In vitro and in vivo activity of GT-1, a novel siderophore cephalosporin, and GT-055, a broad-spectrum β-lactamase inhibitor, against biothreat and ESKAPE pathogens.

Autor: Halasohoris SA; US Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD, USA., Scarff JM; US Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD, USA., Pysz LM; US Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD, USA., Lembirik S; US Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD, USA., Lemmon MM; US Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD, USA., Biek D; Geom Therapeutics Inc, San Diego, CA, USA., Hannah B; Geom Therapeutics Inc, San Diego, CA, USA., Zumbrun SD; US Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD, USA., Panchal RG; US Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD, USA. rekha.g.panchal.civ@mail.mil.

Publikováno v: The Journal of antibiotics [J Antibiot (Tokyo)] 2021 Dec; Vol. 74 (12), pp. 884-892. Date of Electronic Publication: 2021 Sep 14.

In Vitro and In Vivo Characterization of Tebipenem (TBP), an Orally Active Carbapenem, against Biothreat Pathogens.

Autor: Clayton NP; Spero Therapeutics Inc., Cambridge, MA nclayton@sperotherapeutics.com., Jain A; Spero Therapeutics Inc., Cambridge, MA., Halasohoris SA; US Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD., Pysz LM; US Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD., Lembirik S; US Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD., Zumbrun SD; US Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD., Kane CD; US Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD., Hackett MJ; Battelle Memorial Institute, Columbus, OH., Pfefferle D; Battelle Memorial Institute, Columbus, OH., Smiley MA; Battelle Memorial Institute, Columbus, OH., Anderson MS; Battelle Memorial Institute, Columbus, OH., Heine H; Institute for Therapeutic Innovation, Department of Medicine, University of Florida, Orlando, FL., Meister GT; Battelle Memorial Institute, Columbus, OH., Pucci MJ; Spero Therapeutics Inc., Cambridge, MA.

Publikováno v: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2021 May 01; Vol. 65 (5). Date of Electronic Publication: 2021 Feb 16.

GC-072: A Novel Therapeutic Candidate for Oral Treatment of Melioidosis and Infections Caused by Select Biothreat Pathogens.

Autor: Shearer JD; Emergent BioSolutions, Gaithersburg, MD., Saylor ML; Emergent BioSolutions, Gaithersburg, MD., Butler CM; Emergent BioSolutions, Gaithersburg, MD., Treston AM; Emergent BioSolutions, Gaithersburg, MD., Heine HS; Institute for Therapeutic Innovation, University of Florida, College of Medicine, Orlando, FL., Chirakul S; Emerging Pathogens Institute, University of Florida, College of Medicine, Gainesville, FL., Schweizer HP; Institute for Therapeutic Innovation, University of Florida, College of Medicine, Orlando, FL.; Emerging Pathogens Institute, University of Florida, College of Medicine, Gainesville, FL., Louie A; Institute for Therapeutic Innovation, University of Florida, College of Medicine, Orlando, FL., Drusano GL; Institute for Therapeutic Innovation, University of Florida, College of Medicine, Orlando, FL., Zumbrun SD; United States Army Medical Research Institute of Infectious Diseases, Frederick MD., Warfield KL; Emergent BioSolutions, Gaithersburg, MD warfieldk@ebsi.com.

Publikováno v: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2019 Sep 09; Vol. 63 (12). Date of Electronic Publication: 2019 Sep 23.

Synergy Between Proline-Rich Antimicrobial Peptides and Small Molecule Antibiotics Against Selected Gram-Negative Pathogens in vitro and in vivo .

Autor: Otvos L Jr; OLPE, LLC, Audubon, PA, United States.; Institute of Medical Microbiology, Semmelweis University, Budapest, Hungary.; Arrevus, Inc., Raleigh, NC, United States., Ostorhazi E; Institute of Medical Microbiology, Semmelweis University, Budapest, Hungary., Szabo D; Institute of Medical Microbiology, Semmelweis University, Budapest, Hungary., Zumbrun SD; Bacteriology Division, United States Army Medical Research Institute of Infectious Diseases Fort Detrick, MD, United States., Miller LL; Bacteriology Division, United States Army Medical Research Institute of Infectious Diseases Fort Detrick, MD, United States., Halasohoris SA; Bacteriology Division, United States Army Medical Research Institute of Infectious Diseases Fort Detrick, MD, United States., Desai PD; Bacteriology Division, United States Army Medical Research Institute of Infectious Diseases Fort Detrick, MD, United States., Int Veldt SM; Bacteriology Division, United States Army Medical Research Institute of Infectious Diseases Fort Detrick, MD, United States., Kraus CN; Arrevus, Inc., Raleigh, NC, United States.

Publikováno v: Frontiers in chemistry [Front Chem] 2018 Aug 14; Vol. 6, pp. 309. Date of Electronic Publication: 2018 Aug 14 (Print Publication: 2018).

Gender and age differences in growth factor concentrations from platelet-rich plasma in adults.

Autor: Evanson JR; Department of Orthopaedics, Dwight D. Eisenhower Army Medical Center, 300 Hospital Road, Fort Gordon, GA 30905., Guyton MK; Department of Clinical Investigation, 38th Avenue, 7th Street, Building 38705, Fort Gordon, GA 30905., Oliver DL; Department of Orthopaedics, Dwight D. Eisenhower Army Medical Center, 300 Hospital Road, Fort Gordon, GA 30905., Hire JM; Department of Orthopaedics, Dwight D. Eisenhower Army Medical Center, 300 Hospital Road, Fort Gordon, GA 30905., Topolski RL; Department of Clinical Investigation, 38th Avenue, 7th Street, Building 38705, Fort Gordon, GA 30905., Zumbrun SD; Department of Clinical Investigation, 38th Avenue, 7th Street, Building 38705, Fort Gordon, GA 30905., McPherson JC; Department of Clinical Investigation, 38th Avenue, 7th Street, Building 38705, Fort Gordon, GA 30905., Bojescul JA; Department of Orthopaedics, Dwight D. Eisenhower Army Medical Center, 300 Hospital Road, Fort Gordon, GA 30905.

Publikováno v: Military medicine [Mil Med] 2014 Jul; Vol. 179 (7), pp. 799-805.