Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Zu‐Cheng Shen"'
Autor:
Ting Cao, Dan Tian, Si‐Ying Wang, Yue Pan, Zhi‐Xuan Xia, Wei‐Kai Chen, Shao‐Wei Yang, Qing‐Quan Zeng, Yue‐Ling Zhao, Ling Zheng, Ning Li, Zhong‐Meng Lai, Yi‐Xiao Luo, Zu‐Cheng Shen
Publikováno v:
Advanced Science, Vol 11, Iss 46, Pp n/a-n/a (2024)
Abstract Several lines of evidence implicate that chronic periodontitis (CP) increases the risk of mental illnesses, such as anxiety and depression, yet, the associated molecular mechanism for this remains poorly defined. Here, it is reported that mi
Externí odkaz:
https://doaj.org/article/bcfa56d34f0a411a84c86ce2b5112688
Autor:
Meng-Die Li, Lu Wang, Yu-Qi Zheng, Dan-Hong Huang, Zhi-Xuan Xia, Jian-Min Liu, Dan Tian, Hui OuYang, Zi-Hao Wang, Zhen Huang, Xiao-Shan Lin, Xiao-Qian Zhu, Si-Ying Wang, Wei-Kai Chen, Shao-Wei Yang, Yue-Ling Zhao, Jia-An Liu, Zu-Cheng Shen
Publikováno v:
iScience, Vol 26, Iss 9, Pp 107561- (2023)
Summary: Palmitoyl acyltransferases (PATs) have been suggested to be involved in learning and memory. However, the underlying mechanisms have not yet been fully elucidated. Here, we found that the activity of DHHC2 was upregulated in the hippocampus
Externí odkaz:
https://doaj.org/article/b9a49af21c67450d8224e6de117c7de0
Autor:
Yu-Fei Luo, Xiao-Xia Ye, Ying-Zhao Fang, Meng-Die Li, Zhi-Xuan Xia, Jian-Min Liu, Xiao-Shan Lin, Zhen Huang, Xiao-Qian Zhu, Jun-Jie Huang, Dong-Lin Tan, Yu-Fei Zhang, Hai-Ping Liu, Jun Zhou, Zu-Cheng Shen
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Background: The mechanistic target of rapamycin complex 1 (mTORC1) signaling has served as a promising target for therapeutic intervention of major depressive disorder (MDD), but the mTORC1 signaling underlying MDD has not been well elucidated. In th
Externí odkaz:
https://doaj.org/article/3aadb14777de4859af08bac8ae503cc2
Autor:
Zu-Cheng Shen, Zhi-Xuan Xia, Jian-Min Liu, Jie-Yan Zheng, Yu-Fei Luo, Han Yang, Meng-Die Li, Ting Cao, Hai-Ping Liu, Gui-Lin Jin, Hui-Hui Huang, Chang-Xi Yu, Jun Zhou
Publikováno v:
J Neurosci
Palmitoylation may be relevant to the processes of learning and memory, and even disorders, such as post-traumatic stress disorder and aging-related cognitive decline. However, underlying mechanisms of palmitoylation in these processes remain unclear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b8e0c99fdfb10ca1197cb8343858913
https://doi.org/10.1523/jneurosci.1741-21.2022
https://doi.org/10.1523/jneurosci.1741-21.2022
Autor:
Meng-Die Li, Dan-Hong Huang, Yu-Qi Zheng, Dan Tian, Hui OuYang, Ke-Xin Song, Zhen Huang, Xiao-Shan Lin, Xiao-Qian Zhu, Jun-Jie Huang, Si-Ying Wang, Wei-Kai Chen, Shao-Wei Yang, Jian-Min Liu, Zhi-Xuan Xia, Zu-Cheng Shen
Background A-kinase anchoring protein 79/150 (AKAP150) has been suggested to be involved in learning and memory, and synaptic plasticity in the hippocampus is closely associated with memory. However, its effect and underlying mechanisms have not yet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7b3b8f30e282818167b88a7806bdde9
https://doi.org/10.21203/rs.3.rs-2180782/v1
https://doi.org/10.21203/rs.3.rs-2180782/v1
