Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Zully Pedrozo"'
Autor:
Nicolas Herrera-Zelada, Úrsula Zúñiga-Cuevas, Andrés Ramírez-Reyes, Ignacio Norambuena-Soto, Leslye Venegas-Zamora, Mayarling F. Troncoso, Alejandra Hernández, Gina Sánchez, Zully Pedrozo, Sergio Lavandero, Jaime A. Riquelme
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Small extracellular vesicles are nanosized vesicles (30–200 nm) that can ferry proteins, nucleic acids, and lipids between cells and therefore, have significant potential as biomarkers, drug delivery tools or therapeutic agents. SEVs of endothelial
Externí odkaz:
https://doaj.org/article/831361ba889740838558f0ef5b568c11
Autor:
Leslye Venegas-Zamora, Francisco Bravo-Acuña, Francisco Sigcho, Wileidy Gomez, José Bustamante-Salazar, Zully Pedrozo, Valentina Parra
Publikováno v:
Frontiers in Genetics, Vol 12 (2022)
Down syndrome (DS) is a genetic disorder caused by a trisomy of the human chromosome 21 (Hsa21). Overexpression of Hsa21 genes that encode proteins and non-coding RNAs (ncRNAs) can disrupt several cellular functions and biological processes, especial
Externí odkaz:
https://doaj.org/article/0f7363c39bb448fa834331531b96ebf7
Autor:
Magda C. Díaz-Vesga, Raúl Flores-Vergara, Jaime A. Riquelme, Marcelo Llancaqueo, Gina Sánchez, Cecilia Vergara, Luis Michea, Paulina Donoso, Andrew F. G. Quest, Ivonne Olmedo, Zully Pedrozo
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 1, p 667 (2022)
Cardiomyopathy is commonly observed in patients with autosomal dominant polycystic kidney disease (ADPKD), even when they have normal renal function and arterial pressure. The role of cardiomyocyte polycystin-1 (PC1) in cardiovascular pathophysiology
Externí odkaz:
https://doaj.org/article/7cd63e0bcbc3426fb8e4ebe377f29024
Autor:
Raúl Flores-Vergara, Ivonne Olmedo, Pablo Aránguiz, Jaime Andrés Riquelme, Raúl Vivar, Zully Pedrozo
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Communication between cells is a foundational concept for understanding the physiology and pathology of biological systems. Paracrine/autocrine signaling, direct cell-to-cell interplay, and extracellular matrix interactions are three types of cell co
Externí odkaz:
https://doaj.org/article/f403dbe0f8c440d5b3178a1691f9e95a
Autor:
Carolina Fernández, Natalia Torrealba, Francisco Altamirano, Valeria Garrido-Moreno, César Vásquez-Trincado, Raúl Flores-Vergara, Camila López-Crisosto, María Paz Ocaranza, Mario Chiong, Zully Pedrozo, Sergio Lavandero
Publikováno v:
PLoS ONE, Vol 16, Iss 8, p e0255452 (2021)
Cardiac hypertrophy is the result of responses to various physiological or pathological stimuli. Recently, we showed that polycystin-1 participates in cardiomyocyte hypertrophy elicited by pressure overload and mechanical stress. Interestingly, polyc
Externí odkaz:
https://doaj.org/article/282852eddbe64e25877af76197d62e17
Autor:
Gina Sánchez, Stefanie Chalmers, Xavier Ahumada, Luis Montecinos, Ivonne Olmedo, Veronica Eisner, Ana Riveros, Marcelo J Kogan, Sergio Lavandero, Zully Pedrozo, Paulina Donoso
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0233591 (2020)
The heart is critically dependent on mitochondrial respiration for energy supply. Ischemia decreases oxygen availability, with catastrophic consequences for cellular energy systems. After a few minutes of ischemia, the mitochondrial respiratory chain
Externí odkaz:
https://doaj.org/article/0e94b3db9c084af18eb0bd5f8e0ffb42
Autor:
Sabrina Sepúlveda-Rivas, Matías S. Leal, Zully Pedrozo, Marcelo J. Kogan, María Paz Ocaranza, Javier O. Morales
Publikováno v:
Pharmaceutics, Vol 13, Iss 6, p 822 (2021)
Ang-(1-9) peptide is a bioactive vasodilator peptide that prevents cardiomyocyte hypertrophy in vitro and in vivo as well as lowers blood pressure and pathological cardiovascular remodeling; however, it has a reduced half-life in circulation, requiri
Externí odkaz:
https://doaj.org/article/4d48c4ba122d4e159234a8b26ac613d3
Autor:
Gina Sanchez, Daniela Berrios, Ivonne Olmedo, Javier Pezoa, Jaime A Riquelme, Luis Montecinos, Zully Pedrozo, Paulina Donoso
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0161068 (2016)
Inhibitors of the ubiquitin-proteasome system improve hemodynamic parameters and decrease the infarct size after ischemia reperfusion. The molecular basis of this protection is not fully understood since most available data report inhibition of the 2
Externí odkaz:
https://doaj.org/article/caec7c5c58cc4652beec5eac6b64dcf0
Autor:
Catalina Nachtigall, Natalia Olivares, Paula Fierro, Bruno Manríquez, Antonia Rojas, Magdalena González, Magda C. Díaz-Vesga, Zully Pedrozo
Publikováno v:
Revista chilena de cardiología. 40:203-210
Publikováno v:
Journal of Molecular and Cellular Cardiology. 141:65-69
Cardiac hypertrophy is an adaptive response to manage an excessive cardiac workload and maintain normal cardiac function. However, sustained hypertrophy leads to cardiomyopathy, cardiac failure, and death. Adrenergic receptors play a key role in regu