Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Zuolin Cheng"'
Autor:
Raquel Santana da Cruz, Elissa J. Carney, Johan Clarke, Hong Cao, M. Idalia Cruz, Carlos Benitez, Lu Jin, Yi Fu, Zuolin Cheng, Yue Wang, Sonia de Assis
Publikováno v:
Breast Cancer Research, Vol 20, Iss 1, Pp 1-14 (2018)
Abstract Background While many studies have shown that maternal factors in pregnancy affect the cancer risk for offspring, few studies have investigated the impact of paternal exposures on their progeny’s risk of this disease. Population studies ge
Externí odkaz:
https://doaj.org/article/5e1395a6464a4afeacce43a1f5f115c0
Publikováno v:
2022 IEEE International Conference on Bioinformatics and Biomedicine (BIBM).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23db47015c49c6eb4fb1086b5bad71f9
https://doi.org/10.1109/bibm55620.2022.9995574
https://doi.org/10.1109/bibm55620.2022.9995574
Autor:
Chiung-Ting Wu, Minjie Shen, Dongping Du, Zuolin Cheng, Sarah J Parker, Yingzhou Lu, Jennifer E Van Eyk, Guoqiang Yu, Robert Clarke, David M Herrington, Yue Wang
Publikováno v:
Bioinformatics advances. 2(1)
Motivation Data normalization is essential to ensure accurate inference and comparability of gene expression measures across samples or conditions. Ideally, gene expression data should be rescaled based on consistently expressed reference genes. Howe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cdda51e539b1643a38ca9f20ee61707
https://pubmed.ncbi.nlm.nih.gov/36330358
https://pubmed.ncbi.nlm.nih.gov/36330358
Autor:
Yingzhou Lu, Chiung-Ting Wu, Sarah J Parker, Zuolin Cheng, Georgia Saylor, Jennifer E Van Eyk, Guoqiang Yu, Robert Clarke, David M Herrington, Yue Wang
Publikováno v:
Bioinformatics Advances. 2
Motivation Ideally, a molecularly distinct subtype would be composed of molecular features that are expressed uniquely in the subtype of interest but in no others—so-called marker genes (MGs). MG plays a critical role in the characterization, class
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f9d16ae26a1285c065637fba0e97b12
https://doi.org/10.1093/bioadv/vbac037
https://doi.org/10.1093/bioadv/vbac037
Autor:
Yungui Zhou, Shiaoching Gong, John Hardy, Qingyun Li, Linas Mazutis, Li Fan, Yue Qiu, Pearly Ye, Dennis W. Dickson, Tara E. Tracy, Xiang Niu, Lay Kodama, Michael DeTure, Bin Zhang, Subhash C. Sinha, Wenjie Luo, Xueting Wang, Xueqiao Jiang, Lei Xie, Guoqiang Yu, Fei Wang, Li Gan, Zuolin Cheng, Georgia R. Frost, Maria Telpoukhovskaia, Rose Horowitz, John Q. Trajnowski, Man Ying Wong, Fuying Gao, Giovanni Coppola, Yaqiao Li, Virginia M.-Y. Lee, Faten A. Sayed, Lu Zhou, Hansruedi Mathys, Joe C. Udeochu, David Le, Gillian K. Carling, Matthew Brendel, Minghui Wang
Publikováno v:
Sci Transl Med
The hemizygous R47H variant of Triggering receptor expressed on myeloid cells 2 (TREM2), a microglia-specific gene in the brain, increases risk for late-onset Alzheimer’s disease (AD). Using transcriptomic analysis of single-nuclei from brain tissu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7bfaa5135ff0c66a29779f068ec0946
https://doi.org/10.1126/scitranslmed.abe3947
https://doi.org/10.1126/scitranslmed.abe3947
Autor:
Hansruedi Mathys, Yue Qiu, Joe C. Udeochu, David Le, Lei Xie, Linas Mazutis, Xueting Wang, Michael DeTure, Georgia R. Frost, Gillian K. Carling, John Hardy, Li Fan, Wenjie Luo, Li Gan, Zuolin Cheng, Lay Kodama, Fei Wang, Giovanni Coppola, Maria Telpoukhovskaia, Man Ying Wong, Fuying Gao, Minghui Wang, Matthew Brendel, Guoqiang Yu, Tara E. Tracy, Xiang Niu, Bin Zhang, Yaqiao Li, Faten A. Sayed, Dennis W. Dickson, Yungui Zhou, Lu Zhou, Xueqiao Jiang, Shiaoching Gong, Qingyun Li
