Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Zuming Lin"'
Publikováno v:
ChemBioChem. 22:996-1000
Chiral cyanohydrins are useful intermediates in the pharmaceutical and agricultural industries. In nature, hydroxynitrile lyases (HNLs) are a kind of elegant tool for enantioselective hydrocyanation of carbonyl compounds. However, currently available
Publikováno v:
Chinese Journal of Chemistry. 38:725-736
Publikováno v:
ACS Catalysis. 10:5757-5763
The chiral vicinal C–O/C–N bifunctional groups generated from enzymatic hydrocyanation represents a useful methodology. However, construction of the pharmacophore of β2-adrenoreceptor agonists with...
Publikováno v:
Angewandte Chemie. 130:16432-16436
Efficient access to medicinally significant natural products is an essential basis for the development of pharmaceuticals. The limited availability of marine natural products impedes broad biological evaluation. Despite several elegant syntheses of (
Publikováno v:
Angewandte Chemie International Edition. 55:6280-6284
A stereodivergent strategy enabled by bioinspired oxa-Michael cyclization was developed for the synthesis of functionalized tetrahydropyrans on the basis of the inherent symmetry in 1,3-diols, the symmetries of which were tunable by stereoselective h
Publikováno v:
Tetrahedron Letters. 57:603-606
A highly efficient lipase AK-catalyzed direct kinetic resolution of a variety of α-allenic alcohols was developed. With the complementary to previous studies, the current reaction system is effective on a broad range of substituents (R1) at C(1), su
Publikováno v:
Angewandte Chemie International Edition. 58:4431-4431
Publikováno v:
Angewandte Chemie. 131:4477-4477
Publikováno v:
ChemInform. 47
A stereodivergent strategy enabled by bioinspired oxa-Michael cyclization was developed for the synthesis of functionalized tetrahydropyrans on the basis of the inherent symmetry in 1,3-diols, the symmetries of which were tunable by stereoselective h
Autor:
Ran Hong, Zuming Lin, Junzeng Dai, Lin Yang, Donghu Bai, Sha-Hua Huang, Meng-Yuan Huang, Xueshun Jia
Publikováno v:
ChemInform. 44
The synthesis of racemic Tapentadol (V) and its diastereoisomers, both bearing two tertiary stereogenic carbon centers, is disclosed.