Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Zuojian Tang"'
Autor:
Jared P. Steranka, Zuojian Tang, Mark Grivainis, Cheng Ran Lisa Huang, Lindsay M. Payer, Fernanda O. R. Rego, Thiago Luiz Araujo Miller, Pedro A. F. Galante, Sitharam Ramaswami, Adriana Heguy, David Fenyö, Jef D. Boeke, Kathleen H. Burns
Publikováno v:
Mobile DNA, Vol 10, Iss 1, Pp 1-14 (2019)
Abstract Background Transposable elements make up a significant portion of the human genome. Accurately locating these mobile DNAs is vital to understand their role as a source of structural variation and somatic mutation. To this end, laboratories h
Externí odkaz:
https://doaj.org/article/efba34029f4943b4afc26303ad2a137b
Autor:
Eric D Schafler, Phillip A Thomas, Susan Ha, Yu Wang, Keria Bermudez-Hernandez, Zuojian Tang, David Fenyö, Margarita Vigodner, Susan K Logan
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0195747 (2018)
Male mammals must simultaneously produce prodigious numbers of sperm and maintain an adequate reserve of stem cells to ensure continuous production of gametes throughout life. Failures in the mechanisms responsible for balancing germ cell differentia
Externí odkaz:
https://doaj.org/article/c9dc4c718d7947c08dac752f8d5bf4ab
Autor:
Martina Mijušković, Stuart M Brown, Zuojian Tang, Cory R Lindsay, Efstratios Efstathiadis, Ludovic Deriano, David B Roth
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e48314 (2012)
Defining the architecture of a specific cancer genome, including its structural variants, is essential for understanding tumor biology, mechanisms of oncogenesis, and for designing effective personalized therapies. Short read paired-end sequencing is
Externí odkaz:
https://doaj.org/article/962888915b594026a5315fb26a5bb960
Autor:
Kam-Meng Tchou-Wong, Kathrin Kiok, Zuojian Tang, Thomas Kluz, Adriana Arita, Phillip R Smith, Stuart Brown, Max Costa
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17728 (2011)
Occupational exposure to nickel compounds has been associated with lung and nasal cancers. We have previously shown that exposure of the human lung adenocarcinoma A549 cells to NiCl(2) for 24 hr significantly increased global levels of trimethylated
Externí odkaz:
https://doaj.org/article/09e373286f1e4d7b8e79546985e6a345
Autor:
Kathleen G. Dickman, Ivana Vuković Brinar, Damir Dittrich, Elisa Venturini, Fran Borovečki, Sandra Karanović, Daniel S. Lee, Stephanie Villar, Želimir Stipančić, Magali Olivier, Karla Tomić, Bojan Jelaković, Jiri Zavadil, Claire Renard, Arthur P. Grollman, Krešimir Karlović, Adam Lorch, Zuojian Tang, Neda Slade, Maude Ardin
Publikováno v:
International Journal of Cancer
Recurrent upper tract urothelial carcinomas (UTUCs) arise in the context of nephropathy linked to exposure to the herbal carcinogen aristolochic acid (AA). Here we delineated the molecular programs underlying UTUC tumorigenesis in patients from endem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f25275ec5f5b573d868cf440c158411
Autor:
Cheuk Hei Ho, Jessica E. Treisman, Chiara Paolantoni, Stuart M. Brown, Praveen Bawankar, Zuojian Tang, Jean-Yves Roignant
Publikováno v:
EMBO Rep
The exon junction complex controls the translation, degradation, and localization of spliced mRNAs, and three of its core subunits also play a role in splicing. Here, we show that a fourth subunit, Barentsz, has distinct functions within and separate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bf4635437ae1886d5b477f775bf14d1
https://europepmc.org/articles/PMC8728599/
https://europepmc.org/articles/PMC8728599/
Autor:
Jef D. Boeke, Paolo Mita, Neta Agmon, Itai Yanai, Maayan Baron, Tobias Schraink, Zuojian Tang, James A. Martin, Jun Chen, Jasmine Temple, David Fenyö, Benjamin P. Tu
Publikováno v:
Nucleic Acids Research
Cross-species pathway transplantation enables insight into a biological process not possible through traditional approaches. We replaced the enzymes catalyzing the entire Saccharomyces cerevisiae adenine de novo biosynthesis pathway with the human pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e7f35911059c25100de9f065930e22a
http://europepmc.org/articles/PMC7145547
http://europepmc.org/articles/PMC7145547
Human transposon insertion profiling by sequencing (TIPseq) to map LINE-1 insertions in single cells
Autor:
Lindsay M. Payer, Kathleen H. Burns, Jared P. Steranka, Chunhong Liu, Zuojian Tang, David Fenyö, David L. Keefe, Wilson McKerrow, Jef D. Boeke
Publikováno v:
Philosophical Transactions of the Royal Society B: Biological Sciences
Long interspersed element-1 (LINE-1, L1) sequences, which comprise about 17% of human genome, are the product of one of the most active types of mobile DNAs in modern humans. LINE-1 insertion alleles can cause inherited and de novo genetic diseases,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c873c32905d9b7605dc677e7653b461
http://europepmc.org/articles/PMC7061987
http://europepmc.org/articles/PMC7061987
Publikováno v:
Bioinformatics
Motivation Retrotransposition is an important force in shaping the human genome and is involved in prenatal development, disease and aging. Current genome browsers are not optimized for visualizing the experimental evidence for retrotransposon insert
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8edaeabb87224432061b533b49488881
https://doi.org/10.1093/bioinformatics/btaa244
https://doi.org/10.1093/bioinformatics/btaa244
Autor:
Steranka, Jared, Zuojian Tang, Grivainis, Mark, Huang, Cheng, Payer, Lindsay, Rego, Fernanda, Thiago Miller, Galante, Pedro, Sitharam Ramaswami, Heguy, Adriana, Fenyö, David, Boeke, Jef, Burns, Kathleen
Figure S2. DNA size distributions during TIPseq. a. An Agilent TapeStation image of two samples of purified vectorette PCR DNA is shown with amplicons averaging 1-3 kb. The protocol does not require running samples on TapeStation after vectorette PCR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::090c8302f122d72fcd4150f163ea5809