Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Zuriñe, Baz"'
Autor:
Luka Rejc, Vanessa Gómez-Vallejo, Ana Joya, Gemma Arsequell, Ander Egimendia, Pilar Castellnou, Xabier Ríos-Anglada, Unai Cossío, Zuriñe Baz, Leyre Iglesias, Estibaliz Capetillo-Zarate, Pedro Ramos-Cabrer, Abraham Martin, Jordi Llop
Publikováno v:
Alzheimer’s Research & Therapy, Vol 14, Iss 1, Pp 1-14 (2022)
Abstract Background Validation of new biomarkers of Alzheimer disease (AD) is crucial for the successful development and implementation of treatment strategies. Additional to traditional AT(N) biomarkers, neuroinflammation biomarkers, such as translo
Externí odkaz:
https://doaj.org/article/891cd9332c3e445593fa1436c0d14dde
Autor:
James Morgan, Oscar Moreno, Mariana Alves, Zuriñe Baz, Aida Menéndez Méndez, Hanna Leister, Ciara Melia, Jonathon Smith, Alexander Visekruna, Annette Nicke, Anindya Bhattacharya, Marc Ceusters, David C. Henshall, Vanessa Gómez‐Vallejo, Jordi Llop, Tobias Engel
Publikováno v:
Epilepsia. 64:511-523
Autor:
James, Morgan, Oscar, Moreno, Mariana, Alves, Zuriñe, Baz, Aida, Menéndez Méndez, Hanna, Leister, Ciara, Melia, Jonathon, Smith, Alexander, Visekruna, Annette, Nicke, Anindya, Bhattacharya, Marc, Ceusters, David C, Henshall, Vanessa, Gómez-Vallejo, Jordi, Llop, Tobias, Engel
Publikováno v:
Epilepsia.
The P2X7 receptor (P2X7R) is an important contributor to neuroinflammation, responding to extracellularly released ATP. Expression of the P2X7R is increased in the brain in experimental and human epilepsy and genetic or pharmacologic targeting of the
Publikováno v:
Molecules, Vol 20, Iss 5, Pp 7495-7508 (2015)
Dicarba-closo-dodecaboranes, commonly known as carboranes, possess unique physico-chemical properties and can be used as hydrophobic moieties during the design of new drugs or radiotracers. In this work, we report the synthesis of two analogues of 2-
Externí odkaz:
https://doaj.org/article/a219019e3bf744d383147a93b586f239
Autor:
Krishna R. Pulagam, Kiran B. Gona, Vanessa Gómez-Vallejo, Jan Meijer, Carolin Zilberfain, Irina Estrela-Lopis, Zuriñe Baz, Unai Cossío, Jordi Llop
Publikováno v:
Molecules, Vol 24, Iss 19, p 3609 (2019)
Background: Boron Neutron Capture Therapy (BNCT) is a binary approach to cancer therapy that requires accumulation of boron atoms preferentially in tumour cells. This can be achieved by using nanoparticles as boron carriers and taking advantage of th
Externí odkaz:
https://doaj.org/article/c32cceb230c94316b4e4cdef69b72b12
Autor:
Silvia Alonso-de Castro, Emmanuel Ruggiero, Aitor Lekuona Fernández, Unai Cossío, Zuriñe Baz, Dorleta Otaegui, Vanessa Gómez-Vallejo, Daniel Padro, Jordi Llop, Luca Salassa
Publikováno v:
Inorganics, Vol 7, Iss 5, p 60 (2019)
Lanthanide-doped upconverting nanoparticles (UCNPs) transform near infrared light (NIR) into higher-energy UV and visible light by multiphotonic processes. Owing to such unique feature, UCNPs have found application in optical imaging and have been in
Externí odkaz:
https://doaj.org/article/47b6dea9fd0746f08f65724d3907bb71
Autor:
Jesús Jiménez-Barbero, Edurne Mujica, Luka Rejc, Vanessa Gómez-Vallejo, Ellen Y. Cotrina, Zuriñe Baz, Jordi Quintana, Isabel Cardoso, Xabier Rios, Tiago Gião, Unai Cossío, Gemma Arsequell, Jordi Llop
Publikováno v:
Journal of Alzheimer's Disease. 77:99-112
Background: Transthyretin (TTR) is a tetrameric, amyloid-β (Aβ)-binding protein, which reduces Aβ toxicity. The TTR/Aβ interaction can be enhanced by a series of small molecules that stabilize its tetrameric form. Hence, TTR stabilizers might act
Autor:
