Zobrazeno 1 - 10
of 94
pro vyhledávání: '"Zun-Ji Ke"'
Autor:
Luyao Wei, Wantao Wang, Junxia Yao, Zhengyu Cui, Zihang Xu, Hanqing Ding, Xiaojun Wu, Deheng Wang, Jia Luo, Zun-Ji Ke
Publikováno v:
Oncogene. 41:4282-4294
Most basal-like breast cancers (BLBCs) are triple-negative breast cancers (TNBCs), which is associated with high malignancy, high rate of recurrence and distant metastasis, and poor prognosis among all types of breast cancer. However, there are curre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b874edaf804cc3be31fd9dd0ac0b6d48
https://doi.org/10.1038/s41388-022-02431-6
https://doi.org/10.1038/s41388-022-02431-6
Background: Neuroinflammation is one of the most important contributing factors for the pathogenesis of Alzheimer’s disease (AD). Cyclooxygenase-1 (COX-1) is distinctly expressed in microglia and involved in microglia activation and neuroinflammati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ea401448c3eaa5eae7256e77fc4025c
https://doi.org/10.21203/rs.3.rs-2522132/v1
https://doi.org/10.21203/rs.3.rs-2522132/v1
Autor:
Zilu Zhu, Hongmiao Zhang, Yusheng Tong, Yuchen Liu, Zhengyu Cui, Ying Mao, Zehan Wu, Deheng Wang, Shize Jiang, Xiang Zou, Zun-Ji Ke, Liang Chen, Yu Guo
Valproic acid (VPA) represents one of the most efficient antiepileptic drugs (AEDs) with either general or focal seizures, but a certain percentage of patients are not recovered or even worse, the mechanism under this phenomenon remains unclear. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c86cef53f51711d5b4ef362a853bf2f1
https://doi.org/10.1101/2021.11.02.21265719
https://doi.org/10.1101/2021.11.02.21265719
Publikováno v:
Science China. Life sciences. 64(7)
Non-steroidal anti-inflammatory drugs (NSAIDs) inhibit prostaglandin (PG) formation by targeting cyclooxygenase (COX) 1 and 2. Long-term use of NSAIDs that selectively inhibit COX2 increases the risk for thrombotic events, cardiac failure, and hypert
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f4c0a6dd5ade02fa9dad028b8e91a8a
https://pubmed.ncbi.nlm.nih.gov/32955658
https://pubmed.ncbi.nlm.nih.gov/32955658
Publikováno v:
Science Bulletin. 62:1593-1601
In vivo monitoring neuropathological changes in Alzheimer's disease (AD) animal model is critical for drug development. Here, by integrating blood-brain barrier penetrable peptide, we have developed a peptide probe which based on angiopep-2. Angiopep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1771d7a637c16adc98b69d53f66bf7e3
https://doi.org/10.1016/j.scib.2017.11.005
https://doi.org/10.1016/j.scib.2017.11.005
Autor:
Jia Luo, Jacqueline A. Frank, Haiping Wang, Fanmuyi Yang, Zun-Ji Ke, Zhenhua Ren, Siying Wang, Xin Wang, Mei Xu
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1863:2746-2761
Ethanol exposure during development causes fetal alcohol spectrum disorders (FASD). A large body of evidence shows that ethanol produces multiple abnormalities in the developing central nervous system (CNS), such as smaller brain size, reduced volume
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03b97305d227ace19cc31d24c71a0589
https://doi.org/10.1016/j.bbadis.2017.07.035
https://doi.org/10.1016/j.bbadis.2017.07.035
Publikováno v:
Toxicology and Applied Pharmacology. 320:26-31
Thiamine (vitamin B1) deficiency (TD) plays a major role in the etiology of Wernicke's encephalopathy (WE) which is a severe neurological disorder. TD induces selective neuronal cell death, neuroinflammation, endoplasmic reticulum (ER) stress and oxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2885cd7046902c2f9cfe8787b3c6e330
https://doi.org/10.1016/j.taap.2017.02.009
https://doi.org/10.1016/j.taap.2017.02.009
Autor:
Qing Shi, Zhenzhen Quan, Yan Yan, Da Song, Chunjian Wang, Heao Zhang, Qinghu Yang, Yiran Lang, Hong Qing, Yili Wu, Zun-Ji Ke, Deheng Wang, Tianyi Yan, Zhe Wang, Zhen Xie, Yanhui Li, Talal Jamil Qazi, Juan Zhao, Yuchen Liu, Huang Tao
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
The hippocampal CA3 contributes to spatial working memory (SWM), but which stage of SWM the CA3 neurons act on and whether the lateralization of CA3 function occurs in SWM is also unknown. Here, we reveal increased neural activity in both sample and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09e213d588efa2096dee73b304b44a11
https://pubmed.ncbi.nlm.nih.gov/32518226
https://pubmed.ncbi.nlm.nih.gov/32518226
Publikováno v:
Molecular Neurobiology. 54:5440-5448
Thiamine (vitamin B1) is an essential nutrient and indispensable for normal growth and development of the organism due to its multilateral participation in key biochemical and physiological processes. Humans must obtain thiamine from their diet since
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae2caf0272b96b47afde1d0b13299bff
https://doi.org/10.1007/s12035-016-0079-9
https://doi.org/10.1007/s12035-016-0079-9
Publikováno v:
Oncotarget
// Zhenhua Ren 1,2 , Xin Wang 2 , Mei Xu 2 , Fanmuyi Yang 2 , Jacqueline A. Frank 2 , Zun-ji Ke 3 and Jia Luo 2,3 1 Department of Anatomy, School of Basic Medicine, Anhui Medical University, Hefei, China 2 Department of Pharmacology and Nutritional S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98739ff3019eed588f9e8f8eb76ba4aa
https://doi.org/10.18632/oncotarget.11103
https://doi.org/10.18632/oncotarget.11103