Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Zuleyha Ozen"'
Autor:
Radha Charan Dash, Kaitlyn R. McCarthy, M. Kyle Hadden, Cynthia A. Harris, Dmitry M. Korzhnev, Alessandro A. Rizzo, Nimrat Chatterjee, Zuleyha Ozen, Graham C. Walker
Publikováno v:
ChemMedChem
PMC
PMC
© 2019 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim Translesion synthesis (TLS) has emerged as a mechanism through which several forms of cancer develop acquired resistance to first-line genotoxic chemotherapies by allowing replication to continue in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f00fb8fd4c063f54cfdde986091c67e
https://doi.org/10.1002/cmdc.201900307
https://doi.org/10.1002/cmdc.201900307
Autor:
Socheata Lim, Dmitry M. Korzhnev, Zuleyha Ozen, Alessandro A. Rizzo, M. Kyle Hadden, Radha Charan Dash
Publikováno v:
Journal of chemical information and modeling. 58(11)
Translesion synthesis (TLS) is a mechanism of replication past damaged DNA through which multiple forms of human cancer survive and acquire resistance to first-line genotoxic chemotherapies. As such, TLS is emerging as a promising target for the deve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::094e1a12a17657a3961cb49736d7cb07
https://pubmed.ncbi.nlm.nih.gov/30289707
https://pubmed.ncbi.nlm.nih.gov/30289707
Autor:
Zuleyha Ozen, M. Kyle Hadden, Samantha A Chow, Radha Charan Dash, Alessandro A. Rizzo, Kaitlyn R. McCarthy, Dmitry M. Korzhnev
Publikováno v:
Bioorganicmedicinal chemistry. 26(14)
Translesion synthesis (TLS) is a DNA damage tolerance mechanism that allows replicative bypass of DNA lesions, including DNA adducts formed by cancer chemotherapeutics. Previous studies demonstrated that suppression of TLS can increase sensitivity of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e79401ca23c4c86f5af2f73c34803933
https://pubmed.ncbi.nlm.nih.gov/30037752
https://pubmed.ncbi.nlm.nih.gov/30037752
Autor:
Vibhavari Sail, Alessandro A. Rizzo, Dmitry M. Korzhnev, Radha Charan Dash, Nimrat Chatterjee, Zuleyha Ozen, Graham C. Walker, M. Kyle Hadden
Translesion synthesis (TLS) is an important mechanism through which proliferating cells tolerate DNA damage during replication. The mutagenic Rev1/Polζ-dependent branch of TLS helps cancer cells survive first-line genotoxic chemotherapy and introduc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad5bbe7847df8b2ecef2af1702469169
https://europepmc.org/articles/PMC5992617/
https://europepmc.org/articles/PMC5992617/
