PPP3CB overexpression mediates EGFR TKI resistance in lung tumors via calcineurin/MEK/ERK signaling.

Autor: Gazzeri S; University Grenoble Alpes, Inserm U1209, CNRS UMR 5309, Team RNA Splicing, Cell Signaling and Response to Therapy, Institute for Advanced Biosciences, Grenoble, France sylvie.gazzeri@univ-grenoble-alpes.fr., Zubchuk N; University Grenoble Alpes, Inserm U1209, CNRS UMR 5309, Team RNA Splicing, Cell Signaling and Response to Therapy, Institute for Advanced Biosciences, Grenoble, France., Montaudon E; Laboratory of Preclinical Investigation, Translational Research Department, Institut Curie, PSL Research University, Paris, France., Nemati F; Laboratory of Preclinical Investigation, Translational Research Department, Institut Curie, PSL Research University, Paris, France., Huot-Marchand S; University Grenoble Alpes, Inserm U1209, CNRS UMR 5309, Team RNA Splicing, Cell Signaling and Response to Therapy, Institute for Advanced Biosciences, Grenoble, France., Berardi G; Department of Pneumology and Physiology, Grenoble-Alpes University Hospital, Grenoble, France., Pucciarelli A; University Grenoble Alpes, Inserm U1209, CNRS UMR 5309, Team RNA Splicing, Cell Signaling and Response to Therapy, Institute for Advanced Biosciences, Grenoble, France., Dib Y; University Grenoble Alpes, Inserm U1209, CNRS UMR 5309, Team RNA Splicing, Cell Signaling and Response to Therapy, Institute for Advanced Biosciences, Grenoble, France., Nerini D; University Grenoble Alpes, Inserm U1209, CNRS UMR 5309, Team RNA Splicing, Cell Signaling and Response to Therapy, Institute for Advanced Biosciences, Grenoble, France., Oddou C; University Grenoble Alpes, Inserm U1209, CNRS UMR 5309, Team Epigenetics, Immunity, Metabolism, Cell Signaling and Cancer, Institute for Advanced Biosciences, Grenoble, France., Pezet M; University Grenoble Alpes, Inserm U1209, CNRS UMR 5309, Platform MicroCell, Institute for Advanced Biosciences, Grenoble, France., David-Boudet L; Department of Cytology and Pathology, Grenoble-Alpes University Hospital, Grenoble, France., Ardin C; University Grenoble Alpes, Inserm U1209, CNRS UMR 5309, Team RNA Splicing, Cell Signaling and Response to Therapy, Institute for Advanced Biosciences, Grenoble, France.; Department of Pneumology and Physiology, Grenoble-Alpes University Hospital, Grenoble, France., de Fraipont F; University Grenoble Alpes, Inserm U1209, CNRS UMR 5309, Team RNA Splicing, Cell Signaling and Response to Therapy, Institute for Advanced Biosciences, Grenoble, France.; Medical Unit of Molecular Genetic (Hereditary Diseases and Oncology), Grenoble-Alpes University Hospital, Grenoble, France., Maraver A; Institut de Recherche en Cancérologie de Montpellier, INSERM U1194-ICM-Université de Montpellier, Montpellier, France., Girard N; Institut du Thorax Curie-Montsouris, Institut Curie, Paris, France., Decaudin D; Laboratory of Preclinical Investigation, Translational Research Department, Institut Curie, PSL Research University, Paris, France.; Department of Medical Oncology, Institut Curie, Paris, France., Toffart AC; University Grenoble Alpes, Inserm U1209, CNRS UMR 5309, Team RNA Splicing, Cell Signaling and Response to Therapy, Institute for Advanced Biosciences, Grenoble, France.; Department of Pneumology and Physiology, Grenoble-Alpes University Hospital, Grenoble, France., Eymin B; University Grenoble Alpes, Inserm U1209, CNRS UMR 5309, Team RNA Splicing, Cell Signaling and Response to Therapy, Institute for Advanced Biosciences, Grenoble, France beatrice.eymin@univ-grenoble-alpes.fr.

Publikováno v: Life science alliance [Life Sci Alliance] 2024 Oct 01; Vol. 7 (12). Date of Electronic Publication: 2024 Oct 01 (Print Publication: 2024).