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Heat shock protein B8 promotes proliferation and migration in lung adenocarcinoma A549 cells by maintaining mitochondrial function

Autor: Ling-Ling, Yu, Yuan, Wang, Zu-Ke, Xiao, Sheng-Song, Chen

Publikováno v: Molecular and cellular biochemistry. 476(1)

Heat shock protein B8 (HSPB8) impacts on tumor proliferation and migration of malignancy. However, the role of HSPB8 in lung adenocarcinoma (LUAC) remains unclear. The aim of this study, therefore, was to clarify whether HSPB8 could bring benefits to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3c5111993b5b9787a29178b6b390cb82
https://pubmed.ncbi.nlm.nih.gov/32926297

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A randomized, double-blind, multicenter Phase II study comparing the efficacy and safety of oral nemonoxacin with oral levofloxacin in the treatment of community-acquired pneumonia

Publikováno v: Journal of Microbiology, Immunology and Infection, Vol 50, Iss 6, Pp 811-820 (2017)

Background/Purpose: To compare the clinical efficacy and safety of nemonoxacin with levofloxacin in treating community-acquired pneumonia (CAP) in a Phase II clinical trial. Methods: One hundred ninety-two patients with CAP were randomized to receive

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c303595663936320d2852a9e14bf62f0
http://www.sciencedirect.com/science/article/pii/S1684118215009159

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Clinical evaluation of oral levofloxacin 500mg once-daily dosage for treatment of lower respiratory tract infections and urinary tract infections: a prospective multicenter study in China

Publikováno v: Journal of Infection and Chemotherapy. 15:301-311

Levofloxacin (LVFX), a fluoroquinolone agent, has a broad spectrum that covers Gram-positive and -negative bacteria and atypical pathogens. It demonstrates good clinical efficacy in the treatment of various infections, including lower respiratory tra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27f412d549790fc30d7e1cf5bef8344d
https://doi.org/10.1007/s10156-009-0713-9

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Population pharmacokinetics of oral levofloxacin 500 mg once-daily dosage in community-acquired lower respiratory tract infections: results of a prospective multicenter study in China

Autor: Yaoguo Shi, Bin Si, Qian-ming Xia, Zu-ke Xiao, Yingyuan Zhang, Sheng-hua Sun, Xiaojie Wu, Jian-an Huang, Jing Zhang, Jun-fang Xu, Guoying Cao, Yan-bin Liu

Publikováno v: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy. 15(5)

This study aimed to explore the pharmacokinetic features of levofloxacin (LVFX) in Chinese patients with infections and to confirm oral LVFX 500 mg once daily as an optimal treatment regimen based on pharmacokinetic-pharmacodynamic (PK-PD) analysis.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b9378e860cc832e7832e3c36d979a55
https://pubmed.ncbi.nlm.nih.gov/19856067

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[Clinical characteristic analysis of the first human case infected by influenza A (H5N1) in Jiangxi Province]

Autor: Wei, Zhang, Le-ying, Wen, Min, Lu, Yu, Xiong, Ke-jian, Qian, Ai-hua, Deng, Lu-sheng, Guo, Zu-ke, Xiao, Xin-sheng, Zhao, Shu-min, Duan, Zhi-gang, Xie, Zi-fen, Gao, Min, Li, Hong-quan, Shao, Guo-gan, Wang, Da-wei, Liu, Zhan-cheng, Gao

Publikováno v: Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases. 29(5)

To describe the clinical, laboratory and radiological presentation of a human case infected by influenza A (H5N1), and to understand its management and prognosis.The clinical and autopsy data of the first human case infected by influenza A (H5N1) in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::031119cc381b92935d75487588a0eb6c
https://pubmed.ncbi.nlm.nih.gov/16759484

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