Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Zuojing Yin"'
Autor:
Bingyu Li, Ping Jing, Genhui Zheng, Chenyu Pi, Lu Zhang, Zuojing Yin, Lijun Xu, Jingxuan Qiu, Hua Gu, Tianyi Qiu, Jianmin Fang
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-12 (2023)
Abstract Neoantigen vaccines are one of the most effective immunotherapies for personalized tumour treatment. The current immunogen design of neoantigen vaccines is usually based on whole-genome sequencing (WGS) and bioinformatics prediction that foc
Externí odkaz:
https://doaj.org/article/07e15a9157ce4645933c729409384272
Autor:
Jian Gao, Zuojing Yin, Zhuanbin Wu, Zhen Sheng, Chao Ma, Rui Chen, Xiongwen Zhang, Kailin Tang, Jian Fei, Zhiwei Cao
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
BackgroundDesigning combination drugs for malignant cancers has been restricted due to the scarcity of synergy-medicated targets, while some natural compounds have demonstrated potential to enhance anticancer effects.MethodsWe here explored the feasi
Externí odkaz:
https://doaj.org/article/e9229390ddbc47b3a0e96d61d96883c8
Autor:
Qingchen Zhang, Lu Zhang, Chen Zhou, Yiyan Yang, Zuojing Yin, Dingfeng Wu, Kailin Tang, Zhiwei Cao
Publikováno v:
BMC Bioinformatics, Vol 20, Iss 1, Pp 1-9 (2019)
Abstract Background Functional antibody genes are often assembled by VDJ recombination and then diversified by somatic hypermutation. Identifying the combination of sourcing germline genes is critical to understand the process of antibody maturation,
Externí odkaz:
https://doaj.org/article/66dd0a90da914f1aa54db3fcf002a886
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
BackgroundColon cancer is one of the most common health threats for humans since its high morbidity and mortality. Detecting potential prognosis risk biomarkers (PRBs) is essential for the improvement of therapeutic strategies and drug development. C
Externí odkaz:
https://doaj.org/article/015d338be63944b1862d768d244ff753
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
BackgroundThe dysregulation of non-coding RNAs (ncRNAs) such as miRNAs and lncRNAs are associated with the pathogenesis and progression in multiple cancers including solid tumors. Comprehensive investigations of prognosis-related ncRNA markers could
Externí odkaz:
https://doaj.org/article/4f2cf9dd84654e84ab1690ef649f11fb
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Recent development has enabled synergistic drugs in treating a wide range of cancers. Being highly context-dependent, however, identification of successful ones often requires screening of combinational dose on different testing platforms in order to
Externí odkaz:
https://doaj.org/article/fa8b5b8288ab40edb86bbfa27f9a8998
Publikováno v:
Molecules, Vol 22, Iss 12, p 2209 (2017)
The growth and survival of cancer cells are greatly related to their surrounding microenvironment. To understand the regulation under the impact of anti-cancer drugs and their synergistic effects, we have developed a multiscale agent-based model that
Externí odkaz:
https://doaj.org/article/8f4da61057724b63875c4a1f6a38392b
Autor:
Zikun Chen, Tianyi Qiu, Zuojing Yin, Zhiwei Cao, Zeliang Deng, Yiyan Yang, Xinmiao Yan, Kailin Tang
Publikováno v:
Aging (Albany NY)
Though promising, identifying synergistic combinations from a large pool of candidate drugs remains challenging for cancer treatment. Due to unclear mechanism and limited confirmed cases, only a few computational algorithms are able to predict drug s
Autor:
Kailin Tang, Rui Chen, Xiongwen Zhang, Chao Ma, Zuojing Yin, Jian Fei, Jian Gao, Zhuanbin Wu, Zhiwei Cao, Zhen Sheng
Publikováno v:
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
BackgroundDesigning combination drugs for malignant cancers has been restricted due to the scarcity of synergy-medicated targets, while some natural compounds have demonstrated potential to enhance anticancer effects.MethodsWe here explored the feasi
Publikováno v:
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Background The dysregulation of non-coding RNAs (ncRNAs) such as miRNAs and lncRNAs are associated with the pathogenesis and progression in multiple cancers including solid tumors. Comprehensive investigations of prognosis-related ncRNA markers could