Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Zuo-Fei Yuan"'
Autor:
Bitna Lim, Yurika Matsui, Seunghyun Jung, Mohamed Nadhir Djekidel, Wenjie Qi, Zuo-Fei Yuan, Xusheng Wang, Xiaoyang Yang, Nina Connolly, Abbas Shirinifard Pilehroud, Haitao Pan, Fang Wang, Shondra M Pruett-Miller, Kanisha Kavdia, Vishwajeeth Pagala, Yiping Fan, Junmin Peng, Beisi Xu, Jamy C Peng
Publikováno v:
PLoS Biology, Vol 22, Iss 9, p e3002760 (2024)
53BP1 is a well-established DNA damage repair factor that has recently emerged to critically regulate gene expression for tumor suppression and neural development. However, its precise function and regulatory mechanisms remain unclear. Here, we showe
Externí odkaz:
https://doaj.org/article/3af8bfdefb644757874ab04b0b84994b
Autor:
Li Tan, Zhonghe Ke, Gregory Tombline, Nicholas Macoretta, Kevin Hayes, Xiao Tian, Ruitu Lv, Julia Ablaeva, Michael Gilbert, Natarajan V. Bhanu, Zuo-Fei Yuan, Benjamin A. Garcia, Yujiang G. Shi, Yang Shi, Andrei Seluanov, Vera Gorbunova
Publikováno v:
Stem Cell Reports, Vol 9, Iss 5, Pp 1721-1734 (2017)
Summary: Naked mole rat (NMR) is a valuable model for aging and cancer research due to its exceptional longevity and cancer resistance. We observed that the reprogramming efficiency of NMR fibroblasts in response to OSKM was drastically lower than th
Externí odkaz:
https://doaj.org/article/555f64213cd742b0b9d42f0735085c92
Autor:
Johayra Simithy, Simone Sidoli, Zuo-Fei Yuan, Mariel Coradin, Natarajan V. Bhanu, Dylan M. Marchione, Brianna J. Klein, Gleb A. Bazilevsky, Cheryl E. McCullough, Robert S. Magin, Tatiana G. Kutateladze, Nathaniel W. Snyder, Ronen Marmorstein, Benjamin A. Garcia
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
A number of histone lysine modifications related to acetylation have been identified, but their functional significance is unclear. Here, the authors use in vitro and in vivo assays to characterize eight acyl histone post-translational modifications
Externí odkaz:
https://doaj.org/article/d14a3bef3d85449ebebdccbdcf9b9c22
Autor:
Vivek Behera, Aaron J. Stonestrom, Nicole Hamagami, Chris C. Hsiung, Cheryl A. Keller, Belinda Giardine, Simone Sidoli, Zuo-Fei Yuan, Natarajan V. Bhanu, Michael T. Werner, Hongxin Wang, Benjamin A. Garcia, Ross C. Hardison, Gerd A. Blobel
Publikováno v:
Cell Reports, Vol 27, Iss 2, Pp 400-415.e5 (2019)
Summary: Global changes in chromatin organization and the cessation of transcription during mitosis are thought to challenge the resumption of appropriate transcription patterns after mitosis. The acetyl-lysine binding protein BRD4 has been previousl
Externí odkaz:
https://doaj.org/article/8b145c50765d4778bd5ce4df11b251aa
Autor:
Izabel Moraes, Zuo-Fei Yuan, Shichong Liu, Glaucia Mendes Souza, Benjamin A Garcia, J Armando Casas-Mollano
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0134586 (2015)
Histones are the main structural components of the nucleosome, hence targets of many regulatory proteins that mediate processes involving changes in chromatin. The functional outcome of many pathways is "written" in the histones in the form of post-t
Externí odkaz:
https://doaj.org/article/5fbeee6b9a634bc1845e3b9bff2f06ad
Autor:
