Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Zuyin Yu"'
RNA N6-methyladenosine modification-based biomarkers for absorbed ionizing radiation dose estimation
Autor:
Hongxia Chen, Xi Zhao, Wei Yang, Qi Zhang, Rongjiao Hao, Siao Jiang, Huihui Han, Zuyin Yu, Shuang Xing, Changjiang Feng, Qianqian Wang, Hao Lu, Yuanfeng Li, Cheng Quan, Yiming Lu, Gangqiao Zhou
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Radiation triage and biological dosimetry are critical for the medical management of massive potentially exposed individuals following radiological accidents. Here, we performed a genome-wide screening of radiation-responding mRNAs, whose N6
Externí odkaz:
https://doaj.org/article/9b353cd1660d440ebdcb037769508c64
Autor:
Nan Chen, Renxi Wang, Wanlu Zhu, Xiangjun Hao, Jing Wang, Guojiang Chen, ChunXia Qiao, Xinying Li, Chenghua Liu, Beifen Shen, Jiannan Feng, Lihui Chai, Zuyin Yu, He Xiao
Publikováno v:
PLoS ONE, Vol 19, Iss 5, p e0302865 (2024)
Influenza A viruses (IAVs) continue to pose a huge threat to public health, and their prevention and treatment remain major international issues. Neuraminidase (NA) is the second most abundant surface glycoprotein on influenza viruses, and antibodies
Externí odkaz:
https://doaj.org/article/7544374129ad40b1ba754f2da9e2b606
Autor:
Xuewen Zhang, Zizhi Qiao, Bo Guan, Fangming Wang, Xing Shen, Hui Shu, Yajun Shan, Yuwen Cong, Shuang Xing, Zuyin Yu
Publikováno v:
Molecules, Vol 29, Iss 4, p 816 (2024)
Ionizing radiation (IR)-induced hematopoietic injury has become a global concern in the past decade. The underlying cause of this condition is a compromised hematopoietic reserve, and this kind of hematopoietic injury could result in infection or ble
Externí odkaz:
https://doaj.org/article/fa41c618b05349f2ab490a60abdf44cb
Autor:
Jilu Zhang, Xun Wang, Renxi Wang, Guojiang Chen, Jing Wang, Jiannan Feng, Yan Li, Zuyin Yu, He Xiao
Publikováno v:
Biomedicines, Vol 11, Iss 3, p 949 (2023)
In this study, we test the therapeutic effects of rapamycin in a murine model of SLE-like experimental lupus nephritis induced by chronic graft-versus-host disease (cGVHD). Our results suggest that rapamycin treatment reduced autoantibody production,
Externí odkaz:
https://doaj.org/article/61f7d23c91d24d13a0e0c396bf2c96a8
Autor:
Hao Luan, Jinkun Yang, Yemei Wang, Xing Shen, Xuewen Zhang, Zizhi Qiao, Shuang Xing, Zuyin Yu
Publikováno v:
Molecules, Vol 28, Iss 4, p 1953 (2023)
Exposure to medium and high doses of ionizing radiation (IR) can induce long-term bone marrow (BM) suppression. We previously showed that recombinant human thrombopoietin (rhTPO) significantly promotes recovery from hematopoietic-acute radiation synd
Externí odkaz:
https://doaj.org/article/c1a9b3fc31844f0aa534ac6098444276
Autor:
Limei Wang, Chao Jia, Zuyin Yu, Xiaolan Liu, Liping Kang, Yue Cong, Yajun Shan, Zhenhu Zhao, Baiping Ma, Yuwen Cong
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51536 (2012)
BACKGROUND: Total steroidal saponins extracted from the rhizome of Paris polyphylla Sm. var. yunnanensis (TSSPs) have been widely used in China for the treatment of abnormal uterine bleeding. We previously studied the main active constituents of TSSP
Externí odkaz:
https://doaj.org/article/84916b9a42884155bcbf18400a0d7e1d
Publikováno v:
Clinical and Translational Imaging. 10:413-424
Autor:
Xiaolan Liu, Zuyin Yu, Zongchao Zuo, Yingying Tang, Wenting Zhang, Yuwen Cong, Limei Wang, Ya-Jun Shan, Renjun Peng
Publikováno v:
Free Radical Biology and Medicine. 153:1-11
In mass casualty events involving radiation exposure, there is a substantial unmet need for identifying and developing an orally bioavailable agent that can be used to protect the hematopoietic stem cell pool and regenerate hematopoiesis after radiat
Autor:
Li-Rong Yi, Renjun Peng, Cheng Zhang, Zongchao Zuo, Yuwen Cong, Limei Wang, Fan Bai, Zuyin Yu, Li Zhongtang, Ya-Jun Shan, Rifang Yang, Chao Yang
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 103:217-228
Purpose The risk of radiation exposure is considered to have increased in recent years. For convenience and simple administration, development of an effective orally administered radioprotective agent is highly desirable. The steroid 5-androstene-3β
Autor:
Ya-Jun Shan, Chao Yang, Hong-wei Tang, Renjun Peng, Ping-Kun Zhou, Limei Wang, Zuyin Yu, Yuwen Cong, Fan Bai
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 102:1577-1589
Purpose Oral mucositis is one of the most prevalent side effects in patients undergoing radiation therapy for head and neck cancers. Current therapeutic agents such as palifermin recombinant human keratinocyte growth factor and amifostine do not effi