Lack of Pharmacokinetic Interactions Between Cilomilast and Theophylline or Smoking in Healthy Volunteers

Autor: Dawn M. Webber, Zussman Barry D, J. Paul Schofield, Robert D. Murdoch

Publikováno v: The Journal of Clinical Pharmacology. 44:1046-1053

The pharmacokinetic profile of cilomilast (Ariflo®), a selective phosphodiesterase 4 (PDE4) inhibitor, was investigated in three separate studies. Two of these studies explored the drug interaction potential of cilomilast with the nonselective PDE i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7edd6c1c4de7a42a79ae8f07458c0785
https://doi.org/10.1177/0091270004266488

Paroxetine Does Not Affect the Cardiac Safety and Pharmacokinetics of Terfenadine in Healthy Adult Men

Autor: Daniel Everitt, Rickey C. Etheredge, Diane K. Jorkasky, David E. Martin, Zussman Barry D, Lisa J. Benincosa

Publikováno v: Journal of Clinical Psychopharmacology. 17:451-459

Potent CYP3A4 inhibitors such as ketoconazole can cause dangerous increases in plasma concentrations of the H-1 antagonist terfenadine. In light of recent reports that the selective serotonin re-uptake inhibitor antidepressants may be weak CYP3A4 inh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2db7c550a2b964237294691e008ea3a
https://doi.org/10.1097/00004714-199712000-00003

The relationship between paroxetine and the sparteine oxidation polymorphism

Autor: Søren H. Sindrup, Tim C G Tasker, Ann Allen, Zussman Barry D, Erik Skjelbo, Graham D Allen, Lars F. Gram, Kim Brøsen, Jesper Hallas, Steven M Cooper, Graham Mellows

Publikováno v: Sindrup, S H, Brøsen, K, Gram, L F, Hallas, J, Skjelbo, E, Allen, A, Allen, G D, Cooper, S M, Mellows, G, Tasker, T C G & Zussman, B D 1992, ' The relationship between paroxetine and the sparteine oxidation polymorphism ', Clinical Pharmacology & Therapeutics, vol. 51, no. 3, pp. 278-287 . https://doi.org/10.1038/clpt.1992.23

The relationship between the selective serotonin reuptake inhibitor paroxetine and the sparteine oxidation polymorphism was investigated in a combined single‐dose (30 mg) and steady‐state (30 mg/day for 2 weeks) study including a panel of nine ex

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24a23ffeab4b618369edbe8eb7d81040
https://pubmed.ncbi.nlm.nih.gov/1531950

Paroxetine Does Not Affect the Cardiac Safety and Pharmacokinetics of Terfenadine in Healthy Adult Men.

Autor: Martin, David E., Zussman, Barry D., Everitt, Daniel E., Benincosa, Lisa J., Etheredge, Rickey C., Jorkasky, Diane K.

Publikováno v: Journal of Clinical Psychopharmacology; Dec1997, p451-459, 9p

Lack of Pharmacokinetic Interactions Between Cilomilast and Theophylline or Smoking in Healthy Volunteers

Autor: Murdoch, Robert D., Zussman, Barry, Schofield, J. Paul, Webber, Dawn M.

Publikováno v: Journal of Clinical Pharmacology; September 2004, Vol. 44 Issue: 9 p1046-1053, 8p