Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Zsuzsanna T. Varga"'
Autor:
Mirco Schmolke, Balaji Manicassamy, Lindomar Pena, Troy Sutton, Rong Hai, Zsuzsanna T Varga, Benjamin G Hale, John Steel, Daniel R Pérez, Adolfo García-Sastre
Publikováno v:
PLoS Pathogens, Vol 7, Iss 8, p e1002186 (2011)
Highly pathogenic avian influenza A viruses (HPAIV) of the H5N1 subtype occasionally transmit from birds to humans and can cause severe systemic infections in both hosts. PB1-F2 is an alternative translation product of the viral PB1 segment that was
Externí odkaz:
https://doaj.org/article/edda94016737425b9b5e70e8e7f09537
Autor:
Zsuzsanna T Varga, Irene Ramos, Rong Hai, Mirco Schmolke, Adolfo García-Sastre, Ana Fernandez-Sesma, Peter Palese
Publikováno v:
PLoS Pathogens, Vol 7, Iss 6, p e1002067 (2011)
PB1-F2 is a 90 amino acid protein that is expressed from the +1 open reading frame in the PB1 gene of some influenza A viruses and has been shown to contribute to viral pathogenicity. Notably, a serine at position 66 (66S) in PB1-F2 is known to incre
Externí odkaz:
https://doaj.org/article/f74b89840115468bb41bf23f6754bda1
Publikováno v:
Journal of Virology. 86:8359-8366
PB1-F2 is a small, 87- to 90-amino-acid-long protein encoded by the +1 alternate open reading frame of the PB1 gene of most influenza A virus strains. It has been shown to contribute to viral pathogenicity in a host- and strain-dependent manner, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a383538dd3922d94f6358660f7290d79
https://doi.org/10.1128/jvi.01122-12
https://doi.org/10.1128/jvi.01122-12
Autor:
Zsuzsanna T. Varga, Peter Palese
Publikováno v:
Virulence. 2:542-546
PB1-F2 is a 90 amino acid protein that is expressed from the +1 open reading frame in the PB1 gene of some influenza A viruses. The PB1-F2 protein has been shown to contribute to viral pathogenicity, but the molecular mechanisms for mediating virulen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f58fc60ef39e49a77253b1d9220b323
https://doi.org/10.4161/viru.2.6.17812
https://doi.org/10.4161/viru.2.6.17812
Autor:
Elizabeth Rosenzweig, Peter Palese, Zsuzsanna T. Varga, Jennifer R. Tisoncik, Gina M. Conenello, Michael G. Katze
Publikováno v:
Journal of Virology. 85:652-662
The PB1-F2 protein of influenza A virus can contribute to viral pathogenesis of influenza virus strains. Of note, an N66S amino acid mutation in PB1-F2 has been shown to increase the pathogenesis associated with H5N1 Hong Kong/1997 and H1N1 Brevig Mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54073b282661f13e4983b548a7e76f86
https://doi.org/10.1128/jvi.01987-10
https://doi.org/10.1128/jvi.01987-10
Autor:
Balaji Manicassamy, Jessica A. Belser, Rong Hai, Terrence M. Tumpey, Zsuzsanna T. Varga, Taia T. Wang, Adolfo García-Sastre, Peter Palese, Melissa B. Pearce, Mirco Schmolke
Publikováno v:
Journal of Virology, Vol. 84, No 9 (2010) pp. 4442-50
Unlike previous pandemic viruses, the 2009 H1N1 pandemic influenza virus does not code for the virulence factor PB1-F2. The genome of the 2009 H1N1 virus contains three stop codons preventing PB1-F2 expression; however, PB1-F2 production could occur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04a5963a9adb87d985255bc9194a2feb
https://europepmc.org/articles/PMC2863736/
https://europepmc.org/articles/PMC2863736/
