Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Zuberwasim Sayyad"'
Publikováno v:
Viruses, Vol 16, Iss 11, p 1738 (2024)
Herpesviruses are ubiquitous DNA viruses that can establish latency and cause a range of mild to life-threatening diseases in humans. Upon infection, herpesviruses trigger the activation of several host antiviral defense programs that play critical r
Externí odkaz:
https://doaj.org/article/b1d8076376f54db7a7a26bb665ef9b3b
Autor:
Mohammad Afsar, GuanQun Liu, Lijia Jia, Eliza A. Ruben, Digant Nayak, Zuberwasim Sayyad, Priscila dos Santos Bury, Kristin E. Cano, Anindita Nayak, Xiang Ru Zhao, Ankita Shukla, Patrick Sung, Elizabeth V. Wasmuth, Michaela U. Gack, Shaun K. Olsen
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract ISG15 plays a crucial role in the innate immune response and has been well-studied due to its antiviral activity and regulation of signal transduction, apoptosis, and autophagy. ISG15 is a ubiquitin-like protein that is activated by an E1 en
Externí odkaz:
https://doaj.org/article/6fb3d47e396d433991865fc8007dfe89
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract A photoreceptor cell line, 661W, derived from a mouse retinal tumor that expresses several markers of cone photoreceptor cells has been described earlier. However, these cells can be differentiated into neuronal cells. Here, we report that t
Externí odkaz:
https://doaj.org/article/72730e92429a43929b5a51022c8d1c75
Autor:
Ghanshyam Swarup, Zuberwasim Sayyad
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Optineurin (OPTN) is an adaptor protein that is involved in mediating a variety of cellular processes such as signaling, vesicle trafficking, and autophagy. Certain mutations in OPTN (gene OPTN) are associated with primary open angle glaucoma, a lead
Externí odkaz:
https://doaj.org/article/f90304d485e54593be198fcd6a95b46e
Autor:
Zuberwasim Sayyad, Sreeram Kaveti, Debanjan Bhattacharjee, Dhiviya Vedagiri, Nishant Jain, Ghanshyam Swarup
Publikováno v:
The FEBS Journal.
Publikováno v:
The FEBS journalReferences. 288(15)
Mutations in OPTN are associated with glaucoma, an eye disease, and also with amyotrophic lateral sclerosis (ALS), a motor neuron disease. A 2-bp insertion in OPTN (691_692insAG or 2bpIns-OPTN) is associated with both glaucoma and ALS. This mutation
Autor:
Milind N. Naik, Sushma Vishwakarma, Ghanshyam Swarup, Inderjeet Kaur, Zuberwasim Sayyad, Vegesna Radha, Tarjani Vivek Dave
Publikováno v:
Neurochemistry international. 148
Studies carried out on the pathogenesis of glaucoma using murine cell lines and animal models require to be validated in human cells. Therefore, we explored the possibility of using human primary retinal cells (hPRCs) in culture as a model for molecu
Autor:
Zuberwasim Sayyad, Ghanshyam Swarup
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Frontiers in Immunology
Frontiers in Immunology
Optineurin (OPTN) is an adaptor protein that is involved in mediating a variety of cellular processes such as signaling, vesicle trafficking, and autophagy. Certain mutations in OPTN (gene OPTN) are associated with primary open angle glaucoma, a lead
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Scientific Reports
Scientific Reports
A photoreceptor cell line, 661W, derived from a mouse retinal tumor that expresses several markers of cone photoreceptor cells has been described earlier. However, these cells can be differentiated into neuronal cells. Here, we report that this cell
Autor:
Akruti Yatendra Shah, Renu Sudhakar, Rajesh Prasad, Atul, Rahul Navale, Puran Singh Sijwali, Venkata Karunakar Kolla, Neha Singhal, Zuberwasim Sayyad, Mandar V. Deshmukh, Aparna Devi Allanki, Nandita Tanneru, Vijayalakshmi Venkatesan
Publikováno v:
Molecular and biochemical parasitology. 202(2)
Falcipain-3 (FP3) is an essential and drug target cysteine protease of the most lethal human malaria parasite Plasmodium falciparum. FP3 and its majority of homologs in malaria parasites prefer Leu at the P2 position in substrates and inhibitors, whe