Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Zuhair I. Abdulla"'
Publikováno v:
Pharmacological Research, Vol 191, Iss , Pp 106745- (2023)
Human epidemiological studies have identified links between nicotine intake and stress disorders, including anxiety, depression and PTSD. Here we review the clinical evidence for activation and desensitization of nicotinic acetylcholine receptors (nA
Externí odkaz:
https://doaj.org/article/445ddf87ca26496686d98dfc121af820
Autor:
Nicholas Delcimmuto, Matthew R. Skelton, Kenea C. Udobi, Zuhair I. Abdulla, Amanda N. Kokenge, Marla K. Perna
Publikováno v:
J Inherit Metab Dis
Creatine (Cr) is a guanidino compound that provides readily-available phosphate pools for the regeneration of spent ATP. The lack of brain Cr causes moderate to severe intellectual disability, language impairment, and epilepsy. The most prevalent cau
Autor:
Nina A. Atanasova, Matthew R. Skelton, Laurie L. Davenport, Michael T. Williams, Zuhair I. Abdulla, Charles V. Vorhees, Robyn M. Amos-Kroohs
Publikováno v:
Neurotoxicology and Teratology. 59:16-26
Manganese (Mn) is an essential element but neurotoxic at higher exposure levels. The effects of Mn overexposure (MnOE) on hippocampal and striatal-dependent learning and memory in rats were tested in combination with iron deficiency (FeD) and develop
Autor:
Sean P. Colgan, Matthew R. Skelton, Louis E. Glover, Mark E. Gerich, Emily M. Murphy, Rachael Dran, Zuhair I. Abdulla, J. Scott Lee, Caroline H. T. Hall
Publikováno v:
Gastroenterology
Background & Aims Patients with inflammatory bowel diseases (IBDs) have intestinal barrier dysfunction. Creatine regulates energy distribution within cells and reduces the severity of colitis in mice. We studied the functions of the creatine transpor
Deletion of the Creatine Transporter (Slc6a8) in Dopaminergic Neurons Leads to Hyperactivity in Mice
Autor:
Kim B. Seroogy, Matthew R. Skelton, Kenea C. Udobi, Kerstin H. Lundgren, Bahar Pahlevani, Zuhair I. Abdulla, Jordan L. Pennington
Publikováno v:
J Mol Neurosci
The lack of cerebral creatine (Cr) causes intellectual disability and epilepsy. In addition, a significant portion of individuals with Cr transporter (Crt) deficiency (CTD), the leading cause of cerebral Cr deficiency syndromes (CCDS), are diagnosed
Approximately 20% of adults in the U.S. will experience an affective disorder during their life. While it is well established that serotonin (5-HT) is a crucial factor in mood, impaired cellular bioenergetics are also implicated. Creatine (Cr), throu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a77baed6e0483ef17ba7eff389a3149c
Autor:
Nikita Latushka, Zuhair I. Abdulla, Bahar Pahlevani, Matthew R. Skelton, Jordan L. Pennington
Creatine (Cr) is required for proper neuronal function, as evidenced by the intellectual disability and epileptic phenotype seen in patients with cerebral Cr deficiency syndromes (CCDS). In addition, attention-deficit hyperactivity disorder (ADHD) is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9a094fea35e3ab33551de066e45ce50
Autor:
Ryan J. Lee, Zuhair I. Abdulla, Graham J. Kaplan, Sanders A. McDougall, Alena Mohd-Yusof, Cynthia A. Crawford
Publikováno v:
European journal of pharmacology. 706(1-3)
Administering manganese chloride (Mn) to rats on postnatal day (PD) 1-21 causes long-term reductions in dopamine transporter levels in the dorsal striatum, as well as a persistent increase in D1 and D2 receptor concentrations. Whether dopamine autore