Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Zuzana Paračková"'
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Patients with STAT1 gain-of-function (GOF) mutations suffer from an inborn error of immunity hallmarked by chronic mucocutaneous candidiasis (CMC). The pathogenesis behind this complex and heterogeneous disease is still incompletely understood. Beyon
Externí odkaz:
https://doaj.org/article/ff55e25e2d0344048322da674f0ed1b3
Autor:
Adam Klocperk, Zuzana Parackova, Jitka Dissou, Hana Malcova, Petr Pavlicek, Tomas Vymazal, Pavla Dolezalova, Anna Sediva
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
We report a case of an 8-year-old girl who underwent a SARS-CoV-2 infection manifesting with atypical symptoms spearheaded by abdominal discomfort and systemic inflammation and partially mimicking hemophagocytic lymphohistiocytosis (HLH) or macrophag
Externí odkaz:
https://doaj.org/article/db709ac1c28f4ee5b32e9c1c2bfc464d
Autor:
Adam Klocperk, Zuzana Paračková, Markéta Bloomfield, Michal Rataj, Jan Pokorný, Susanne Unger, Klaus Warnatz, Anna Šedivá
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
DiGeorge syndrome is an immunodeficiency characterized by thymic dysplasia resulting in T cell lymphopenia. Most patients suffer from increased susceptibility to infections and heightened prevalence of autoimmune disorders, such as autoimmune thrombo
Externí odkaz:
https://doaj.org/article/17b08f0a4c7043ab9f9316b0e975da5d
Autor:
Adam Klocperk, Marketa Bloomfield, Zuzana Parackova, Ludovic Aillot, Jiri Fremuth, Lumir Sasek, Jan David, Filip Fencl, Aneta Skotnicova, Katerina Rejlova, Martin Magner, Ondrej Hrusak, Anna Sediva
Publikováno v:
Molecular and Cellular Pediatrics, Vol 10, Iss 1, Pp 1-8 (2023)
Abstract Background Multisystem inflammatory syndrome in children associated with COVID-19 (MIS-C) is a late complication of pediatric COVID-19, which follows weeks after the original SARS-CoV-2 infection, regardless of its severity. It is characteri
Externí odkaz:
https://doaj.org/article/f4b3704c1d504e8e8d58f03fbe2f9fa3
Autor:
Adriana A. de Jesus, Guibin Chen, Dan Yang, Tomas Brdicka, Natasha M. Ruth, David Bennin, Dita Cebecauerova, Hana Malcova, Helen Freeman, Neil Martin, Karel Svojgr, Murray H. Passo, Farzana Bhuyan, Sara Alehashemi, Andre T. Rastegar, Katsiaryna Uss, Lela Kardava, Bernadette Marrero, Iris Duric, Ebun Omoyinmi, Petra Peldova, Chyi-Chia Richard Lee, David E. Kleiner, Colleen M. Hadigan, Stephen M. Hewitt, Stefania Pittaluga, Carmelo Carmona-Rivera, Katherine R. Calvo, Nirali Shah, Miroslava Balascakova, Danielle L. Fink, Radana Kotalova, Zuzana Parackova, Lucie Peterkova, Daniela Kuzilkova, Vit Campr, Lucie Sramkova, Angelique Biancotto, Stephen R. Brooks, Cameron Manes, Eric Meffre, Rebecca L. Harper, Hyesun Kuehn, Mariana J. Kaplan, Paul Brogan, Sergio D. Rosenzweig, Melinda Merchant, Zuoming Deng, Anna Huttenlocher, Susan L. Moir, Douglas B. Kuhns, Manfred Boehm, Karolina Skvarova Kramarzova, Raphaela Goldbach-Mansky
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Neutrophilic inflammation is a hallmark of many monogenic autoinflammatory diseases. Here the authors report a case series of three unrelated boys with perinatal-onset of neutrophilic cutaneous small vessel vasculitis and systemic inflammation, and i
Externí odkaz:
https://doaj.org/article/ae467ac9fc384475ae6d8259f8ad7971
Autor:
Zuzana Parackova, Irena Zentsova, Marketa Bloomfield, Adam Klocperk, Rudolf Horvath, Hana Malcova, Dita Cebecauerova, Anna Sediva
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionJuvenile idiopathic arthritis (JIA), a clinically variable disease characterized by autoimmune arthritis, affects children, and its immunopathology remains elusive. Alterations in neutrophil biology play an important role in this disease.
Externí odkaz:
https://doaj.org/article/3c1ff646c020478199aeb355809d1dc2
Autor:
Milan Reinis, Zuzana Paračková, Romana Mikyšková, Jana Bieblová, Elżbieta Pajtasz-Piasecka, Veronika Vlkova, Marie Indrová, Joanna Rossowska, Jana Símová
Publikováno v:
Journal of Leukocyte Biology. 95:743-753
MDSCs represent one of the key players mediating immunosuppression. These cells accumulate in the TME, lymphoid organs, and blood during tumor growth. Their mobilization was also reported after CY therapy. DNMTi 5AC has been intensively studied as an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58905e699b9c161030b8fc5848e0c2bc
https://doi.org/10.1189/jlb.0813435
https://doi.org/10.1189/jlb.0813435
Autor:
Zuzana Parackova, Irena Zentsova, Hana Malcova, Dita Cebecauerova, Anna Sediva, Rudolf Horvath
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
ObjectivePosttranslational modifications (PTMs) of proteins are crucial for regulating various biological processes. However, protein alteration via PTMs, and consequently, the creation of new epitopes, can induce abnormal autoimmune responses in pre
Externí odkaz:
https://doaj.org/article/ac7986ddf6764a2eb0a759c64e14bd71
Autor:
Adam Klocperk, Jana Vcelakova, Petra Vrabcova, Irena Zentsova, Lenka Petruzelkova, Zdenek Sumnik, Stepanka Pruhova, Anna Sediva, Zuzana Parackova
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Type 1 diabetes (T1D) is an autoimmune disorder with unambiguous involvement of both innate and adaptive immune mechanisms in the destruction of pancreatic beta cells. Recent evidence demonstrated that neutrophils infiltrate the pancreas prior to dis
Externí odkaz:
https://doaj.org/article/a169e107ee2647559c422730bc83fbee
Autor:
Zuzana Parackova, Irena Zentsova, Petra Vrabcova, Adam Klocperk, Zdenek Sumnik, Stepanka Pruhova, Lenka Petruzelkova, Robert Hasler, Anna Sediva
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Neutrophils releasing neutrophil extracellular traps (NETs) infiltrate the pancreas prior to type 1 diabetes (T1D) onset; however, the precise nature of their contribution to disease remains poorly defined. To examine how NETs affect immune functions
Externí odkaz:
https://doaj.org/article/5333061925c045c182ea366222199c06