Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Zutao Yu"'
Publikováno v:
Pharmaceuticals, Vol 16, Iss 2, p 244 (2023)
In a preliminary study, we synthesized a series of new PDK1/MEK dual inhibitors. Antitumor activity screening showed that Compound YZT exerts a strong inhibitory action in A549 cells. However, the specific mechanism of YZT against non-small cell lung
Externí odkaz:
https://doaj.org/article/e63b6aae63044a18bb73a4fb48ea60f5
Autor:
Rangru Liu, Zutao Yu, Zhuo Chen, Danqi Liu, Fengying Huang, Qianbin Li, Gaoyun Hu, Xinan Yi, Xi Li, Honghao Zhou, Zhaoqian Liu
Publikováno v:
PeerJ, Vol 8, p e9981 (2020)
Background A novel dual MEK/PDK1 inhibitor named 9za has been synthesized by our research team. Preliminary study showed that 9za possessed potent cytotoxicity and proapoptosis in non-small cell lung cancer (NSCLC) cells. Nevertheless, the precise un
Externí odkaz:
https://doaj.org/article/c541aaa1e8034672878d46f2fed420a0
Autor:
Yulei Wei, Ganesh N. Pandian, Zutao Yu, Tingting Zou, Yue Li, Jayant Darokar, Kaori Hashiya, Toshikazu Bando, Hiroshi Sugiyama
Publikováno v:
ACS Omega, Vol 3, Iss 3, Pp 3608-3616 (2018)
Externí odkaz:
https://doaj.org/article/90751ae2929c4afebaef7034c5ee24c0
Publikováno v:
Molecules, Vol 24, Iss 3, p 429 (2019)
A G-quadruplex (G4) is a well-known nucleic acid secondary structure comprising guanine-rich sequences, and has profound implications for various pharmacological and biological events, including cancers. Therefore, ligands interacting with G4s have a
Externí odkaz:
https://doaj.org/article/112ab41f0e1d48e4865d87e8e76958c8
Publikováno v:
Trends in Genetics. 39:15-30
G-quadruplexes (G4s) are non-canonical structures formed in guanine (G)-rich sequences through stacked G tetrads by Hoogsteen hydrogen bonding. Several studies have demonstrated the existence of G4s in the genome of various organisms, including human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9323e372d2073c5a25aeb582d476ae3c
https://doi.org/10.1016/j.tig.2022.10.006
https://doi.org/10.1016/j.tig.2022.10.006
Publikováno v:
Nucleic Acids in Medicinal Chemistry and Chemical Biology. :132-156
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed307374ed2a20de007700748509d1fd
https://doi.org/10.1002/9781119692799.ch5
https://doi.org/10.1002/9781119692799.ch5
Autor:
Soundhar Ramasamy, Vinodh J. Sahayasheela, Surbhi Sharma, Zutao Yu, Takuya Hidaka, Li Cai, Vaijayanthi Thangavel, Hiroshi Sugiyama, Ganesh N. Pandian
Publikováno v:
ACS Chemical Biology. 17(10):2704-2709
Nanopore direct RNA sequencing (dRNA-Seq) reads reveal RNA modifications through consistent error profiles specific to a modified nucleobase. However, a null data set is required to identify actual RNA modification-associated errors for distinguishin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::944d81fa07f45c9a6450814a7bf0b009
http://hdl.handle.net/2433/277273
http://hdl.handle.net/2433/277273
Autor:
Esain-Garcia, Isabel, Kirchner, Angie, Melidis, Larry, de Cesaris Araujo Tavares, Rafael, Dhir, Somdutta, Simeone, Angela, Zutao Yu, Madden, Sarah K., Hermann, Regina, Tannahill, David, Balasubramanian, Shankar
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 2/13/2024, Vol. 121 Issue 7, p1-9, 45p
Autor:
Vinodh J. Sahayasheela, Zutao Yu, Yuki Hirose, Ganesh N. Pandian, Toshikazu Bando, Hiroshi Sugiyama
Publikováno v:
Bulletin of the Chemical Society of Japan. 95:693-699
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e12c4a1d63d9d9439f4eb7d8185eeab6
https://doi.org/10.1246/bcsj.20210453
https://doi.org/10.1246/bcsj.20210453
Publikováno v:
Journal of Clinical Pharmacy and Therapeutics. 45:852-855
What is known and objective Vancomycin removal by dialysis uses methods that differ in type of dialysis membrane, dialysis fluxes and duration, ultrafiltration rate and Kt/Vurea (K = dialyser urea clearance, t = time on dialysis and V = total body wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5990f648de4b67d3cfd7d7fc2b00cb2d
https://doi.org/10.1111/jcpt.13181
https://doi.org/10.1111/jcpt.13181