Zobrazeno 1 - 10 of 15 pro vyhledávání: '"Zulrahman Erlangga"'
1
Akademický článek
The effect of prolonged intermittent fasting on autophagy, inflammasome and senescence genes expressions: An exploratory study in healthy young males
Autor: Zulrahman Erlangga, Samaneh Khosandam Ghashang, Imad Hamdan, Anette Melk, Christoph Gutenbrunner, Boya Nugraha
Publikováno v: Human Nutrition & Metabolism, Vol 32, Iss , Pp 200189- (2023)
Intermittent fasting (IF) has been associated with longevity and healthspan through autophagy and reduction of inflammation activity. The senescence process is linked with autophagy activity and determines the organ age as chronological age. The effe
Externí odkaz: https://doaj.org/article/1ed2ff3f54934660bd544d711bb7cfdf
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2
Akademický článek
The mTOR inhibitor Rapamycin protects from premature cellular senescence early after experimental kidney transplantation
Autor: Uwe Hoff, Denise Markmann, Daniela Thurn-Valassina, Melina Nieminen-Kelhä, Zulrahman Erlangga, Jessica Schmitz, Jan Hinrich Bräsen, Klemens Budde, Anette Melk, Björn Hegner
Publikováno v: PLoS ONE, Vol 17, Iss 4 (2022)
Interstitial fibrosis and tubular atrophy, a major cause of kidney allograft dysfunction, has been linked to premature cellular senescence. The mTOR inhibitor Rapamycin protects from senescence in experimental models, but its antiproliferative proper
Externí odkaz: https://doaj.org/article/58d44479abe14d3582555c754b346f0c
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3
Induction of ferroptosis selectively eliminates senescent tubular cells
Autor: Chieh M. Liao, Vera C. Wulfmeyer, Rongjun Chen, Zulrahman Erlangga, Julius Sinning, Anne von Mässenhausen, Inga Sörensen-Zender, Kristina Beer, Sibylle von Vietinghoff, Hermann Haller, Andreas Linkermann, Anette Melk, Roland Schmitt
Publikováno v: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant SurgeonsREFERENCES. 22(9)
The accumulation of senescent cells is an important contributor to kidney aging, chronic renal disease, and poor outcome after kidney transplantation. Approaches to eliminate senescent cells with senolytic compounds have been proposed as novel strate
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58027506eacbc906784cf205f874cecd
https://pubmed.ncbi.nlm.nih.gov/35607817
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6
The mTOR inhibitor Rapamycin protects from premature cellular senescence early after experimental kidney transplantation
Autor: Uwe, Hoff, Denise, Markmann, Daniela, Thurn-Valassina, Melina, Nieminen-Kelhä, Zulrahman, Erlangga, Jessica, Schmitz, Jan Hinrich, Bräsen, Klemens, Budde, Anette, Melk, Björn, Hegner
Interstitial fibrosis and tubular atrophy, a major cause of kidney allograft dysfunction, has been linked to premature cellular senescence. The mTOR inhibitor Rapamycin protects from senescence in experimental models, but its antiproliferative proper
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b49428ea3946e93bbcc951614d644cce
https://doi.org/10.1371/journal.pone.0266319
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7
Generation of focal mutations and large genomic deletions in the pancreas using inducible in vivo genome editing
Autor: Michael P. Manns, Lukas E. Dow, Anna Saborowski, Fatemeh Emamgholi, Florian Kühnel, Björn Hartleben, Amrendra Mishra, Scott W. Lowe, Norman Woller, Ulrike Teichmann, Michael Saborowski, Kristian Unger, Katharina Wolff, Zulrahman Erlangga, Michael Kessel, Arndt Vogel
Publikováno v: Carcinogenesis 41, 334-344 (2020)
Carcinogenesis
Beyond the nearly uniform presence of KRAS mutations, pancreatic cancer is increasingly recognized as a heterogeneous disease. Preclinical in vivo model systems exist, but with the advent of precision oncology, murine models with enhanced genetic fle
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7073c1937e3853afa6b264a77069b36
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=56640
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8
Potent Antitumor Activity of Liposomal Irinotecan in an Organoid- and CRISPR-Cas9-Based Murine Model of Gallbladder Cancer
Autor: Tanja Poth, Arndt Vogel, Katharina Wolff, Anna Saborowski, Michael Saborowski, Alexander Peltzer, Norman Woller, Michael P. Manns, Sven Nahnsen, Steffi Spielberg, Kai Timrott, Zulrahman Erlangga, Florian Kühnel
Publikováno v: Cancers
Volume 11
Issue 12
Gallbladder cancer is associated with a dismal prognosis, and accurate in vivo models will be elemental to improve our understanding of this deadly disease and develop better treatment options. We have generated a transplantation-based murine model f
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb46ae65c46f808b2d9cc588349f3a21
http://europepmc.org/articles/PMC6966678
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