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Genetic determinants of blood pressure and heart rate identified through ENU-induced mutagenesis with automated meiotic mapping.

Autor: Teixeira SK; Laboratório de Genética e Cardiologia Molecular, Instituto do Coração, Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil., Pontes R; Laboratório de Genética e Cardiologia Molecular, Instituto do Coração, Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil., Zuleta LFG; Laboratório de Genética e Cardiologia Molecular, Instituto do Coração, Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil., Wang J; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX, USA., Xu D; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX, USA., Hildebrand S; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX, USA., Russell J; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX, USA., Zhan X; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX, USA., Choi M; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX, USA., Tang M; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX, USA., Li X; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX, USA., Ludwig S; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX, USA., Beutler B; Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX, USA., Krieger JE; Laboratório de Genética e Cardiologia Molecular, Instituto do Coração, Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil.

Publikováno v: Science advances [Sci Adv] 2024 Mar; Vol. 10 (9), pp. eadj9797. Date of Electronic Publication: 2024 Mar 01.