Zobrazeno 1 - 10
of 94
pro vyhledávání: '"Zunzhen Zhang"'
Publikováno v:
Frontiers in Public Health, Vol 12 (2024)
IntroductionAir flow driven by air-conditioner has a significant impact on the indoor environment, however, the bacterial contamination conditions in the different parts of air-conditioners have not been fully elucidated.MethodsIn this study, we asse
Externí odkaz:
https://doaj.org/article/f657df1abc404f4bb1fe2e3fbe6d14a1
Autor:
Yanhao Lai, Helen Budworth, Jill M. Beaver, Nelson L. S. Chan, Zunzhen Zhang, Cynthia T. McMurray, Yuan Liu
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
The expansion of trinucleotide repeats can have detrimental effects and give rise to a range of human diseases. Here the authors report that the mismatch repair and the base excision repair machinery can operate together to promote expansion during l
Externí odkaz:
https://doaj.org/article/3879ba8a8aee40aca671630c5cc0af1e
Autor:
Yanhao Lai, Jill M Beaver, Karla Lorente, Jonathan Melo, Shyama Ramjagsingh, Irina U Agoulnik, Zunzhen Zhang, Yuan Liu
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e93464 (2014)
Expansion of GAA·TTC repeats within the first intron of the frataxin gene is the cause of Friedreich's ataxia (FRDA), an autosomal recessive neurodegenerative disorder. However, no effective treatment for the disease has been developed as yet. In th
Externí odkaz:
https://doaj.org/article/8542abc33b1d4c1db464a473956f4000
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56960 (2013)
Trinucleotide repeat (TNR) expansions and deletions are associated with human neurodegeneration and cancer. However, their underlying mechanisms remain to be elucidated. Recent studies have demonstrated that CAG repeat expansions can be initiated by
Externí odkaz:
https://doaj.org/article/75773af761414e0c85eb68290d213185
Publikováno v:
The Journal of Antibiotics. 75:341-353
Antibiotic use provides a promising strategy for the treatment of non-alcoholic fatty liver disease (NAFLD) by regulating the gut microbiota composition. Triclosan, a widely used antibiotic, may improve gut microbiome dysbiosis associated with NAFLD
Autor:
Tianhe, Zhao, Donglei, Sun, Wenxiao, Xiong, Jin, Man, Qian, Zhang, Manyu, Zhao, Zunzhen, Zhang
Publikováno v:
Journal of hazardous materials. 445
High-profile RNA epigenetic modification N
Publikováno v:
Journal of Hazardous Materials. 445:130468
Publikováno v:
Cell Biology International. 45:334-344
As the first identified N6 -methyladenosine (m6 A) demethylase, fat mass and obesity-associated (FTO) protein is associated with fatty acid synthase (FASN) and lipid accumulation. However, little is known about the regulatory role of FTO in the expre
Publikováno v:
Biological Trace Element Research. 198:131-141
Oxidative stress is the main mechanism of arsenite toxicity. Long intergenic non-coding RNA regulator of reprogramming is a newly found stress-response long non-coding RNA that is activated in various stress conditions. However, whether long intergen
Autor:
Judy L. Vasquez, Zunzhen Zhang, Irina U. Agoulnik, Yuk-Ching Tse-Dinh, Thirunavukkarasu Annamalai, Yuan Liu, Ruipeng Lei, Yanhao Lai, Manqi Zhang, Zhongliang Jiang
Publikováno v:
Biochimie
Prostate cancer (PCa) progression is characterized by increased expression and transcriptional activity of the androgen receptor (AR). In the advanced stages of prostate cancer, AR significantly upregulates the expression of genes involved in DNA rep