editor-in-Chief, it is my pleasure to introduce the new section of Children devoted to pediatric endocrinology [...]
Externí odkaz:
https://doaj.org/article/51818cfd1bb847d186d4dc448b713781
Publikováno v:
Cells, Vol 11, Iss 20, p 3260 (2022)
The growth hormone (GH)–insulin-like growth factor-1 (IGF1) signaling pathway plays a major role in orchestrating cellular interactions, metabolism, growth and aging. Studies from worms to mice showed that downregulated activity of the GH/IGF1 path
Externí odkaz:
https://doaj.org/article/26c96e13378b490baa8aab386580619a
Autor:
Laris Achlaug, Lina Somri-Gannam, Shilhav Meisel-Sharon, Rive Sarfstein, Manisha Dixit, Shoshana Yakar, Mordechai Hallak, Zvi Laron, Haim Werner, Ilan Bruchim
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
The insulin-like growth factors (IGF) are important players in the development of gynecological malignancies, including epithelial ovarian cancer (EOC). The identification of biomarkers that can help in the diagnosis and scoring of EOC patients is of
Externí odkaz:
https://doaj.org/article/1afbe2b029f3461694ba8b14108ce8cf
Identification of UDP-Glucuronosyltransferase 2B15 (UGT2B15) as a Target for IGF1 and Insulin Action
Autor:
Rive Sarfstein, Karthik Nagaraj, Shivang Parikh, Carmit Levy, Zvi Laron, Dafna Benayahu, Haim Werner
Publikováno v:
Cells, Vol 11, Iss 10, p 1627 (2022)
Normal growth and development in mammals are tightly controlled by numerous genetic factors and metabolic conditions. The growth hormone (GH)-insulin-like growth factor-1 (IGF1) hormonal axis is a key player in the regulation of these processes. Dysr
Externí odkaz:
https://doaj.org/article/849f6f5318a646e0bf37f3ee2029a558
Autor:
Rand Shibel, Rive Sarfstein, Karthik Nagaraj, Lena Lapkina-Gendler, Zvi Laron, Manisha Dixit, Shoshana Yakar, Haim Werner
Publikováno v:
Cells, Vol 10, Iss 6, p 1483 (2021)
Endometrial cancer is the most common gynecologic malignancy in Western countries. The insulin-like growth factor-1 (IGF1) axis has an important role in endometrial cancer biology and emerged as a promising therapeutic target in oncology. However, th
Externí odkaz:
https://doaj.org/article/3d5acbacd8e84b5ebeb88f5e8d8ed1f4
Publikováno v:
Biomolecules, Vol 11, Iss 4, p 531 (2021)
Insulin (InsR) and insulin-like growth factor-1 (IGF1R) receptors mediate the metabolic and growth-promoting actions of insulin and IGF1/IGF2, respectively. Evidence accumulated in recent years indicates that, in addition to their typical cell-surfac
Externí odkaz:
https://doaj.org/article/55521504018a41069bcfa9f8c2169fde
Autor:
Lotem Goldberg, Zvi Laron, Liora Kornreich, Oded Scheuerman, Hadassa Goldberg-Stern, Dror Kraus
Publikováno v:
Hormone Research in Paediatrics. 95:286-290
Objective: The aim of the study was to describe focal epilepsy in patients with Laron syndrome (LS). Methods: Data were retrieved from medical records of a single-center cohort of 75 patients with LS. Results: We describe for the first time 4 patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42b29258888094e074666fcfdb598a70
https://doi.org/10.1159/000524350
https://doi.org/10.1159/000524350