The Antimicrobial Properties of Pd ^II - and Ru ^II -pyta Complexes.

Autor: van Niekerk A; Department of Chemistry and Polymer Science, University of Stellenbosch, Stellenbosch, Private bag X1, Matieland, 7602, South Africa., Joseph MC; Molecular Science Institute, School of Chemistry, University of the Witwatersrand, Johannesburg, PO Wits, 2050, South Africa., Kavanagh A; Centre for Superbug Solutions Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland, 4072, Australia., Dinh H; School of Natural Sciences ARC Centre of Excellence in Synthetic Biology, Macquarie University, Sydney, NSW, 2109, Australia., Swarts AJ; Molecular Science Institute, School of Chemistry, University of the Witwatersrand, Johannesburg, PO Wits, 2050, South Africa., Mapolie SF; Department of Chemistry and Polymer Science, University of Stellenbosch, Stellenbosch, Private bag X1, Matieland, 7602, South Africa., Zuegg J; Centre for Superbug Solutions Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland, 4072, Australia., Cain AK; School of Natural Sciences ARC Centre of Excellence in Synthetic Biology, Macquarie University, Sydney, NSW, 2109, Australia., Elliott AG; Centre for Superbug Solutions Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland, 4072, Australia., Blaskovich MAT; Centre for Superbug Solutions Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland, 4072, Australia., Frei A; Dept. of Chemistry, Biochemistry & Pharmaceutical Sciences, University of Bern, Freiestrasse 3, 3012, Bern, Switzerland.

Publikováno v: Chembiochem : a European journal of chemical biology [Chembiochem] 2023 Oct 04; Vol. 24 (19), pp. e202300247. Date of Electronic Publication: 2023 Sep 05.

Discovery of Cephalosporin-3'-Diazeniumdiolates That Show Dual Antibacterial and Antibiofilm Effects against Pseudomonas aeruginosa Clinical Cystic Fibrosis Isolates and Efficacy in a Murine Respiratory Infection Model

Autor: Rineh, A, Soren, O, McEwan, T, Ravikumar, V, Poh, WH, Azamifar, F, Naimi-Jamal, MR, Cheung, C-Y, Elliott, AG, Zuegg, J, Blaskovich, MAT, Cooper, MA, Dolange, V, Christodoulides, M, Cook, GM, Rice, SA, Faust, SN, Webb, JS, Kelso, MJ

The formation of biofilms provides a formidable defense for many bacteria against antibiotics and host immune responses. As a consequence, biofilms are thought to be the root cause of most chronic infections, including those occurring on medical indw

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______363::ba29ba7d6bf0df2788f19125d1e58314
https://hdl.handle.net/10453/142262

A Subset Screen of the Compounds Australia Scaffold Library Identifies 7-Acylaminodibenzoxazepinones as Potent and Selective Hits for Anti- Giardia Drug Discovery.

Autor: Hart CJS; Department of Microbiology and Molecular Genetics, University of California Davis, Davis, CA 95616, USA., Riches AG; Commonwealth Scientific and Industrial Research Organization, Biomedical Manufacturing, Clayton, VIC 3168, Australia., Tiash S; Griffith Institute for Drug Discovery, Griffith University, Nathan, QLD 4111, Australia., Clapper E; Griffith Institute for Drug Discovery, Griffith University, Nathan, QLD 4111, Australia., Ramu S; Institute for Molecular Bioscience, The University of Queensland, St Lucia, QLD 4072, Australia., Zuegg J; Institute for Molecular Bioscience, The University of Queensland, St Lucia, QLD 4072, Australia., Ryan JH; Commonwealth Scientific and Industrial Research Organization, Biomedical Manufacturing, Clayton, VIC 3168, Australia., Skinner-Adams TS; Griffith Institute for Drug Discovery, Griffith University, Nathan, QLD 4111, Australia.

Publikováno v: Biomedicines [Biomedicines] 2022 Dec 08; Vol. 10 (12). Date of Electronic Publication: 2022 Dec 08.

A lipoglycopeptide antibiotic for Gram-positive biofilm-related infections.

