Synthesis, in vitro Antileishmanial Efficacy and Hit/Lead Identification of Nitrofurantoin-Triazole Hybrids.

Autor: Zuma NH; Centre of Excellence for Pharmaceutical Sciences (Pharmacen), Faculty of Health Sciences, North-West University, 11 Hoffmann Street, Potchefstroom, 2520, South Africa., Aucamp J; Centre of Excellence for Pharmaceutical Sciences (Pharmacen), Faculty of Health Sciences, North-West University, 11 Hoffmann Street, Potchefstroom, 2520, South Africa., Viljoen M; School of Pharmacy, Faculty of Health Sciences, North-West University, 11 Hoffmann Street, Potchefstroom, 2520, South Africa., N'Da DD; Centre of Excellence for Pharmaceutical Sciences (Pharmacen), Faculty of Health Sciences, North-West University, 11 Hoffmann Street, Potchefstroom, 2520, South Africa.

Publikováno v: ChemMedChem [ChemMedChem] 2022 May 18; Vol. 17 (10), pp. e202200023. Date of Electronic Publication: 2022 May 02.

Synthesis and in vitro antileishmanial efficacy of novel quinazolinone derivatives.

Autor: Prinsloo IF; Pharmaceutical Chemistry, School of Pharmacy, North-West University, Potchefstroom, South Africa., Zuma NH; Centre of Excellence for Pharmaceutical Sciences, North-West University, Potchefstroom, South Africa., Aucamp J; Centre of Excellence for Pharmaceutical Sciences, North-West University, Potchefstroom, South Africa., N'Da DD; Centre of Excellence for Pharmaceutical Sciences, North-West University, Potchefstroom, South Africa.

Publikováno v: Chemical biology & drug design [Chem Biol Drug Des] 2021 Feb; Vol. 97 (2), pp. 383-398. Date of Electronic Publication: 2020 Sep 20.

Single-step synthesis and in vitro anti-mycobacterial activity of novel nitrofurantoin analogues.

Autor: Zuma NH; Centre of Excellence for Pharmaceutical Sciences, North-West University, Potchefstroom 2520, South Africa., Smit FJ; Centre of Excellence for Pharmaceutical Sciences, North-West University, Potchefstroom 2520, South Africa., Seldon R; SAMRC Drug Discovery and Development Research Unit, University of Cape Town, Cape Town 7700, South Africa., Aucamp J; Centre of Excellence for Pharmaceutical Sciences, North-West University, Potchefstroom 2520, South Africa., Jordaan A; SAMRC/NHLS/UCT Molecular Mycobacteriology Research Unit, Department of Pathology and Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, 7925, South Africa., Warner DF; SAMRC/NHLS/UCT Molecular Mycobacteriology Research Unit, Department of Pathology and Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, 7925, South Africa; Wellcome Centre for Clinical Infectious Diseases Research in Africa, University of Cape Town, Cape Town 7925, South Africa., N'Da DD; Centre of Excellence for Pharmaceutical Sciences, North-West University, Potchefstroom 2520, South Africa. Electronic address: david.nda@nwu.ac.za.

Publikováno v: Bioorganic chemistry [Bioorg Chem] 2020 Mar; Vol. 96, pp. 103587. Date of Electronic Publication: 2020 Jan 16.

Synthesis and biological evaluation of a series of non-hemiacetal ester derivatives of artemisinin.

Autor: Zuma NH; Centre of Excellence for Pharmaceutical Sciences, North-West University, Potchefstroom 2520, South Africa., Smit FJ; Centre of Excellence for Pharmaceutical Sciences, North-West University, Potchefstroom 2520, South Africa., de Kock C; Division of Clinical Pharmacology, University of Cape Town, Groote Schuur Hospital, Observatory 7925, South Africa., Combrinck J; Division of Clinical Pharmacology, University of Cape Town, Groote Schuur Hospital, Observatory 7925, South Africa., Smith PJ; Division of Clinical Pharmacology, University of Cape Town, Groote Schuur Hospital, Observatory 7925, South Africa., N'Da DD; Centre of Excellence for Pharmaceutical Sciences, North-West University, Potchefstroom 2520, South Africa. Electronic address: david.nda@nwu.ac.za.

Publikováno v: European journal of medicinal chemistry [Eur J Med Chem] 2016 Oct 21; Vol. 122, pp. 635-646. Date of Electronic Publication: 2016 Jul 14.