Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Zunde Wang"'
Autor:
Xiwei Wu, Tibor A. Rauch, Kemp H. Kernstine, Xueyan Zhong, Xinmin Zhang, Sean K. Lau, Arthur D. Riggs, Gerd P. Pfeifer, Zunde Wang
Publikováno v:
Proceedings of the National Academy of Sciences. 104:5527-5532
De novo methylation of CpG islands is a common phenomenon in human cancer, but the mechanisms of cancer-associated DNA methylation are not known. We have used tiling arrays in combination with the methylated CpG island recovery assay to investigate m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f7285843f0edf81c6a3d0b795744d04
https://doi.org/10.1073/pnas.0701059104
https://doi.org/10.1073/pnas.0701059104
Publikováno v:
Expert opinion on medical diagnostics. 1(1)
Alterations in DNA methylation patterns occur in every type of human cancer and are considered a hallmark of malignant transformation. Most notable is the cancer-associated hypermethylation of CpG-rich sequences, the so-called CpG islands, which are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a177fe02088fc45c678d7ec58d2537ab
https://pubmed.ncbi.nlm.nih.gov/23489272
https://pubmed.ncbi.nlm.nih.gov/23489272
Publikováno v:
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. 33(2)
Changes in DNA methylation patterns are an important characteristic of human cancer including lung cancer. In particular, hypermethylation of CpG islands is a signature of malignant progression. Methylated CpG islands are promising diagnostic markers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::550ff2d730071d990114b7c1741cb9ef
https://pubmed.ncbi.nlm.nih.gov/22143938
https://pubmed.ncbi.nlm.nih.gov/22143938
Both Foxp3 + regulatory T cells (Tregs) and antigen-expanded Foxp3 − Tregs play an important role in regulating immune responses as well as in preventing autoimmune diseases and graft rejection. Molecular mechanisms modulating Treg function remain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14ec8a80807d99827c8d49ce0bb1fcf7
https://europepmc.org/articles/PMC3033262/
https://europepmc.org/articles/PMC3033262/
Autor:
Tibor A. Rauch, Arthur D. Riggs, Xueyan Zhong, Zunde Wang, Xiwei Wu, Kemp H. Kernstine, Melody Wang, Gerd P. Pfeifer
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 105(1)
Changes in DNA methylation patterns are an important characteristic of human cancer. Tumors have reduced levels of genomic DNA methylation and contain hypermethylated CpG islands, but the full extent and sequence context of DNA hypomethylation and hy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b795bbe025a2af60d48d58e984f74a9
https://pubmed.ncbi.nlm.nih.gov/18162535
https://pubmed.ncbi.nlm.nih.gov/18162535
Abnormal CpG island methylation occurs during in vitro differentiation of human embryonic stem cells
Publikováno v:
Human molecular genetics. 15(17)
Directed differentiation of human embryonic stem cells (hESCs) into specific somatic cells holds great promise for cell replacement therapies. However, it is unclear if in vitro hESC differentiation causes any epigenetic abnormality such as hypermeth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cc6a3cc01dc8febdebb06ae5efc2d6e
https://pubmed.ncbi.nlm.nih.gov/16870691
https://pubmed.ncbi.nlm.nih.gov/16870691
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 256
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::533d74144592c568337c9651bdd981c2
https://pubmed.ncbi.nlm.nih.gov/15024160
https://pubmed.ncbi.nlm.nih.gov/15024160
Autor:
Somnath Bhattacharyya, Terence E. Martin, Kan Agarwal, F. Gary Toback, Zunde Wang, Margaret M. Walsh-Reitz, C. Thomas Powell
Publikováno v:
American journal of physiology. Gastrointestinal and liver physiology. 285(2)
Human and pig cDNAs for a novel stomach protein, the product of a gene expressed at high levels specifically in cells of the antrum mucosa, have been characterized. The general exon/intron structure of the genomic DNA is conserved in humans and mice.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a0b3b2c06b521ea9ffa3a3bce1985d6
https://pubmed.ncbi.nlm.nih.gov/12851218
https://pubmed.ncbi.nlm.nih.gov/12851218
Bacterial artificial chromosomes (BACs) and P1-derived artificial chromosomes (PACs), with their capacity for large inserts, stability, and lack of chimerism, play important roles in genome mapping and sequencing (Osoegawa et al. 2000). For these rea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca5fffcf105dface0459e379eadac092
https://europepmc.org/articles/PMC311050/
https://europepmc.org/articles/PMC311050/