Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Zuomei Li"'
Autor:
W. Cameron Black, Michael Zinda, Jordan T.F. Young, Zuomei Li, Yael Mamane, Rino Stocco, Martine Hamel, Artur Veloso, Victoria Rimkunas, Amina Mulani, Kathryn Skorey, Sabrina Vignini-Hammond, Chloe Fugère-Desjardins, William Yang, Hunain Alam, Amandine Chefson, Shou Yun Yin, Marie-Eve Leclaire, Li Li, Sara Fournier, Lee D. Fader, Stéphane Dorich, Valerie Dumais, Émilie Dumas-Bérube, Charles Pellerin, Alexander Skeldon, Robert Papp, Michal Zimmermann, Anne Roulston
Supplementary Methods, Tables, Figures and References
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::062cfaf9177f49a3206feb599326f494
https://doi.org/10.1158/1535-7163.22896018
https://doi.org/10.1158/1535-7163.22896018
Autor:
W. Cameron Black, Michael Zinda, Jordan T.F. Young, Zuomei Li, Yael Mamane, Rino Stocco, Martine Hamel, Artur Veloso, Victoria Rimkunas, Amina Mulani, Kathryn Skorey, Sabrina Vignini-Hammond, Chloe Fugère-Desjardins, William Yang, Hunain Alam, Amandine Chefson, Shou Yun Yin, Marie-Eve Leclaire, Li Li, Sara Fournier, Lee D. Fader, Stéphane Dorich, Valerie Dumais, Émilie Dumas-Bérube, Charles Pellerin, Alexander Skeldon, Robert Papp, Michal Zimmermann, Anne Roulston
Ataxia telangiectasia and Rad3-related (ATR) kinase protects genome integrity during DNA replication. RP-3500 is a novel, orally bioavailable clinical-stage ATR kinase inhibitor (NCT04497116). RP-3500 is highly potent with IC50 values of 1.0 and 0.33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a51beae2425d617ba7d0ef61e96c7e6
https://doi.org/10.1158/1535-7163.c.6651330.v1
https://doi.org/10.1158/1535-7163.c.6651330.v1
Autor:
Zuomei Li, Jeffrey M. Besterman, A. Robert MacLeod, Daniel Delorme, Oscar Moradei, Sylvain Lefebvre, Jubrail Rahil, Hélène Ste-Croix, James J. Wang, Jeffrey Gillespie, Marie-France Robert, Nancy Z. Zhou, Ai-Hua Lu, Jianhong Liu, Ann Kalita, Marie-Claude Trachy-Bourget, Pu Theresa Yan, Yu Hou, Claire Bonfils, Marielle Fournel
Nonselective inhibitors of human histone deacetylases (HDAC) are known to have antitumor activity in mice in vivo, and several of them are under clinical investigation. The first of these, Vorinostat (SAHA), has been approved for treatment of cutaneo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37be0158a4c3ff3f1783a4ed1271cd1d
https://doi.org/10.1158/1535-7163.c.6531123.v1
https://doi.org/10.1158/1535-7163.c.6531123.v1
Autor:
Zuomei Li, Jeffrey M. Besterman, A. Robert MacLeod, Daniel Delorme, Oscar Moradei, Sylvain Lefebvre, Jubrail Rahil, Hélène Ste-Croix, James J. Wang, Jeffrey Gillespie, Marie-France Robert, Nancy Z. Zhou, Ai-Hua Lu, Jianhong Liu, Ann Kalita, Marie-Claude Trachy-Bourget, Pu Theresa Yan, Yu Hou, Claire Bonfils, Marielle Fournel
Supplementary Table 1 from MGCD0103, a novel isotype-selective histone deacetylase inhibitor, has broad spectrum antitumor activity in vitro and in vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::489f53ab3050b1c461753e8c3470afee
https://doi.org/10.1158/1535-7163.22483368
https://doi.org/10.1158/1535-7163.22483368
Autor:
Zuomei Li, Jeffrey M. Besterman, A. Robert MacLeod, Daniel Delorme, Oscar Moradei, Sylvain Lefebvre, Jubrail Rahil, Hélène Ste-Croix, James J. Wang, Jeffrey Gillespie, Marie-France Robert, Nancy Z. Zhou, Ai-Hua Lu, Jianhong Liu, Ann Kalita, Marie-Claude Trachy-Bourget, Pu Theresa Yan, Yu Hou, Claire Bonfils, Marielle Fournel
Supplementary Table 2 from MGCD0103, a novel isotype-selective histone deacetylase inhibitor, has broad spectrum antitumor activity in vitro and in vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dfa14777fa57c3391ea3a30617e6ac2
