Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Zumer Naeem"'
Autor:
Sebastian Kempf, Rüdiger Popp, Zumer Naeem, Timo Frömel, Ilka Wittig, Stephan Klatt, Ingrid Fleming
Publikováno v:
Cells, Vol 13, Iss 17, p 1429 (2024)
The pericyte coverage of microvessels is altered in metabolic diseases, but the mechanisms regulating pericyte–endothelial cell communication remain unclear. This study investigated the formation and function of pericyte tunneling nanotubes (TNTs)
Externí odkaz:
https://doaj.org/article/2c841dc97e5d4006976d4077d26de002
Autor:
Zumer Naeem, Sven Zukunft, Arnaud Huard, Jiong Hu, Bruce D. Hammock, Andreas Weigert, Timo Frömel, Ingrid Fleming
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 171, Iss , Pp 116127- (2024)
The lipid content of skin plays a determinant role in its barrier function with a particularly important role attributed to linoleic acid and its derivatives. Here we explored the consequences of interfering with the soluble epoxide hydrolase (sEH) o
Externí odkaz:
https://doaj.org/article/007633b0f61941f286a9a83ad9234b49
Autor:
Anne-Kathrin Knuth, Arnaud Huard, Zumer Naeem, Peter Rappl, Rebekka Bauer, Ana Carolina Mota, Tobias Schmid, Ingrid Fleming, Bernhard Brüne, Simone Fulda, Andreas Weigert
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 5, p 2230 (2021)
The interaction of macrophages with apoptotic cells is required for efficient resolution of inflammation. While apoptotic cell removal prevents inflammation due to secondary necrosis, it also alters the macrophage phenotype to hinder further inflamma
Externí odkaz:
https://doaj.org/article/d60433b47621489fbb618b53a5f47131
Autor:
Jan Heering, Victor Hernandez-Olmos, Niklas Ildefeld, Ting Liu, Anja Kaiser, Zumer Naeem, Timo Frömel, Ingrid Fleming, Dieter Steinhilber, Ewgenij Proschak
Publikováno v:
Journal of Medicinal Chemistry. 65:2023-2034
The leukotriene B4 receptor 2 (BLT2) is a G-protein coupled receptor activated by 12(S)-hydroxyheptadeca-5Z,8E,10E-trienoic acid (12-HHT), which has been proposed as a promising therapeutic target for diabetic wound healing and gastrointestinal lesio
Autor:
Zumer Naeem, Sven Zukunft, Stephan Günther, Stefan Liebner, Andreas Weigert, Bruce D. Hammock, Timo Frömel, Ingrid Fleming
Publikováno v:
Pflugers Archiv : European journal of physiology, vol 474, iss 9
Polyunsaturated fatty acids (PUFAs) are used as traditional remedies to treat hair loss, but the mechanisms underlying their beneficial effects are not well understood. Here, we explored the role of PUFA metabolites generated by the cytochrome P450/s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c329f295d7cca30dfe07b1ceca2c22e
https://escholarship.org/uc/item/1321j30h
https://escholarship.org/uc/item/1321j30h
Publikováno v:
Pharmacology & Therapeutics. 234:108049
Cytochrome P450 (CYP) enzymes are frequently referred to as the third pathway for the metabolism of arachidonic acid. While it is true that these enzymes generate arachidonic acid epoxides i.e. the epoxyeicosatrienoic acids (EETs), they are able to a
Autor:
Alexandra Geyer, Eiman Elwakeel, Ilka Wittig, Ingrid Fleming, Andreas Weigert, Bernhard Brüne, Timo Frömel, Juliana Heidler, Zumer Naeem, Hebatullah Laban, Sven Zukunft, Rushendhiran Kesavan, Rüdiger Popp
Publikováno v:
Proc Natl Acad Sci U S A
Arachidonic acid epoxides generated by cytochrome P450 (CYP) enzymes have been linked to increased tumor growth and metastasis, largely on the basis of overexpression studies and the application of exogenous epoxides. Here we studied tumor growth and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca951f924d35e9a5b6fc02782fbe8699
https://publica.fraunhofer.de/handle/publica/267043
https://publica.fraunhofer.de/handle/publica/267043