Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Zurina Romay-Penabad"'
Autor:
Rohan Willis, Thomas C. R. McDonnell, Charis Pericleous, Emilio B. Gonzalez, Alvaro Schleh, Zurina Romay-Penabad, Ian P. Giles, Anisur Rahman
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Antiphospholipid syndrome (APS) is an autoimmune disorder in which autoantibodies cause clinical effects of vascular thrombosis and pregnancy morbidity. The only evidence-based treatments are anticoagulant medications such as warfarin and heparin. Th
Externí odkaz:
https://doaj.org/article/b1d23db02f4044e2816293b90112e7f5
Autor:
Thomas C. R. McDonnell, Rohan Willis, Charis Pericleous, Vera M. Ripoll, Ian P. Giles, David. A. Isenberg, Allan R. Brasier, Emilio B. Gonzalez, Elizabeth Papalardo, Zurina Romay-Penabad, Mohammad Jamaluddin, Yiannis Ioannou, Anisur Rahman
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
APS is an autoimmune disease in which antiphospholipid antibodies (aPL) cause vascular thrombosis and pregnancy morbidity. In patients with APS, aPL exert pathogenic actions by binding serum beta-2-glycoprotein I (β2GPI) via its N-terminal domain I
Externí odkaz:
https://doaj.org/article/5dbe595d033240e5b72049f6a3eda9b1
Autor:
Rohan Willis, Thomas C. R. McDonnell, Charis Pericleous, Emilio B. Gonzalez, Alvaro Schleh, Zurina Romay-Penabad, Ian P. Giles, Anisur Rahman
Publikováno v:
Frontiers in immunology. 13
Antiphospholipid syndrome (APS) is an autoimmune disorder in which autoantibodies cause clinical effects of vascular thrombosis and pregnancy morbidity. The only evidence-based treatments are anticoagulant medications such as warfarin and heparin. Th
Autor:
Allan R. Brasier, Ethel García-Latorre, Elba Reyes-Maldonado, Rajani Rudrangi, Premkumar Christadoss, Silvana Alfieri-Papalardo, Rohan Willis, Miri Blank, Zurina Romay-Penabad, Ana Laura Carrera-Marin, Emilio B. Gonzalez, Elizabeth Papalardo, Silvia S. Pierangeli
Publikováno v:
Arthritis & Rheumatology. 69:2052-2061
Objective:Both environmental and genetic factors are important in antiphospholipid antibody(aPL) development in antiphospholipid syndrome(APS). Currently, the only available data on predisposing genetic factors have been obtained from epidemiological
Autor:
Doruk Erkan, PJ Lane, Esther Rodriguez, Miao Qi, Maria Efthymiou, Maria Laura Bertolaccini, E. Bison, Tatsuya Atsumi, JoAnn Vega, D. Ware Branch, Laura Andreoli, Cecilia Beatrice Chighizola, Jason S. Knight, Savino Sciascia, Hannah Cohen, Zurina Romay-Penabad, Guilherme Ramires de Jesus, H. Michael Belmont, Vittorio Pengo, Amaia Ugarte, Danieli Andrade, Margarete Borges Galhardo Vendramini, Rohan Willis, I Mackie, Maria Angeles Aguirre, Steven Krillis, Michelle Petri, Paul R. Fortin, Ricard Cervera, Ecem Sevim, Lanlan Ji, Maria G Tektonidou
Publikováno v:
Journal of thrombosis and haemostasis : JTHREFERENCES. 17(12)
BACKGROUND Variability remains a challenge in lupus anticoagulant (LA) testing. OBJECTIVE To validate LA test performance between Antiphospholipid Syndrome Alliance for Clinical Trials and International Networking (APS ACTION) Core laboratories and e
Autor:
Praveen Jajoria, Elizabeth Papalardo, Jane E. Salmon, Grant Pierre, Amaris Castanon, DeCeulaer K, E. Nigel Harris, Anne E. Tebo, D. Ware Branch, Troy D. Jaskowski, Zurina Romay-Penabad, Rohan Willis, Emilio B. Gonzalez, Alvaro Schleh, Michelle Petri, Marta M. Guerra, Monica Smikle
Objectives We evaluate the performance characteristics of antiphosphatidylserine (anti-PS), antiphosphatidylinositol (anti-PI), and antiphospholipid mixture (APhL) enzyme-linked immunosorbent assays (ELISAs) compared with anticardiolipin (aCL) and an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f3f87a0de991846ad5caf44826132e1
https://europepmc.org/articles/PMC5889035/
https://europepmc.org/articles/PMC5889035/
Autor:
Rohan Willis, Charis Pericleous, Thomas McDonnell, Zurina Romay-Penabad, Elizabeth Papalardo, Anisur Rahman, Yiannis Ioannou, Ian Giles
Publikováno v:
Rheumatology. 56
Autor:
Alan M. Seif, Marius Teodorescu, Patricia Ruiz-Limon, Rohan Willis, Trisha M. Parekh, Terry A. McNearney, Elizabeth Papalardo, Luis M. Vilá, Graciela S. Alarcón, Rashmi Maganti, Shraddha Jatwani, Walter Binder, Zakera Shums, Zurina Romay-Penabad, Gerald McGwin, Prashanth Sunkureddi, Laura Aline Martinez-Martinez, John D. Reveille, Praveen Jajoria, Michael Tarantino, Ehtisham Akhter, Gary L. Norman, Michelle Petri, Jigna Liu, Silvia S. Pierangeli, Emilio B. Gonzalez, Hong Fang, Vijaya Murthy
Publikováno v:
Arthritis & Rheumatism. 65:3186-3193
Objective To examine the prevalence of isolated IgA anti–β2-glycoprotein I (anti-β2GPI) positivity and the association of these antibodies, and a subgroup that bind specifically to domain IV/V of β2GPI, with clinical manifestations of the antiph
Autor:
Zurina Romay-Penabad, Gracie Vargas, Maarten T. T. Pennings, Elizabeth Papalardo, Renan Aguilar-Valenzuela, Philip G. de Groot, Tuya Shilagard, Yong Gil Hwang, Rolf T. Urbanus, Ronald H. W. M. Derksen, Silvia S. Pierangeli
Publikováno v:
Blood. 117:1408-1414
Antiphospholipid (aPL)/anti-β2 glycoprotein I (anti-β2GPI) antibodies stimulates tissue factor (TF) expression within vasculature and in blood cells, thereby leading to increased thrombosis. Several cellular receptors have been proposed to mediate
Complement C5-inhibitor rEV576 (coversin) ameliorates in-vivo effects of antiphospholipid antibodies
Autor:
Allan R. Brasier, Zurina Romay-Penabad, Hannah Cohen, Emilio B. Gonzalez, Samuel J. Machin, A. L. Carrera Marin, W. Weston-Davies, Rohan Willis
Publikováno v:
Lupus. 23:1324-1326
Activation of the complement cascade is an important mechanism for antiphospholipid antibody-mediated thrombosis. We examined the effects of rEV576 (coversin), a recombinant protein inhibitor of complement factor 5 activation, on antiphospholipid ant