Výsledky vyhledávání - "Zumrut Kocak"

Modulation of oxidative–nitrosative stress and inflammatory response by rapamycin in target and distant organs in rats exposed to hindlimb ischemia–reperfusion: the role of mammalian target of rapamycin

Autor: Seyhan Sahan-Firat, Senay Balci, Özden Vezir, Lulufer Tamer-Gumus, Bahar Tunctan, Meryem Temiz-Resitoglu, Kafait U. Malik, Zumrut Kocak, Demet Sinem Guden, Nehir Sucu

Publikováno v: Canadian Journal of Physiology and Pharmacology. 97:1193-1203

Mammalian target of rapamycin (mTOR) has been recognized with potential immunomodulatory properties playing an important role in various physiopathological processes including ischemia–reperfusion (I/R) injury. I/R injury stimulate reactive oxygen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac436769f8ee2eab3293a06a07ba755e
https://doi.org/10.1139/cjpp-2019-0394

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Protection by mTOR Inhibition on Zymosan-Induced Systemic Inflammatory Response and Oxidative/Nitrosative Stress: Contribution of mTOR/MEK1/ERK1/2/IKKβ/IκB-α/NF-κB Signalling Pathway

Autor: Zumrut Kocak, Bahar Tunctan, Demet Sinem Guden, Sefika Pinar Kucukkavruk, Ayse Nihal Sari, Kafait U. Malik, Seyhan Sahan-Firat, Meryem Temiz-Resitoglu

Publikováno v: Inflammation. 41(1)

Mammalian target of rapamycin (mTOR), a serine/threonine kinase regulate variety of cellular functions including cell growth, differentiation, cell survival, metabolism, and stress response, is now appreciated to be a central regulator of immune resp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f45f4b112adf5ad0debc002dc216b39a
https://pubmed.ncbi.nlm.nih.gov/29110153

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