Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Zuzana Závadová"'
Publikováno v:
British Journal of Cancer
Tumour-associated protein carbonic anhydrase IX (CA IX) has two major forms. One is a cell-associated, transmembrane protein seen on Western blots as a twin band of 54/58 kDa, expressed in gastric mucosa and in several types of cancer. The other is a
Autor:
Seppo Parkkila, Zuzana Závadová, Marta Ortova Gut, Jan Svoboda, Silvia Pastorekova, Ivan Horak, Zdeòka Vernerová, Jaromir Pastorek, Klaus-Peter Knobeloch, Bertram Wiedenmann, Michael Höcker, Jan Zavada, Adriana Gibadulinova, Elvira Rohde, Tuomo J. Karttunen
Publikováno v:
Gastroenterology. 123:1889-1903
Background & Aims: Carbonic anhydrase (CA) IX is a highly active enzyme with adhesion capacity that is functionally implicated in acid-base balance and intercellular communication. It is normally present in basolateral membranes of gastrointestinal e
Publikováno v:
British Journal of Cancer
MN/CA IX is a cell surface protein, strongly associated with several types of human carcinomas. It exerts activity of carbonic anhydrase and capacity of binding to cell surface receptors. In the present work, we used affinity purified MN/CA IX protei
Autor:
Jan Zavada, Ondrej Machon, Jaromir Pastorek, Zuzana Závadová, L. Kutinová, R. Opavsky, Sarka Nemeckova
Publikováno v:
International journal of oncology. 10(4)
The MN protein is associated with certain human carcinomas, but absent in most normal tissues. It is a transmembrane protein; its extracellular part contains a domain homologous with carbonic anhydrases (CAs) and a proteoglycan-like region. In the pr
Publikováno v:
Neoplasma. 56(4)
We investigated the expression of cell-associated CAIX protein in histological sections of the transitional cell carcinoma (TCC) of the urinary tract and of the soluble form of CAIX (s-CAIX) shed by the tumor into the serum and urine of TCC patients.
Autor:
Zuzana Závadová, Jan Zavada
Publikováno v:
Oncology reports. 13(5)
Expression of CA IX is normally restricted to the mucosa of alimentary tract, but on the other hand, it takes place in a high percentage of human cancers derived from tissues which are normally CA IX-negative. It is a transmembrane protein with two e
Autor:
Zuzana Závadová, Jan Zavada, Stefan Kaluz, Eva Závodská, Milota Kaluzová, Antony C. Willis, Silvia Pastorekova, Fedor Čiampor, Jaromir Pastorek, Lucia Reiserová
Publikováno v:
Virology. 257(1)
In this study we elucidated the molecular character of MaTu-MX, previously described as an unusual transmissible agent. Amino acid sequencing of peptides generated from a 58-kDa MX-related protein purified from MaTu human carcinoma cells allowed us t
Publikováno v:
Virology. 187(2)
MaTu is a quasi-viral agent presumably derived from a human mammary tumor. In some respects it resembles classical viruses and in some the “slow viruses,” and in others it is different from both. Using monoclonal antibodies (Mabs), we showed that
Publikováno v:
Virology. 127:345-360
Vesicular stomatitis virus (VSV) selectively assembled proteins from human cells into progeny virions. These proteins can be surface labeled before infection with 125I, and when purified virus was examined by sodium dodecyl sulfate (SDS)-polyacrylami
Publikováno v:
International Journal of Cancer. 34:91-94
A mouse hybridoma cell line IIB9, secreting IgG2b antibody specific for a HeLa cell antigen, was obtained by fusion of a mouse myeloma cell line with spleen cells from mice immunized with purified VSV tsO45 mutant (defective in assembly of G protein)