Bitna Lim, Mohamed Nadhir Djekidel, Yurika Matsui, Seunghyun Jung, Zuo-Fei Yuan, Xusheng Wang, Xiaoyang Yang, Abbas Shirinifard Pilehroud, Haitao Pan, Fang Wang, Shondra Pruett-Miller, Kanisha Kavdia, Vishwajeeth Pagala, Yiping Fan, Junmin Peng, Beisi Xu, Jamy C. Peng
Publikováno v:
bioRxiv
53BP1 is a well-established DNA damage repair factor recently shown to regulate gene expression and critically influence tumor suppression and neural development. For gene regulation, how 53BP1 is regulated remains unclear. Here, we showed that 53BP1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef46c874c647dd1d58e4a9e3edf0f42f
https://doi.org/10.1101/2023.05.04.539457
https://doi.org/10.1101/2023.05.04.539457
Autor:
Ping-Chung Chen, Xian Han, Timothy I. Shaw, Yingxue Fu, Huan Sun, Mingming Niu, Zhen Wang, Yun Jiao, Brett J. W. Teubner, Donnie Eddins, Lauren N. Beloate, Bing Bai, Joseph Mertz, Yuxin Li, Ji-Hoon Cho, Xusheng Wang, Zhiping Wu, Danting Liu, Suresh Poudel, Zuo-Fei Yuan, Ariana Mancieri, Jonathan Low, Hyeong-Min Lee, Mary H. Patton, Laurie R. Earls, Elizabeth Stewart, Peter Vogel, Yawei Hui, Shibiao Wan, David A. Bennett, Geidy E. Serrano, Thomas G. Beach, Michael A. Dyer, Richard J. Smeyne, Tudor Moldoveanu, Taosheng Chen, Gang Wu, Stanislav S. Zakharenko, Gang Yu, Junmin Peng
Publikováno v:
Nat Aging
Recent proteome and transcriptome profiling of Alzheimer's disease (AD) brains reveals RNA splicing dysfunction and U1 small nuclear ribonucleoprotein (snRNP) pathology containing U1-70K and its N-terminal 40-KDa fragment (N40K). Here we present a ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc9c90d9fbbcf81944ff50a48af83d57
https://europepmc.org/articles/PMC9833817/
https://europepmc.org/articles/PMC9833817/
Publikováno v:
Proteomics
BACKGROUND: Mass spectrometry (MS)-based proteomic analysis of posttranslational modifications (PTMs) usually requires the pre-enrichment of modified proteins or peptides. However, recent ultra-deep whole proteome profiling generates millions of spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e05406d30ef9620a997d75da02889970
https://europepmc.org/articles/PMC9957936/
https://europepmc.org/articles/PMC9957936/
Autor:
Matteo Trovato, Simone Sidoli, Benjamin A. Garcia, Yekaterina Kori, Zuo-Fei Yuan, Kyung-Min Noh, Peder J. Lund
Publikováno v:
Mol Omics
Histone variants, such as histone H3.3, replace canonical histones within the nucleosome to alter chromatin accessibility and gene expression. Although the biological roles of selected histone post-translational modifications (PTMs) have been extensi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96a291dc33cf7c2725f1217faf3df483
https://europepmc.org/articles/PMC9098674/
https://europepmc.org/articles/PMC9098674/
Autor:
Simone S. Riedel, Alexandra Lenard, Nan Zhu, Taylor Pastuer, Molly C. Kingsley, Tobias Neff, Zuo-Fei Yuan, Tyler Shank, Clara Libbrecht, Hongbo Michael Xie, Kathrin M. Bernt
Publikováno v:
Exp Hematol
Inhibition of the H3K79 histone methyltransferase DOT1L has exhibited encouraging preclinical and early clinical activity in KMT2A (MLL)-rearranged leukemia, supporting the development of combinatorial therapies. Here, we investigated two novel combi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a8ea6a83fdabceab6d33ed97f23482b
https://doi.org/10.1016/j.exphem.2020.04.007
https://doi.org/10.1016/j.exphem.2020.04.007