Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Zu-Hong He"'
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
Cisplatin is widely used in clinical tumor chemotherapy but has severe ototoxic side effects, including tinnitus and hearing damage. This study aimed to determine the molecular mechanism underlying cisplatin-induced ototoxicity. In this study, we use
Externí odkaz:
https://doaj.org/article/25ef1aeadeba445c80e182de3c2c51c4
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Attenuation of noise-induced hair cell loss and noise-induced hearing loss (NIHL) by treatment with FK506 (tacrolimus), a calcineurin (CaN/PP2B) inhibitor used clinically as an immunosuppressant, has been previously reported, but the downstream mecha
Externí odkaz:
https://doaj.org/article/31874ab502974a5d8682756ff241287b
Autor:
Zu-hong He, Sheng-yu Zou, Ming Li, Fu-ling Liao, Xia Wu, Hai-ying Sun, Xue-yan Zhao, Yu-juan Hu, Dan Li, Xiao-xiang Xu, Sen Chen, Yu Sun, Ren-jie Chai, Wei-jia Kong
Publikováno v:
Redox Biology, Vol 28, Iss , Pp - (2020)
Inflammation is a self-defense response to protect individuals from infection and tissue damage, but excessive or persistent inflammation can have adverse effects on cell survival. Many individuals become especially susceptible to chronic-inflammatio
Externí odkaz:
https://doaj.org/article/1f15224064a84cb89d540b88b65905e8
Autor:
Peng-Wei Ma, Wei-Long Wang, Jia-Wei Chen, Hao Yuan, Pei-Heng Lu, Wei Gao, Xue-Rui Ding, Yu-Qiang Lun, Rui Liang, Zu-Hong He, Qian Yang, Lian-Jun Lu
Publikováno v:
Oxidative Medicine and Cellular Longevity. 2022:1-19
Hair cell death induced by excessive reactive oxygen species (ROS) has been identified as the major pathogenesis of noise-induced hearing loss (NIHL). Recent studies have demonstrated that cisplatin- and neomycin-induced ototoxicity can be alleviated
Publikováno v:
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Attenuation of noise-induced hair cell loss and noise-induced hearing loss (NIHL) by treatment with FK506 (tacrolimus), a calcineurin (CaN/PP2B) inhibitor used clinically as an immunosuppressant, has been previously reported, but the downstream mecha