Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Zuzana, Kyselova"'
Autor:
Milos V. Novotny, Yehia Mechref, Zuzana Kyselova, Sameera Ezzat, Iman Gouda, Mohamed Abdel-Hamid, Christopher A. Loffredo, Gregory Bascug, Lenka Goldman, Rency S. Varghese, Habtom W. Ressom, Radoslav Goldman
Purpose: Hepatocellular carcinoma (HCC) represents an increasing health problem in the United States. Serum α-fetoprotein, the currently used clinical marker, is elevated in only ∼60% of HCC patients; therefore, the identification of additional ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a4fb0c887eb0c7bd48ea612efe2d840
https://doi.org/10.1158/1078-0432.c.6517392
https://doi.org/10.1158/1078-0432.c.6517392
Autor:
Milos V. Novotny, Yehia Mechref, Zuzana Kyselova, Sameera Ezzat, Iman Gouda, Mohamed Abdel-Hamid, Christopher A. Loffredo, Gregory Bascug, Lenka Goldman, Rency S. Varghese, Habtom W. Ressom, Radoslav Goldman
Supplementary Data from Detection of Hepatocellular Carcinoma Using Glycomic Analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9f906639cabd8b4827d3ff01e98c8fb
https://doi.org/10.1158/1078-0432.22440012
https://doi.org/10.1158/1078-0432.22440012
Autor:
Milos V. Novotny, Habtom W. Ressom, Slavka Bekesova, Radoslav Goldman, Rency S. Varghese, Christopher A. Loffredo, Zuzana Kyselova, Mohamed Abdul Hamid, Yehia Mechref, Zhiqun Tang
Publikováno v:
Journal of Proteome Research. 9:104-112
Glycocylation represents the most complex and widespread post-translational modifications in human proteins. The variation of glycosylation is closely related to oncogenic transformation. Therefore, profiling of glycans detached from proteins is a pr
Autor:
Christopher A. Loffredo, Iman Gouda, Sameera Ezzat, Habtom W. Ressom, Milos V. Novotny, Radoslav Goldman, Gregory Bascug, Zuzana Kyselova, Rency S. Varghese, Yehia Mechref, Mohamed Abdel-Hamid, Lenka Goldman
Publikováno v:
Clinical Cancer Research. 15:1808-1813
Purpose: Hepatocellular carcinoma (HCC) represents an increasing health problem in the United States. Serum α-fetoprotein, the currently used clinical marker, is elevated in only ∼60% of HCC patients; therefore, the identification of additional ma
Autor:
Christopher A. Loffredo, Yanming An, Lenka Goldman, Steven K. Drake, Milos V. Novotny, Rency S. Varghese, Yehia Mechref, Mohamed Abdel-Hamid, Zuzana Kyselova, Habtom W. Ressom, Radoslav Goldman
Publikováno v:
Journal of Proteome Research. 7:603-610
This paper presents computational methods to analyze MALDI-TOF mass spectrometry data for quantitative comparison of peptides and glycans in serum. The methods are applied to identify candidate biomarkers in serum samples of 203 participants from Egy
Autor:
Yehia Mechref, David E. Clemmer, Ruwan T. Kurulugama, Zuzana Kyselova, Sarah T. Stokes, Radoslav Goldman, Vitara Pungpapong, Dragan Isailovic, Manolo D. Plasencia, Milos V. Novotny, Min Zhang, M. M. Gaye
Publikováno v:
Journal of proteome research. 11(2)
Altered branching and aberrant expression of N-linked glycans is known to be associated with disease states such as cancer. However, the complexity of determining such variations hinders the development of specific glycomic approaches for assessing d
Autor:
Zuzana, Kyselova
Publikováno v:
Interdisciplinary Toxicology
Cataract, the opacification of eye lens, is the leading cause of blindness worldwide. At present, the only remedy is surgical removal of the cataractous lens and substitution with a lens made of synthetic polymers. However, besides significant costs
Autor:
Jan, Klimas, Jana, Kmecova, Stanislava, Jankyova, Diana, Yaghi, Elena, Priesolova, Zuzana, Kyselova, Peter, Musil, Peter, Ochodnicky, Peter, Krenek, Jan, Kyselovic, Stefan, Matyas
Publikováno v:
Phytotherapy research : PTR. 24(7)
We studied whether Pycnogenol (PYC) may attenuate the development of experimental streptozotocin-induced diabetic cardiomyopathy in rat. In addition, we aimed to study whether PYC affects cardiac oxidative stress and the protein expression of reactiv
Autor:
Lauren Schnaper, Pilsoo Kang, Lacey E. Dobrolecki, Zuzana Kyselova, Milos V. Novotny, Yehia Mechref, John A. Goetz, Robert J. Hickey, Linda H. Malkas, George W. Sledge
Publikováno v:
Clinical chemistry. 54(7)
Background: Glycosylated proteins play important roles in cell-to-cell interactions, immunosurveillance, and a variety of receptor-mediated and specific protein functions through a highly complex repertoire of glycan structures. Aberrant glycosylatio
Autor:
Radoslav Goldman, Habtom W. Ressom, Rency S. Varghese, Yehia Mechref, Zuzana Kyselova, Mohamed Abdel-Hamid, Christopher A. Loffredo, Milos V. Novotny, Lenka Goldman
Publikováno v:
Pacific Symposium on Biocomputing
Scopus-Elsevier
Scopus-Elsevier
We present a computational framework for analysis of MALDI-TOF mass spectrometry data to enable quantitative comparison of glycans in serum. The proposed framework enables a systematic selection of glycan structures that have good generalization capa