Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Zuqin Nie"'
Autor:
Zuqin Nie, Chunhua Guo, Subhendu K Das, Carson C Chow, Eric Batchelor, S Stoney Simons Jnr, David Levens
Publikováno v:
eLife, Vol 9 (2020)
Supraphysiological MYC levels are oncogenic. Originally considered a typical transcription factor recruited to E-boxes (CACGTG), another theory posits MYC a global amplifier increasing output at all active promoters. Both models rest on large-scale g
Externí odkaz:
https://doaj.org/article/0acc578d75da4e5c892d7a40c0cd7806
Autor:
Olga Zaytseva, Naomi C. Mitchell, Damien Muckle, Caroline Delandre, Zuqin Nie, Janis K. Werner, John T. Lis, Eduardo Eyras, Ross D. Hannan, David L. Levens, Owen J. Marshall, Leonie M. Quinn
Publikováno v:
Development. 150
The first characterised FUSE Binding Protein family member, FUBP1, binds single-stranded DNA to activate MYC transcription. Psi, the sole FUBP protein in Drosophila, binds RNA to regulate P-element and mRNA splicing. Our previous work revealed pro-gr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98ab2da52a265c5dbf279ae37c97a857
https://doi.org/10.1242/dev.201563
https://doi.org/10.1242/dev.201563
Autor:
Jie Mu, David Levens, Zuqin Nie, Ballachanda N. Devaiah, Dinah S. Singer, Dan Cheng, Sheetal Uppal, Jocelyn D. Weissman, Laura Baranello, Ben Akman
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Dysregulation of MYC protein levels is associated with most human cancers. MYC is regulated by both transcription and protein stability. BRD4, a driver of oncogenesis that activates Myc transcription, is being investigated as a therapeut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab7f4bef22c081eb0a68dcdb1b8bb462
https://doi.org/10.1073/pnas.1919507117
https://doi.org/10.1073/pnas.1919507117
Autor:
Subhendu K. Das, Vladislav Kuzin, Donald P. Cameron, Suzanne Sanford, Rajiv Kumar Jha, Zuqin Nie, Marta Trullols Rosello, Ronald Holewinski, Thorkell Andresson, Jan Wisniewski, Toyoaki Natsume, David H. Price, Brian A. Lewis, Fedor Kouzine, David Levens, Laura Baranello
Publikováno v:
Molecular cell. 82(1)
High-intensity transcription and replication supercoil DNA to levels that can impede or halt these processes. As a potent transcription amplifier and replication accelerator, the proto-oncogene MYC must manage this interfering torsional stress. By co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12939a7d578d25c9b8c7f195979cc24b
https://pubmed.ncbi.nlm.nih.gov/34912109
https://pubmed.ncbi.nlm.nih.gov/34912109
Autor:
Chunhua Guo, David Levens, Carson C. Chow, Zuqin Nie, S Stoney Simons Jnr, Eric Batchelor, Subhendu K. Das
Publikováno v:
eLife
eLife, Vol 9 (2020)
eLife, Vol 9 (2020)
Supraphysiological MYC levels are oncogenic. Originally considered a typical transcription factor recruited to E-boxes (CACGTG), another theory posits MYC a global amplifier increasing output at all active promoters. Both models rest on large-scale g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::830e2325382b7077a18c3f12d95be3b7
http://europepmc.org/articles/PMC7384857
http://europepmc.org/articles/PMC7384857
Autor:
Owen J. Marshall, John T. Lis, Janis Werner, Naomi C. Mitchell, Caroline Delandre, Zuqin Nie, Leonie M. Quinn, Maurits Evers, Ross D. Hannan, David Levens, Olga Zaytseva
Psi, the sole FUSE Binding Protein (FUBP) family single stranded DNA/RNA binding protein inDrosophila, is essential for proper cell and tissue growth, however its mechanism of function remains unclear. Here we use Targeted DamID combined with RNA-seq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75d647429badaef77896c3277a8ea1c8
https://doi.org/10.1101/2020.05.13.094664
https://doi.org/10.1101/2020.05.13.094664
Autor:
Ross D. Hannan, Rodney B. Luwor, Naomi C Mitchell, Linda M. Parsons, Olga Zaysteva, David Levens, Leonie M. Quinn, Jue Er Amanda Lee, Thomas Mb Ware, Gretchen Poortinga, Zuqin Nie, Linna Guo
Publikováno v:
Nucleic Acids Research
Despite two decades of research, the major function of FBP-family KH domain proteins during animal development remains controversial. The literature is divided between RNA processing and transcriptional functions for these single stranded nucleic aci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ead694291a542cbe00cf3eec2f958002
http://europepmc.org/articles/PMC5027480
http://europepmc.org/articles/PMC5027480
Autor:
Devaiah, Ballachanda N., Jie Mu, Akman, Ben, Uppal, Sheetal, Weissman, Jocelyn D., Dan Cheng, Baranello, Laura, Zuqin Nie, Levens, David, Singer, Dinah S.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 6/16/2020, Vol. 117 Issue 24, p13457-13467, 11p
Autor:
Gang Wei, Zuqin Nie, Gangqing Hu, Kairong Cui, Douglas R. Green, Ruoning Wang, Keji Zhao, Wolfgang Resch, Rafael Casellas, Arito Yamane, Lino Tessarollo, David Levens
Publikováno v:
Cell. 151(1):68-79
SummaryThe c-Myc HLH-bZIP protein has been implicated in physiological or pathological growth, proliferation, apoptosis, metabolism, and differentiation at the cellular, tissue, or organismal levels via regulation of numerous target genes. No princip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4a3a438dd6882cda15e6b8981cd8c17