Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Zulaikha Akbar"'
Autor:
Pedro Horna, Matthew J. Weybright, Mathieu Ferrari, Dennis Jungherz, YaYi Peng, Zulaikha Akbar, F. Tudor Ilca, Gregory E. Otteson, Jansen N. Seheult, Janosch Ortmann, Min Shi, Paul M. Maciocia, Marco Herling, Martin A. Pule, Horatiu Olteanu
Publikováno v:
Blood Cancer Journal, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract The diagnosis of leukemic T-cell malignancies is often challenging, due to overlapping features with reactive T-cells and limitations of currently available T-cell clonality assays. Recently developed therapeutic antibodies specific for the
Externí odkaz:
https://doaj.org/article/48857f99de054473875e959f04e0679a
Autor:
Mathieu Ferrari, Matteo Righi, Vania Baldan, Patrycja Wawrzyniecka, Anna Bulek, Alexander Kinna, Biao Ma, Reyisa Bughda, Zulaikha Akbar, Saket Srivastava, Isaac Gannon, Mathew Robson, James Sillibourne, Ram Jha, Mohamed El-Kholy, Oliver Muhammad Amin, Evangelia Kokalaki, Mohammed Amin Banani, Rehan Hussain, William Day, Wen Chean Lim, Priyanka Ghongane, Jade R. Hopkins, Dennis Jungherz, Marco Herling, Martin Welin, Sachin Surade, Michael Dyson, John McCafferty, Derek Logan, Shaun Cordoba, Simon Thomas, Andrew Sewell, Paul Maciocia, Shimobi Onuoha, Martin Pule
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Peripheral T cell lymphomas are typically aggressive with a poor prognosis. Unlike other hematologic malignancies, the lack of target antigens to discriminate healthy from malignant cells limits the efficacy of immunotherapeutic approaches.
Externí odkaz:
https://doaj.org/article/0a0cba1c19b24f4e8e75069f7a2b0924
Autor:
Simon Thomas, Julia Taylor, Manuel Rodriguez-Justo, Kwee Yong, Mathieu Ferrari, Shimobi Onuoha, Sonja Zweegman, Rakesh Popat, Lydia Lee, Wen Chean Lim, Daria Galas-Filipowicz, Kent Fung, Dominic Patel, Zulaikha Akbar, Elena Alvarez Mediavilla, Patrycja Wawrzyniecka, Debarati Shome, Rogier M Reijmers, Trillian Gregg, Leigh Wood, William Day, Virginie Cerec, Shaun Cordoba, Nushmia Khokhar, Vijay Peddareddigari, Muhammad Al-Hajj, Jim Cavet, Martin Pule
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 6 (2023)
Background We used a proliferating ligand (APRIL) to construct a ligand-based third generation chimeric antigen receptor (CAR) able to target two myeloma antigens, B-cell maturation antigen (BCMA) and transmembrane activator and CAML interactor.Metho
Externí odkaz:
https://doaj.org/article/8067650d1c374058a81e8dfb09c80620
Autor:
Leila Mekkaoui, Emma Bentley, Mathieu Ferrari, Katarina Lamb, Katarzyna Ward, Rajeev Karattil, Zulaikha Akbar, Reyisa Bughda, James Sillibourne, Shimobi Onuoha, Giada Mattiuzzo, Yasu Takeuchi, Martin Pule
Publikováno v:
Bio-Protocol, Vol 11, Iss 16 (2021)
The use of recombinant lentivirus pseudotyped with the coronavirus Spike protein of SARS-CoV-2 would circumvent the requirement of biosafety-level 3 (BSL-3) containment facilities for the handling of SARS-CoV-2 viruses. Herein, we describe a fast and
Externí odkaz:
https://doaj.org/article/562d7684ec5d4b66a9d08a16484d69e1
Autor:
Mathieu Ferrari, Vania Baldan, Patrycja Wawrzyniecka, Anna Bulek, Alex Kinna, Biao Ma, Reyisa Bugda, Zulaikha Akbar, Saket Srivast, Priyankha Ghongane, Isaac Gannon, Matthew Robson, James Sillibourne, Ram Jha, Wen Chean Lim, Jade Hopkins, Martin Welin, Sachin Surade, Michael Dyson, John McCafferty, Shaun Cordoba, Simon Thomas, Derek Logan, Andy Sewell, Paul Maciocia, Shimobi Onuoha, Martin Pule
