Zobrazeno 1 - 10
of 141
pro vyhledávání: '"Zuoheng Wang"'
Autor:
Xiaowei Zhuang, Gang Xu, Amei Amei, Dietmar Cordes, Zuoheng Wang, Edwin C. Oh, For the Alzheimer's Disease Neuroimaging Initiative
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 16, Iss 2, Pp n/a-n/a (2024)
Abstract INTRODUCTION The development and progression of Alzheimer's disease (AD) is a complex process, during which genetic influences on phenotypes may also change. Incorporating longitudinal phenotypes in genome‐wide association studies (GWAS) c
Externí odkaz:
https://doaj.org/article/6e940758da954eba8c9159ceb089af1a
Autor:
Xinyu Zhang, Ying Hu, Ral E Vandenhoudt, Chunhua Yan, Vincent C Marconi, Mardge H Cohen, Zuoheng Wang, Amy C Justice, Bradley E Aouizerat, Ke Xu
Publikováno v:
PLoS Pathogens, Vol 20, Iss 3, p e1012063 (2024)
BackgroundEpigenome-wide association studies (EWAS) have identified CpG sites associated with HIV infection in blood cells in bulk, which offer limited knowledge of cell-type specific methylation patterns associated with HIV infection. In this study,
Externí odkaz:
https://doaj.org/article/aa3df9ddc68a4510a06e89e44d913415
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-14 (2023)
Abstract Background Cocaine use (CU) is associated with psychiatric and medical diseases. Little is known about the mechanisms of CU-related comorbidities. Findings from preclinical and clinical studies have suggested that CU is associated with aberr
Externí odkaz:
https://doaj.org/article/267ee5fed7384dd1a73438d967bdead0
iDESC: identifying differential expression in single-cell RNA sequencing data with multiple subjects
Autor:
Yunqing Liu, Jiayi Zhao, Taylor S. Adams, Ningya Wang, Jonas C. Schupp, Weimiao Wu, John E. McDonough, Geoffrey L. Chupp, Naftali Kaminski, Zuoheng Wang, Xiting Yan
Publikováno v:
BMC Bioinformatics, Vol 24, Iss 1, Pp 1-20 (2023)
Abstract Background Single-cell RNA sequencing (scRNA-seq) technology has enabled assessment of transcriptome-wide changes at single-cell resolution. Due to the heterogeneity in environmental exposure and genetic background across subjects, subject e
Externí odkaz:
https://doaj.org/article/98bb000233a34cca8225fba23b3cf131
Autor:
Zicheng Li, Zuoheng Wang, Zhiyuan Chen, Heidi Voegeli, Judith H. Lichtman, Peter Smith, Ju Liu, Andrew T. DeWan, Josephine Hoh
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-26 (2023)
Abstract Background In light of previous studies that profiled breed-specific traits or used genome-wide association studies to refine loci associated with characteristic morphological features in dogs, the field has gained tremendous genetic insight
Externí odkaz:
https://doaj.org/article/c844a516b34548adac863b6003d8b45f
Autor:
David S. Jin, Uma Neelakantan, Cheryl M. Lacadie, Tianying Chen, Brendan Rooney, Yunqing Liu, Weimiao Wu, Zuoheng Wang, Xenophon Papademetris, Ellen J. Hoffman
Publikováno v:
STAR Protocols, Vol 4, Iss 4, Pp 102647- (2023)
Summary: Here, we present Brain Registration and Evaluation for Zebrafish (BREEZE)-mapping, a user-friendly pipeline for the registration and analysis of whole-brain images in larval zebrafish. We describe steps for pre-processing, registration, quan
Externí odkaz:
https://doaj.org/article/4795ebd7a1034f03af9a750bffcf17c2
Autor:
Yunqing Liu, Jiayi Zhao, Taylor S. Adams, Ningya Wang, Jonas C. Schupp, Weimiao Wu, John E. McDonough, Geoffrey L. Chupp, Naftali Kaminski, Zuoheng Wang, Xiting Yan
Publikováno v:
BMC Bioinformatics, Vol 24, Iss 1, Pp 1-2 (2023)
Externí odkaz:
https://doaj.org/article/3da99a1637a2445db9e02f0e0409547c
Autor:
Hellen Weinschutz Mendes, Uma Neelakantan, Yunqing Liu, Sarah E. Fitzpatrick, Tianying Chen, Weimiao Wu, April Pruitt, David S. Jin, Priyanka Jamadagni, Marina Carlson, Cheryl M. Lacadie, Kristen D. Enriquez, Ningshan Li, Dejian Zhao, Sundas Ijaz, Catalina Sakai, Christina Szi, Brendan Rooney, Marcus Ghosh, Ijeoma Nwabudike, Andrea Gorodezky, Sumedha Chowdhury, Meeraal Zaheer, Sarah McLaughlin, Joseph M. Fernandez, Jia Wu, Jeffrey A. Eilbott, Brent Vander Wyk, Jason Rihel, Xenophon Papademetris, Zuoheng Wang, Ellen J. Hoffman
Publikováno v:
Cell Reports, Vol 42, Iss 3, Pp 112243- (2023)
Summary: Advancing from gene discovery in autism spectrum disorders (ASDs) to the identification of biologically relevant mechanisms remains a central challenge. Here, we perform parallel in vivo functional analysis of 10 ASD genes at the behavioral,
Externí odkaz:
https://doaj.org/article/7996517e63554f8b8dc40a353d5ba4fb
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Colorectal cancer (CRC) is now the third most common malignancy to cause mortality worldwide, and its prognosis is of great importance. Recent CRC prognostic prediction studies mainly focused on biomarkers, radiometric images, and end-to-end deep lea
Externí odkaz:
https://doaj.org/article/898f5ad0867243a2bb721620513636a2
Autor:
Avraham Unterman, Tomokazu S. Sumida, Nima Nouri, Xiting Yan, Amy Y. Zhao, Victor Gasque, Jonas C. Schupp, Hiromitsu Asashima, Yunqing Liu, Carlos Cosme, Wenxuan Deng, Ming Chen, Micha Sam Brickman Raredon, Kenneth B. Hoehn, Guilin Wang, Zuoheng Wang, Giuseppe DeIuliis, Neal G. Ravindra, Ningshan Li, Christopher Castaldi, Patrick Wong, John Fournier, Santos Bermejo, Lokesh Sharma, Arnau Casanovas-Massana, Chantal B. F. Vogels, Anne L. Wyllie, Nathan D. Grubaugh, Anthony Melillo, Hailong Meng, Yan Stein, Maksym Minasyan, Subhasis Mohanty, William E. Ruff, Inessa Cohen, Khadir Raddassi, The Yale IMPACT Research Team, Laura E. Niklason, Albert I. Ko, Ruth R. Montgomery, Shelli F. Farhadian, Akiko Iwasaki, Albert C. Shaw, David van Dijk, Hongyu Zhao, Steven H. Kleinstein, David A. Hafler, Naftali Kaminski, Charles S. Dela Cruz
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-23 (2022)
SARS-CoV-2 infection can lead to progressive pathology in patients with COVID-19, but information for this disease progression is sparse. Here the authors use multi-omics approach to profile the immune responses of patients, assessing immune repertoi
Externí odkaz:
https://doaj.org/article/071dfec07b41418ab54ed9c36dc0d83e