Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Zuzana Kudlickova"'
Publikováno v:
Molecules, Vol 24, Iss 18, p 3347 (2019)
Performing solution-phase oximation reactions with hydroxylamine hydrochloride (NH2OH·HCl) carries significant risk, especially in aqueous solutions. In the present study, four N-substituted indole-3-carboxaldehyde oximes were prepared from the corr
Externí odkaz:
https://doaj.org/article/dc57c909f44542ec91aae9ff32b8d406
Autor:
Maria Gazdova, Radka Michalkova, Martin Kello, Maria Vilkova, Zuzana Kudlickova, Janette Baloghova, Ladislav Mirossay, Jan Mojzis
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 20, p 12266 (2022)
This study was focused on investigating the antiproliferative effects of chalcone hybrids in melanoma cancer cells. Among seven chalcone hybrids, the chalcone-acridine hybrid 1C was the most potent and was selected for further antiproliferative mecha
Externí odkaz:
https://doaj.org/article/d9460624bc2c47a4b76a9623fe4ca2f0
Autor:
Radka Michalkova, Martin Kello, Zuzana Kudlickova, Maria Gazdova, Ladislav Mirossay, Gabriela Mojzisova, Jan Mojzis
Publikováno v:
Pharmaceutics, Vol 14, Iss 3, p 503 (2022)
Although new chemotherapy significantly increased the survival of breast cancer (BC) patients, the use of these drugs is often associated with serious toxicity. The discovery of novel anticancer agents for BC therapy is expected. This study was condu
Externí odkaz:
https://doaj.org/article/4ee940a16baa47fabf8e4f3b74d020e1
Publikováno v:
Molecules, Vol 26, Iss 5, p 1356 (2021)
Over the past decades, natural products have emerged as promising agents with multiple biological activities. Many studies suggest the antioxidant, antiangiogenic, antiproliferative and anticancer effects of chalcones and their derivatives. Based on
Externí odkaz:
https://doaj.org/article/04e2c4b9cf224f669333cc5cc116b010
Autor:
Monika Garberová, Zuzana Kudličková, Radka Michalková, Monika Tvrdoňová, Danica Sabolová, Slávka Bekešová, Michal Gramblička, Ján Mojžiš, Mária Vilková
Publikováno v:
Molecules, Vol 29, Iss 14, p 3387 (2024)
This study focuses on the synthesis and structural characterization of new compounds that integrate thiazolidine-2,4-dione, acridine moiety, and an acetamide linker, aiming to leverage the synergistic effects of these pharmacophores for enhanced ther
Externí odkaz:
https://doaj.org/article/338bd1247f564816bfc5ddb0335c0bb4
Publikováno v:
Green Chemistry Letters and Reviews, Vol 15, Iss 2, Pp 474-482 (2022)
An efficient eco-friendly one-step mechanochemical synthesis of indole hybrid chalcones via the Claisen–Schmidt condensation of 1-methylindole-3-carboxaldehyde with various substituted acetophenones is described using liquid assisted grinding in a
Externí odkaz:
https://doaj.org/article/6531480d19e54608a15c596d7d221f44
Autor:
Zuzana Kudličková, Radka Michalková, Aneta Salayová, Marián Ksiažek, Mária Vilková, Slávka Bekešová, Ján Mojžiš
Publikováno v:
Molecules, Vol 28, Iss 18, p 6583 (2023)
The synthesis, anticancer, and antioxidant activities of a series of indole-derived hybrid chalcones are reported here. First, using the well-known Claisen–Schmidt condensation method, a set of 29 chalcones has been designed, synthesized, and conse
Externí odkaz:
https://doaj.org/article/ecd0152545834cb6b43f4adf1fccc6ef
Autor:
Monika Garberová, Ivan Potočňák, Monika Tvrdoňová, Monika Majirská, Martina Bago-Pilátová, Slávka Bekešová, Andrej Kováč, Peter Takáč, Krutika Khiratkar, Zuzana Kudličková, Ján Elečko, Mária Vilková
Publikováno v:
Molecules, Vol 28, Iss 18, p 6616 (2023)
Derivatives combining acridine, pyrrole, and thiazolidine rings have emerged as promising candidates in the field of antitumor drug discovery. This paper aims to highlight the importance of these three structural motifs in developing potent and selec
Externí odkaz:
https://doaj.org/article/a810e3b529f2457db87526c75a782354