Autor: Blaskovich MAT; Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia., Hansford KA; Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia., Butler MS; Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia., Ramu S; Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia., Kavanagh AM; Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia., Jarrad AM; Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia., Prasetyoputri A; Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia., Pitt ME; Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia., Huang JX; Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia., Lindahl F; Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia., Ziora ZM; Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia., Bradford T; Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia., Muldoon C; Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia., Rajaratnam P; Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia., Pelingon R; Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia., Edwards DJ; Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia., Zhang B; Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia., Amado M; Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia., Elliott AG; Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia., Zuegg J; Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia., Coin L; Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia., Woischnig AK; University and University Hospital of Basel, Division of Infectious Diseases and Infection Biology Laboratory Department of Biomedicine, Hebelstrasse 20, CH-4031 Basel, Switzerland., Khanna N; University and University Hospital of Basel, Division of Infectious Diseases and Infection Biology Laboratory Department of Biomedicine, Hebelstrasse 20, CH-4031 Basel, Switzerland., Breidenstein E; Summit Therapeutics, The Works, Unity Campus, Cambridgeshire, CB22 3FT, UK., Stincone A; Summit Therapeutics, The Works, Unity Campus, Cambridgeshire, CB22 3FT, UK., Mason C; Summit Therapeutics, The Works, Unity Campus, Cambridgeshire, CB22 3FT, UK., Khan N; Summit Therapeutics, The Works, Unity Campus, Cambridgeshire, CB22 3FT, UK., Cho HK; Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA., Karau MJ; Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA., Greenwood-Quaintance KE; Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA., Patel R; Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA.; Division of Public Health, Infectious Diseases and Occupational Medicine, Department of Medicine, Mayo Clinic, Rochester, MN 55905, USA., Wootton M; Specialist Antimicrobial Chemotherapy Unit Public Health Wales, University Hospital of Wales, Heath Park, Cardiff CF14 4XW, Wales., James ML; Infection and Immunity Program, Monash Biomedicine Discovery Institute and Department of Microbiology, Monash University, Clayton, Victoria 3800, Australia., Hutton ML; Infection and Immunity Program, Monash Biomedicine Discovery Institute and Department of Microbiology, Monash University, Clayton, Victoria 3800, Australia., Lyras D; Infection and Immunity Program, Monash Biomedicine Discovery Institute and Department of Microbiology, Monash University, Clayton, Victoria 3800, Australia., Ogunniyi AD; Australian Centre for Antimicrobial Resistance Ecology, School of Animal and Veterinary Sciences, The University of Adelaide, Roseworthy, South Australia 5371, Australia., Mahdi LK; Australian Centre for Antimicrobial Resistance Ecology, School of Animal and Veterinary Sciences, The University of Adelaide, Roseworthy, South Australia 5371, Australia., Trott DJ; Australian Centre for Antimicrobial Resistance Ecology, School of Animal and Veterinary Sciences, The University of Adelaide, Roseworthy, South Australia 5371, Australia., Wu X; Antimicrobial Discovery Center, Department of Biology, Northeastern University, 360 Huntington Avenue, Boston, MA 02115, USA., Niles S; Antimicrobial Discovery Center, Department of Biology, Northeastern University, 360 Huntington Avenue, Boston, MA 02115, USA., Lewis K; Antimicrobial Discovery Center, Department of Biology, Northeastern University, 360 Huntington Avenue, Boston, MA 02115, USA., Smith JR; Anti-Infective Research Laboratory, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI 48201, USA., Barber KE; Anti-Infective Research Laboratory, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI 48201, USA., Yim J; Anti-Infective Research Laboratory, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI 48201, USA., Rice SA; Anti-Infective Research Laboratory, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI 48201, USA., Rybak MJ; Anti-Infective Research Laboratory, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI 48201, USA.; School of Medicine, Wayne State University, Detroit, MI 48201, USA., Ishmael CR; Department of Orthopaedic Surgery, University of California, Los Angeles (UCLA), Los Angeles, CA 90095, USA., Hori KR; Department of Orthopaedic Surgery, University of California, Los Angeles (UCLA), Los Angeles, CA 90095, USA., Bernthal NM; Department of Orthopaedic Surgery, University of California, Los Angeles (UCLA), Los Angeles, CA 90095, USA., Francis KP; Department of Orthopaedic Surgery, University of California, Los Angeles (UCLA), Los Angeles, CA 90095, USA.; PerkinElmer, 68 Elm Street, Hopkinton, MA 01748, USA., Roberts JA; University of Queensland Centre for Clinical Research, Faculty of Medicine, The University of Queensland, Brisbane, Queensland 4029, Australia.; Departments of Pharmacy and Intensive Care Medicine, Royal Brisbane and Women's Hospital, Brisbane, Queensland 4029, Australia.; Division of Anaesthesiology Critical Care Emergency and Pain Medicine, Nîmes University Hospital, University of Montpellier, 30029 Nîmes, France., Paterson DL; University of Queensland Centre for Clinical Research, Faculty of Medicine, The University of Queensland, Brisbane, Queensland 4029, Australia., Cooper MA; Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Queensland 4072, Australia.

Publikováno v: Science translational medicine [Sci Transl Med] 2022 Sep 14; Vol. 14 (662), pp. eabj2381. Date of Electronic Publication: 2022 Sep 14.

Amino Alcohols as Potential Antibiotic and Antifungal Leads.

Autor: Baker JR; Chemistry, School of Environmental & Life Sciences, The University of Newcastle, University Drive Callaghan, Newcastle, NSW 2308, Australia., Cossar PJ; Chemistry, School of Environmental & Life Sciences, The University of Newcastle, University Drive Callaghan, Newcastle, NSW 2308, Australia., Blaskovich MAT; Community for Open Antimicrobial Drug Discovery, Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia., Elliott AG; Community for Open Antimicrobial Drug Discovery, Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia., Zuegg J; Community for Open Antimicrobial Drug Discovery, Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia., Cooper MA; Community for Open Antimicrobial Drug Discovery, Centre for Superbug Solutions, Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia., Lewis PJ; Biology, School of Environmental & Life Sciences, The University of Newcastle, University Drive Callaghan, Newcastle, NSW 2308, Australia.; Molecular Horizons, School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW 2522, Australia., McCluskey A; Chemistry, School of Environmental & Life Sciences, The University of Newcastle, University Drive Callaghan, Newcastle, NSW 2308, Australia.

Publikováno v: Molecules (Basel, Switzerland) [Molecules] 2022 Mar 22; Vol. 27 (7). Date of Electronic Publication: 2022 Mar 22.