Luka Rejc, Jatish Kumar, Vanessa Gómez-Vallejo, Carlos Renero-Lecuna, Zuriñe Baz, Angelica Facoetti, Saverio Altieri, Desire Di Silvio, Krishna R. Pulagam, Ana Sánchez-Iglesias, Luis M. Liz-Marzán, Kepa B. Uribe, Jordi Llop, Angel M. Martínez-Villacorta, Ane Ruiz de Angulo, Unai Cossío, Malou Henriksen-Lacey, Alexandra Charalampopoulou, Vished Kumar, Nicoletta Protti
The incidence and mortality of cancer demand more innovative approaches and combination therapies to increase treatment efficacy and decrease off-target side effects. We describe a boron-rich nanoparticle composite with potential applications in both
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cbcf78076430dc142e9598e09ec569c
https://zenodo.org/record/6108885
https://zenodo.org/record/6108885
Autor:
Oscar Moreno, Abraham Martín, Pilar Castellnou, Unai Cossío, Albert Giralt, Jordi Llop, Pedro Ramos-Cabrer, Ander Egimendia, Rossana Passannante, Ana Joya, Xabier Ríos-Anglada, Estibaliz Capetillo-Zarate, Stanislav Gobec, Magdalena Sastre, Urban Košak, Damijan Knez, Vanessa Gómez-Vallejo, Luka Rejc, Zuriñe Baz, Mariel Marder, Ignacio Tobalina-Larrea
Publikováno v:
Theranostics
Addi. Archivo Digital para la Docencia y la Investigación
instname
Addi: Archivo Digital para la Docencia y la Investigación
Universidad del País Vasco
Dipòsit Digital de la UB
Universidad de Barcelona
Addi. Archivo Digital para la Docencia y la Investigación
instname
Addi: Archivo Digital para la Docencia y la Investigación
Universidad del País Vasco
Dipòsit Digital de la UB
Universidad de Barcelona
Purpose: The increase in butyrylcholinesterase (BChE) activity in the brain of Alzheimer disease (AD) patients and animal models of AD position this enzyme as a potential biomarker of the disease. However, the information on the ability of BChE to se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78aa3f6c23115abd785a53a122b059cb
http://hdl.handle.net/10810/51929
http://hdl.handle.net/10810/51929
Autor:
Zuriñe Baz, Jordi Llop, Kepa B. Uribe, Unai Cossío, Danielle J. Vugts, Rossana Passannante, Kepa Zamacola, Krishna R. Pulagam, Natalia Herrero-Álvarez, María M. Caffarel, Irene V. J. Feiner, Charles H. Lawrie, Vanessa Gómez-Vallejo, Luka Rejc, Cristina Simó
Publikováno v:
Journal of Materials Chemistry B, 9(2), 410-420. Royal Society of Chemistry
Feiner, I V J, Pulagam, K R, Uribe, K B, Passannante, R, Simó, C, Zamacola, K, Gómez-Vallejo, V, Herrero-Álvarez, N, Cossío, U, Baz, Z, Caffarel, M M, Lawrie, C H, Vugts, D J, Rejc, L & Llop, J 2021, ' Pre-targeting with ultra-small nanoparticles : Boron carbon dots as drug candidates for boron neutron capture therapy ', Journal of Materials Chemistry B, vol. 9, no. 2, pp. 410-420 . https://doi.org/10.1039/d0tb01880e
Feiner, I V J, Pulagam, K R, Uribe, K B, Passannante, R, Simó, C, Zamacola, K, Gómez-Vallejo, V, Herrero-Álvarez, N, Cossío, U, Baz, Z, Caffarel, M M, Lawrie, C H, Vugts, D J, Rejc, L & Llop, J 2021, ' Pre-targeting with ultra-small nanoparticles : Boron carbon dots as drug candidates for boron neutron capture therapy ', Journal of Materials Chemistry B, vol. 9, no. 2, pp. 410-420 . https://doi.org/10.1039/d0tb01880e
Boron neutron capture therapy (BNCT) is a promising cancer treatment exploiting the neutron capture capacity and subsequent fission reaction of boron-10. The emergence of nanotechnology has encouraged the development of nanocarriers capable of accumu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43b24763b27d56283a890afefc30e64a
https://research.vumc.nl/en/publications/b4152368-c733-403a-92c9-3a8f7e4de220
https://research.vumc.nl/en/publications/b4152368-c733-403a-92c9-3a8f7e4de220