Peripheral T cell lymphomas are typically aggressive with a poor prognosis. Unlike other hematologic malignancies, the lack of target antigens to discriminate healthy from malignant cells has limited the efficacy of immunotherapeutic approaches. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1bb26831952ccaeec228571bdbf82da9
https://doi.org/10.21203/rs.3.rs-1475171/v1
https://doi.org/10.21203/rs.3.rs-1475171/v1
Autor:
Alexander Kinna, Rajeev Karattil, Zulaikha Akbar, Giada Mattiuzzo, Vania Baldan, James Sillibourne, Mathieu Ferrari, Yasuhiro Takeuchi, Christopher D.C. Allen, Katarzyna Ward, Katarina Lamb, Martin Pule, Shimobi Onuoha, Reyisa Bughda, Leila Mekkaoui, Emma M. Bentley, Philip Wu, F. Tudor Ilca, Farhaan Parekh, Preeta Datta
Publikováno v:
Journal of Virology
The human angiotensin-converting enzyme 2 acts as the host cell receptor for SARS-CoV-2 and the other members of the Coronaviridae family SARS-CoV-1 and HCoV-NL63. Here, we report the biophysical properties of the SARS-CoV-2 spike variants D614G, B.1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c04af08f3b7537dc264e8a926d82d11
https://doi.org/10.1128/jvi.00685-21
https://doi.org/10.1128/jvi.00685-21
Autor:
Zulaikha Akbar, Ami Miller, Terence H. Rabbitts, Giada Mattiuzzo, Mathieu Ferrari, F. Tudor Ilca, Adam Leach, Shimobi Onuoha, Hanif Ali, Emma M. Bentley
Publikováno v:
Antiviral Research
The SARS-CoV-2 receptor angiotensin converting enzyme 2 (ACE2) was previously engineered into a high affinity tetravalent format (ACE2-Fc-TD) that is a potential decoy protein in SARS-CoV-2 infection.We report that this protein shows greatly enhanced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb4f7199430b11ab8fc5135b4b07e6b4
https://pubmed.ncbi.nlm.nih.gov/34375715
https://pubmed.ncbi.nlm.nih.gov/34375715
Autor:
Giada Mattiuzzo, Shimobi Onuoha, Zulaikha Akbar, Rajeev Karattil, Katarzyna Ward, Katarina Lamb, Mathieu Ferrari, Yasuhiro Takeuchi, Martin Pule, Reyisa Bughda, Leila Mekkaoui, James Sillibourne, Emma M. Bentley
Publikováno v:
Bio Protoc
The use of recombinant lentivirus pseudotyped with the coronavirus Spike protein of SARS-CoV-2 would circumvent the requirement of biosafety-level 3 (BSL-3) containment facilities for the handling of SARS-CoV-2 viruses. Herein, we describe a fast and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20bc25e6260407441d8c5c8e7a169c9f
https://doi.org/10.21769/bioprotoc.4194
https://doi.org/10.21769/bioprotoc.4194
Autor:
Patrycja Wawrzyniecka, Paul Maciocia, Alex Nicholson, Shimobi Onuoha, Martin Pule, Reyisa Bughda, Mathieu Ferrari, Zulaikha Akbar, Priyanka Ghongane, Shaun Cordoba, Simon Thomas, Vania Baldan
Publikováno v:
Cancer Research. 80:2183-2183
Background: Mature T cell lymphomas are aggressive, treatment resistant cancers that are associated with poor prognosis. Clinical application of immunotherapeutic approaches has been limited by a lack of target antigens that discriminate malignant fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b8db6ca50afea64186bec3b47163fbf
https://doi.org/10.1158/1538-7445.am2020-2183
https://doi.org/10.1158/1538-7445.am2020-2183