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Akademický článek

Methylation of N6 adenosine‐related long noncoding RNA: effects on prognosis and treatment in ‘driver‐gene‐negative’ lung adenocarcinoma

Autor: Hao‐Shuai Yang, He‐Yuan Cai, Shi‐Chao Shan, Ting‐Fei Chen, Jian‐Yong Zou, Maimaiti Abudurufu, Hong‐He Luo, Yi‐Yan Lei, Zun‐Fu Ke, Ying Zhu

Publikováno v: Molecular Oncology, Vol 17, Iss 2, Pp 365-377 (2023)

The improvement of treatment for patients with ‘driver‐gene‐negative’ lung adenocarcinoma (LUAD) remains a critical problem to be solved. We aimed to explore the role of methylation of N6 adenosine (m6A)‐related long noncoding RNA (lncRNA)

Externí odkaz: https://doaj.org/article/e6889ac32332414a93f83ba9ee9e3436

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Akademický článek

Three-dimensional nanostructured substrates enable dynamic detection of ALK-rearrangement in circulating tumor cells from treatment-naive patients with stage III/IV lung adenocarcinoma

Autor: Weiling He, Di Xu, Zhuo Wang, Hui Wu, Xianhong Xiang, Bing Tang, Wenting Jiang, Yongmei Cui, Han Wang, Neng Jiang, Yu Sun, Yangshan Chen, Shuhua Li, Minzhi Hou, Yang Zhang, Liantang Wang, Zun-fu Ke

Publikováno v: Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-13 (2019)

Abstract Background Circulating tumor cells (CTC) shows great prospect to realize precision medicine in cancer patients. Methods We developed the NanoVelcro Chip integrating three functional mechanisms. NanoVelcro CTC capture efficiency was tested in

Externí odkaz: https://doaj.org/article/28239f69a35b42aa83356c705a011211

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Akademický článek

GOLPH3 Overexpression is Closely Correlated with Poor Prognosis in Human Non-Small Cell Lung Cancer and Mediates its Metastasis Through Upregulating MMP-2 and MMP-9

Autor: Ran Wang, Zun-fu Ke, Fen Wang, Wen-hui Zhang, Yue-feng Wang, Shu-hua Li, Lian-tang Wang

Publikováno v: Cellular Physiology and Biochemistry, Vol 35, Iss 3, Pp 969-982 (2015)

Background/Aims: Golgi phosphoprotein 3 (GOLPH3) is a newly reported oncogene that plays a significant role in regulating cell growth. Recent research has shown that overexpression of GOLPH3 is correlated with patient survival and M classification in

Externí odkaz: https://doaj.org/article/baa5fe1cc4394d059c3c78440b8f02c3

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Methylation of N6 adenosine‐related long noncoding RNA : effects on prognosis and treatment in ‘driver‐gene‐negative’ lung adenocarcinoma

Autor: Hao‐Shuai Yang, He‐Yuan Cai, Shi‐Chao Shan, Ting‐Fei Chen, Jian‐Yong Zou, Maimaiti Abudurufu, Hong‐He Luo, Yi‐Yan Lei, Zun‐Fu Ke, Ying Zhu

Publikováno v: Molecular Oncology. 17:365-377

The improvement of treatment for patients with 'driver-gene-negative' lung adenocarcinoma (LUAD) remains a critical problem to be solved. We aimed to explore the role of methylation of N6 adenosine (m6A)-related long noncoding RNA (lncRNA) in stratif

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::695410a4cd5388da70990f939a36c301
https://doi.org/10.1002/1878-0261.13323

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A radiomics nomogram prediction for survival of patients with 'driver gene-negative' lung adenocarcinomas (LUAD)

Autor: Qi-Kun Guo, Hao-Shuai Yang, Shi-Chao Shan, Dan-Dan Chang, Li-Jie Qiu, Hong-He Luo, He-Ping Li, Zun-Fu Ke, Ying Zhu

Publikováno v: La radiologia medica.

Background To study the role of computed tomography (CT)-derived radiomics features and clinical characteristics on the prognosis of “driver gene-negative” lung adenocarcinoma (LUAD) and to explore the potential molecular biological which may be

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c183dc15e1af66337f705b722a1c5fb8
https://doi.org/10.1007/s11547-023-01643-4

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Prognostic Nomogram to Predict the Overall Survival of Patients with 'driver-gene-negative' Lung Adenocarcinoma (LUAD) and Its’ Biological Basis Deciphering

Autor: Honghe Luo, Zun-Fu Ke, Ying Zhu, Zhenguo Liu, Dan-Dan Chang, Hao-Shuai Yang, Shi-Chao Shan, Yi-Yan Lei, Qi-Kun Guo

Objectives: Assessing the prognosis of patients with “driver-gene-negative” lung adenocarcinoma (LUAD patients negative for EGFR, KRAS, BRAF, HER2, MET, ALK, RET and ROS1 were identified as “driver-gene-negative”) is of significant clinical i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::906391e9fa2776107e6a3c85abd80c3a
https://doi.org/10.21203/rs.3.rs-933879/v1

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Development and Validation of a Deep Learning Model for Preoperative Screening of Myasthenia Gravis in Patients with Thymoma based on CT Images

Autor: Zhenguo Liu, Xi Wu, Lei Yang, Jiechao Ma, Rongguo Zhang, Xi Tian, Kefeng Wang, Zun-Fu Ke, Yujie Yuan, Xiao-Yu Yang, Ming-Hui Wang, Ying Zhu

Objectives: Thymoma-associated myasthenia gravis (TAMG) is the most common paraneoplastic syndromeof thymoma. The screening of TAMG before thymoma resection is required to avoid severe perioperative complications, especiallyrespiratory failure. Herei

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::40cb62d8aa9b47a87207926c2f42f9d6
https://doi.org/10.21203/rs.3.rs-26909/v1

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