Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Zuzana Cierna"'
Publikováno v:
Urology Case Reports, Vol 46, Iss , Pp 102304- (2023)
A 28-year-old male with bilateral testicular seminoma underwent bilateral orchiectomy and radiation therapy of the retroperitoneum. After 17 years, he had a retroperitoneal tumor detected, which was removed 7 years later at age 52 because of its prog
Externí odkaz:
https://doaj.org/article/f732787c13414c8e9f2822f7c7734701
Autor:
Michal Mego, Barbora Vlkova, Gabriel Minarik, Zuzana Cierna, Marian Karaba, Juraj Benca, Tatiana Sedlackova, Dana Cholujova, Paulina Gronesova, Katarina Kalavska, Daniel Pindak, Jozef Mardiak, Peter Celec
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundCirculating tumor cells (CTCs) contribute to the metastatic cascade and represent an independent survival predictor in breast cancer (BC) patients. Vitamin D has pleiotropic effects, and its low concentrations are associated with breast can
Externí odkaz:
https://doaj.org/article/867b3ca3a243447a8a3e63865a0ced71
Autor:
Zuzana Cierna, Bozena Smolkova, Dana Cholujova, Paulina Gronesova, Svetlana Miklikova, Marina Cihova, Jana Plava, Michal Mego
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Programmed death ligand 1 (PD-L1) overexpression has been associated with poor clinical outcomes in several human cancers whose increased malignant behaviour might be related to PD-L1 mediated systemic immunological tolerance. This study aim
Externí odkaz:
https://doaj.org/article/0c8a61ac91ed49e2ab85bcac9794a1e9
Autor:
Zuzana Cierna, Vera Miskovska, Jan Roska, Dana Jurkovicova, Lucia Borszekova Pulzova, Zuzana Sestakova, Lenka Hurbanova, Katarina Machalekova, Michal Chovanec, Katarina Rejlekova, Daniela Svetlovska, Katarina Kalavska, Karol Kajo, Pavel Babal, Jozef Mardiak, Thomas A. Ward, Michal Mego, Miroslav Chovanec
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-12 (2020)
Abstract Background Germ cell tumours (GCTs) represent a highly curable malignity as they respond well to cisplatin (CDDP)-based chemotherapy. Nevertheless, a small proportion of GCT patients relapse or do not respond to therapy. As this might be cau
Externí odkaz:
https://doaj.org/article/a1198c34116345488384869795332127
Autor:
Michal Chovanec, Zuzana Cierna, Viera Miskovska, Katarina Machalekova, Katarina Kalavska, Katarina Rejlekova, Daniela Svetlovska, Dusan Macak, Stanislav Spanik, Karol Kajo, Pavel Babal, Michal Mego, Jozef Mardiak
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-10 (2018)
Abstract Background WNT/βcatenin (WNTβ) pathway is activated in early stages of embryonic development. We aimed to evaluate the significance of βcatenin in germ cell tumors (GCTs) and explore associations with the inflamed environment. Methods Sur
Externí odkaz:
https://doaj.org/article/e2bedfd776a24a93b149c36fc239cb18
Autor:
Lenka Kalinkova, Iveta Zmetakova, Bozena Smolkova, Gabriel Minarik, Tatiana Sedlackova, Viera Horvathova Kajabova, Zuzana Cierna, Michal Mego, Ivana Fridrichova
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-12 (2018)
Abstract Background In breast cancer (BC), deregulation of DNA methylation leads to aberrant expressions and functions of key regulatory genes. In our study, we investigated the relationship between the methylation profiles of genes associated with c
Externí odkaz:
https://doaj.org/article/40989d32722b4cc891bddd8ae68c0071
Autor:
Erika Durinikova, Zuzana Kozovska, Martina Poturnajova, Jana Plava, Zuzana Cierna, Andrea Babelova, Roman Bohovic, Silvia Schmidtova, Miroslav Tomas, Lucia Kucerova, Miroslava Matuskova
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-15 (2018)
Abstract Background Efficiency of colorectal carcinoma treatment by chemotherapy is diminished as the resistance develops over time in patients. The same holds true for 5-fluorouracil, the drug used in first line chemotherapy of colorectal carcinoma.
Externí odkaz:
https://doaj.org/article/326bf50d13734893a14359bc0eddf87a
Autor:
Silvia Schmidtova, Katarina Kalavska, Veronika Liskova, Jana Plava, Svetlana Miklikova, Lucia Kucerova, Miroslava Matuskova, Lucia Rojikova, Zuzana Cierna, Adriana Rogozea, Heiko Konig, Costantine Albany, Michal Mego, Michal Chovanec
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 8, p 4263 (2021)
The majority of patients with testicular germ cell tumors (GCTs) can be cured with cisplatin-based chemotherapy. However, for a subset of patients present with cisplatin-refractory disease, which confers a poor prognosis, the treatment options are li
Externí odkaz:
https://doaj.org/article/f36766710861418fba3321b46fa76f98
Autor:
Katarina Letkovska, Pavel Babal, Zuzana Cierna, Silvia Schmidtova, Veronika Liskova, Katarína Kalavska, Vera Miskovska, Samuel Horak, Katarina Rejlekova, Michal Chovanec, Jozef Mardiak, Pavel Janega, Michal Mego
Publikováno v:
Cancers, Vol 13, Iss 4, p 776 (2021)
Apoptosis is a strictly regulated process essential for preservation of tissue homeostasis. This study aimed to evaluate expression of apoptosis inducing factor (AIF) in testicular germ cell tumors (GCTs) and to correlate expression patterns with cli
Externí odkaz:
https://doaj.org/article/9d8b9b8d436f4c468f833766248fa86a
Autor:
Bozena Smolkova, Zuzana Cierna, Katarina Kalavska, Svetlana Miklikova, Jana Plava, Gabriel Minarik, Tatiana Sedlackova, Dana Cholujova, Paulina Gronesova, Marina Cihova, Karolina Majerova, Marian Karaba, Juraj Benca, Daniel Pindak, Jozef Mardiak, Michal Mego
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 24, p 9460 (2020)
Circulating tumor cells (CTCs) and the immune infiltration of tumors are closely related to clinical outcomes. This study aimed to verify the influence of stromal lymphocyte infiltration and the immune context of tumor microenvironment on the hematog
Externí odkaz:
https://doaj.org/article/57523391fcf44b2dacdf79b1a01b0146