The hemizygous R47H variant ofTREM2, a microglia-specific gene in the brain, increases risk for late-onset Alzheimer’s disease (AD). In this study, we identified a subpopulation of microglia with disease-enhancing proinflammatory signatures associa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c0aaf393e58f3fa98f504068eff9eae7
https://doi.org/10.1101/2020.07.24.218719
https://doi.org/10.1101/2020.07.24.218719
Autor:
Lingli Xu, Zuolin Cheng, Chuntao Zhao, Qiaojun He, Feng Zhang, Jeremy N. Rich, Liguo Zhang, Q. Richard Lu, Jiajia Wang, Andrew S. Potter, Danyang He, Xinran Dong, Xuelian He, Ravinder Verma, Bruce J. Aronow, S. Steven Potter, Ronald R. Waclaw, Wenhao Zhou, Qinjie Weng, Perry J. Blackshear, Yunfei Liao, Jincheng Wang, Qian Zhou, Mei Xin, Guoqiang Yu, Mario L. Suvà
Publikováno v:
Cell Stem Cell
The identity and degree of heterogeneity of glial progenitors and their contributions to brain tumor malignancy remain elusive. By applying lineage-targeted single-cell transcriptomics, we uncover an unanticipated diversity of glial progenitor pools
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::648ae6293bfee148881fb85556f0c203
https://europepmc.org/articles/PMC6669001/
https://europepmc.org/articles/PMC6669001/
Autor:
Joe C. Udeochu, Yungui Zhou, Qingyun Li, David Le, Kenneth S. Kosik, Li Gan, Lu Zhou, Guoqiang Yu, Lihong Zhan, Yaqiao Li, Faten A. Sayed, Claire D. Clelland, Jon Iker Etchegaray, Elmer Guzman, Zuolin Cheng, Lay Kodama
Publikováno v:
Nature neuroscience
Sex is a key modifier of neurological disease outcomes. Microglia are implicated in neurological diseases and modulated by microRNAs, but it is unknown whether microglial microRNAs have sex-specific influences on disease. We show in mice that microgl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baade15bf2e93db65900ae8815be634e
https://pubmed.ncbi.nlm.nih.gov/31873194
https://pubmed.ncbi.nlm.nih.gov/31873194
Autor:
Qingyun Li, Mariko L. Bennett, Lu Zhou, Lu O. Sun, Gunsagar S. Gulati, Stephen R. Quake, Spyros Darmanis, Guoqiang Yu, Ben A. Barres, Norma F. Neff, Tony Wyss-Coray, Julia Marschallinger, Laura E. Clarke, Jennifer Okamoto, Zuolin Cheng
SummaryMicroglia are increasingly recognized for their major contributions during brain development and neurodegenerative disease. It is currently unknown if these functions are carried out by subsets of microglia during different stages of developme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4407972adcd6de6e0d21134c8617f86
https://doi.org/10.1101/406363
https://doi.org/10.1101/406363
Autor:
Sonia de Assis, Johan Clarke, M. Idalia Cruz, Lu Jin, Zuolin Cheng, Raquel Santana da Cruz, Yi Fu, Carlos Benitez, Elissa Carney, Yue Wang, Hong Cao
Publikováno v:
Breast Cancer Research : BCR
Breast Cancer Research, Vol 20, Iss 1, Pp 1-14 (2018)
Breast Cancer Research, Vol 20, Iss 1, Pp 1-14 (2018)
Background While many studies have shown that maternal factors in pregnancy affect the cancer risk for offspring, few studies have investigated the impact of paternal exposures on their progeny’s risk of this disease. Population studies generally s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::597031d07d202af294e0bd724e5668af
https://hdl.handle.net/10919/84950
https://hdl.handle.net/10919/84950