https://doi.org/10.1158/1535-7163.22483365.v1
https://doi.org/10.1158/1535-7163.22483365.v1
Autor:
Jessica L. Dennison, Claude-Henry Volmar, Farzaneh Modarresi, Danbing Ke, James Wang, Emilie Gravel, Sabrina Hammond-Vignini, Zuomei Li, James A. Timmons, Ines Lohse, Marshall A. Hayward, Shaun P. Brothers, Claes Wahlestedt
Publikováno v:
Journal of Alzheimer's Disease. 86:173-190
Background: Alzheimer’s disease (AD) has minimally effective treatments currently. High concentrations of resveratrol, a polyphenol antioxidant found in plants, have been reported to affect several AD-related and neuroprotective genes. To address t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4bd0b4f38e5615bcf23085216c597189
https://doi.org/10.3233/jad-215370
https://doi.org/10.3233/jad-215370
Autor:
Anne Roulston, Michal Zimmermann, Robert Papp, Alexander Skeldon, Charles Pellerin, Émilie Dumas-Bérube, Valerie Dumais, Stéphane Dorich, Lee D. Fader, Sara Fournier, Li Li, Marie-Eve Leclaire, Shou Yun Yin, Amandine Chefson, Hunain Alam, William Yang, Chloe Fugère-Desjardins, Sabrina Vignini-Hammond, Kathryn Skorey, Amina Mulani, Victoria Rimkunas, Artur Veloso, Martine Hamel, Rino Stocco, Yael Mamane, Zuomei Li, Jordan T.F. Young, Michael Zinda, W. Cameron Black
Publikováno v:
Molecular Cancer Therapeutics. 21:245-256
Ataxia telangiectasia and Rad3-related (ATR) kinase protects genome integrity during DNA replication. RP-3500 is a novel, orally bioavailable clinical-stage ATR kinase inhibitor (NCT04497116). RP-3500 is highly potent with IC50 values of 1.0 and 0.33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c5c2c693c809fd51b04d00ce59692a4
https://doi.org/10.1158/1535-7163.mct-21-0615
https://doi.org/10.1158/1535-7163.mct-21-0615
Autor:
Jessica L. Dennison, Claude-Henry Volmar, Farzaneh Modarresi, Danbing Ke, James Wang, Emilie Gravel, Sabrina Hammond-Vignini, Zuomei Li, James A. Timmons, Ines Lohse, Marshall A. Hayward, Shaun P. Brothers, Claes Wahlestedt
Publikováno v:
Journal of Alzheimer's Disease. 88:385-385
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef149f5219342d1ecf769fc7d5172456
https://doi.org/10.3233/jad-229006
https://doi.org/10.3233/jad-229006
Autor:
Anne Roulston, Michal Zimmerman, Robert Papp, Alex Skeldon, Charles Pellerin, Émilie Dumas-Bérube, Valerie Dumais, Stephane Dorich, Sara Fournier, Li Li, Marie-Ève Leclaire, Shou Yun Yin, Amandine Chefson, Hunain Alam, William Yang, Chloe Fugère-Desjardins, Sabrina Hammond, Kathryn Skorey, Amina Mulani, Victoria Rimkunas, Artur Veloso, Martine Hamel, Rino Stocco, Yael Mamane, Zuomei Li, Jordan Young, Mike Zinda, Cameron Black
Publikováno v:
Molecular Cancer Therapeutics. 20:P054-P054
Background: Ataxia telangiectasia and Rad3-related (ATR) protein kinase is a key mediator of cellular DNA damage repair (DDR) and is activated in response to DNA replication stress. ATR is attractive as a drug target in tumors with loss-of-function a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64546a898e05e3470c5622263c464f40
https://doi.org/10.1158/1535-7163.targ-21-p054
https://doi.org/10.1158/1535-7163.targ-21-p054
Publikováno v:
Journal of the chemical society of pakistan. 43:587-587
In the present study, the crude polysaccharides from pomegranate peels (CPP) were prepared by compound enzyme-extraction technology, and the response surface methodology was used to optimize the extraction parameters. Box–Behnken design (BBD) was a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f3b0dc26d54b87a5faf714a1b7dfc85
https://doi.org/10.52568/000601/jcsp/43.05.2021
https://doi.org/10.52568/000601/jcsp/43.05.2021