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A multifunctional nanoaggregate‐based system for detection of rheumatoid arthritis via Optoacoustic/NIR‐II fluorescent imaging and therapy via inhibiting JAK‐STAT/NF‐κB/NLRP3 pathways

Autor: Junjie Chen, Longqi Chen, Zunpan She, Fang Zeng, Shuizhu Wu

Publikováno v: Aggregate, Vol 5, Iss 1, Pp n/a-n/a (2024)

Abstract Rheumatoid arthritis (RA) is a debilitating autoimmune disease that causes chronic pain and serious complications, presenting a significant challenge to treat. Promising approaches for treating RA involve signaling pathways modulation and ta

Externí odkaz: https://doaj.org/article/37182640121645688a6cb9a613fc1805

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An NO-responsive probe for detecting acute inflammation using NIR-II fluorescence/optoacoustic imaging

Autor: Zunpan She, Junjie Chen, Lihe Sun, Fang Zeng, Shuizhu Wu

Publikováno v: Chemical Communications. 58:13123-13126

An activatable probe for detecting acute inflammation has been developed. Nitrosation turns electron-donating methylamine into electron-withdrawing methyl-N-nitroso with turn-on NIR-II fluorescence and optoacoustic signals for imaging.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51b1e0b78dd7469b2670bc06b675e5ee
https://doi.org/10.1039/d2cc05386a

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