Autor:
Rong-cai Yue, Gui-Lin Jin, Li-Mian Hong, Hui-Hui Huang, Jian Yang, Yi Li, Ying Xu, Chang-Xi Yu, Zu-Cheng Shen, Yan-Ping Su, Bojun Xiong, Hai-Ping Liu
Publikováno v:
Phytomedicine : international journal of phytotherapy and phytopharmacology. 90
Background Diabetic neuropathic pain (DNP), a complication of diabetes, has serious impacts on human health. As the pathogenesis of DNP is very complex, clinical treatments for DNP is limited. Koumine (KM) is an active ingredient extracted from Gelse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9426d72333d3e38af2082768835ece28
https://pubmed.ncbi.nlm.nih.gov/34330066
https://pubmed.ncbi.nlm.nih.gov/34330066
Autor:
Huan-Huan Zhao, Fang Wang, Jin-Gang He, Hai Zhang, Jun-Feng Xu, Hui-Ling Zheng, Zhuang-Li Hu, Pei-Wei Zhang, Jian-Guo Chen, Shuang-Qi Gao, Zu-Cheng Shen
Publikováno v:
Addiction Biology. 25
Cocaine is a common abused drug that can induce abnormal synaptic and immune responses in the central nervous system (CNS). High mobility group box 1 (HMGB1) is one kind of inflammatory molecules that is expressed both on neurons and immune cells. Pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e79084ad0727a9352b06f2930fb4311
https://doi.org/10.1111/adb.12739
https://doi.org/10.1111/adb.12739
Autor:
Hui-Ling Zheng, Xia-Ping Yao, Wen-Hui Liu, Zhi-Xuan Xia, Jia-Jing Lu, Jian-Guo Chen, Li-Hong Long, Tai-Lei Nie, Peng-Fei Wu, Fang Wang, Zu-Cheng Shen, Shao-Qi Zhang, Qiao Deng, Shuang-Qi Gao, Zhuang-Li Hu
Publikováno v:
Biological psychiatry. 85(3)
Background Benzodiazepines (BZDs) have been used to treat anxiety disorders for more than five decades as the allosteric modulator of the gamma-aminobutyric acid A receptor (GABAAR). Little is known about other mechanisms of BZDs. Here, we describe h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::956e8814f2ea5da4aca31b76df36fcab
https://pubmed.ncbi.nlm.nih.gov/30454851
https://pubmed.ncbi.nlm.nih.gov/30454851
Autor:
Li-Hong Long, Zhuang-Li Hu, Lan Ni, Zu-Cheng Shen, Tao Chen, Xin-Lei Guan, Jian-Guo Chen, Dan-Fang Yu, You Jin, Peng-Fei Wu, Fang Wang
Summary Background The AMP-activated protein kinase (AMPK) is a sensor of cellular energy and nutrient status, with substantial amount of cross talk with other signaling pathways, including its phosphorylation by Akt, PKA, and GSK3β. Aims Various si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5611f16e6673d1f3e09b3a21a8d30b3
https://europepmc.org/articles/PMC6492836/
https://europepmc.org/articles/PMC6492836/
Autor:
Peng-Fei Wu, Li-Hong Long, Han Luo, Jun Zhou, Zu-Cheng Shen, Fang Wang, Qing-Guo Xie, Jian-Min Liu, Jing Rao, Jian-Guo Chen, Fengchao Jiang, Jian-Geng Huang, Xiao Liang
Summary Aims Chemical entities containing mercapto group have been increasingly attractive in the therapy of central nerve system (CNS) diseases. In the recent study, we screened a series of mercapto-tacrine derivatives with synergistic neuropharmaco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5cb8a2bee77e43ae32b6b29cd7a2e23
https://europepmc.org/articles/PMC6492856/
https://europepmc.org/articles/PMC6492856/