Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Zsuzsanna Schelz"'
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 7, Pp 6566-6579 (2024)
Cervical cancer presents a significant challenge to the global health of women. Despite substantial advances in human papillomavirus (HPV)-related cervical cancer vaccines, non-HPV-related cervical cancer is still waiting novel therapeutic options. D
Externí odkaz:
https://doaj.org/article/c2806ffeb76142258c598715ff3bb3ae
Autor:
Nikoletta Szemerédi, Zsuzsanna Schelz, Dária Antónia Horvath, Bálint Rácz, András G. Szatmári, Hiba F. Muddather, Noémi Bózsity, István Zupkó, Gabriella Spengler
Publikováno v:
Pharmaceutics, Vol 16, Iss 7, p 877 (2024)
Chemotherapy is a known treatment modality that improves the long-term survival of breast cancer patients. However, due to the resistance to numerous anticancer drugs, alternative chemotherapeutic strategies are required. Regarding antimetabolic drug
Externí odkaz:
https://doaj.org/article/9e6f2b925ffb49268430c49ee94d86f3
Autor:
António Dembo, Etelka Ferenczi, Tamás Jernei, Andrea Bor, Zsuzsanna Schelz, István Zupkó, Szilárd Varga, Antal Csámpai
Publikováno v:
Molecules, Vol 29, Iss 2, p 375 (2024)
A series of novel triazole-tethered ferrocenoylamino-substituted cinchona–chalcone hybrids along with two representative benzoylamino-substituted reference compounds were prepared by three methods of CuAAC chemistry. In line with the limited succes
Externí odkaz:
https://doaj.org/article/10ff746eff4548a8ba892fa034f7831b
Publikováno v:
Molecules, Vol 28, Iss 24, p 7962 (2023)
A series of novel diterpene-type 1,3-aminoalcohols and their regioisomers have been synthesised from natural stevioside in a stereoselective manner. The key intermediate β-keto alcohol was prepared using Wagner–Meerwein rearrangement of the epoxid
Externí odkaz:
https://doaj.org/article/6a78e1330c9a4d4f8da727b2d2e509f3
Autor:
Jean Guillon, Marc Le Borgne, Vittoria Milano, Aurore Guédin-Beaurepaire, Stéphane Moreau, Noël Pinaud, Luisa Ronga, Solène Savrimoutou, Sandra Albenque-Rubio, Mathieu Marchivie, Haouraa Kalout, Charley Walker, Louise Chevallier, Corinne Buré, Eric Largy, Valérie Gabelica, Jean-Louis Mergny, Virginie Baylot, Jacky Ferrer, Yamina Idrissi, Edith Chevret, David Cappellen, Vanessa Desplat, Zsuzsanna Schelz, István Zupkó
Publikováno v:
Pharmaceuticals, Vol 17, Iss 1, p 30 (2023)
The syntheses of novel 2,4-bis[(substituted-aminomethyl)phenyl]phenylquinazolines 12 and 2,4-bis[(substituted-aminomethyl)phenyl]phenylquinolines 13 are reported here in six steps starting from various halogeno-quinazoline-2,4-(1H,3H)-diones or subst
Externí odkaz:
https://doaj.org/article/a1792b25a47e4834a049e8058f8ad1b4
Publikováno v:
Antibiotics, Vol 12, Iss 9, p 1468 (2023)
Efflux pump (EP)-mediated multidrug resistance (MDR) seems ubiquitous in bacterial infections and neoplastic diseases. The diversity and lack of specificity of these efflux mechanisms raise a great obstacle in developing drugs that modulate efflux pu
Externí odkaz:
https://doaj.org/article/ebdaff2a8ba24d2680f32577461e09ff
Autor:
Tibor Kovács, Ildikó Lajter, Norbert Kúsz, Zsuzsanna Schelz, Noémi Bózsity-Faragó, Anikó Borbás, István Zupkó, Georg Krupitza, Richard Frisch, Judit Hohmann, Andrea Vasas, Attila Mándi
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 6, p 5841 (2023)
A new flexible germacranolide (1, lobatolide H) was isolated from the aerial parts of Neurolaena lobata. The structure elucidation was performed by classical NMR experiments and DFT NMR calculations. Altogether, 80 theoretical level combinations with
Externí odkaz:
https://doaj.org/article/5ed48aedc1494b92b2f5642bd8ce85ca
Autor:
Dorottya Bai, Zsuzsanna Schelz, Dóra Erdős, Anna K. Kis, Viktória Nagy, István Zupkó, György T. Balogh, Zsolt Szakonyi
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 2, p 1121 (2023)
A new family of diterpene-type aminotriol derivatives has been synthesised from stevioside in a stereoselective manner. The key intermediate spiro-epoxide was prepared through the methyl ester of the allilyc diol derived from steviol. The oxirane rin
Externí odkaz:
https://doaj.org/article/d8d9ebad6dc04716a5a2912180065f94
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 18, p 10366 (2022)
A series of gibberellic acid-based aminodiols was designed and synthesized from commercially available gibberellic acid. Exposure of gibberellic acid to hydrochloric acid under reflux conditions resulted in aromatization followed by rearrangement to
Externí odkaz:
https://doaj.org/article/68852f3bbac44adcbd302b36cd550187
Autor:
Tasneem Sultan Abu Ghazal, Zsuzsanna Schelz, Lívia Vidács, Nikoletta Szemerédi, Katalin Veres, Gabriella Spengler, Judit Hohmann
Publikováno v:
Plants, Vol 11, Iss 11, p 1432 (2022)
Origanum majorana L. is a widely used medicinal plant; its distilled oil and preparations are extensively utilised in the phytotherapy and food industries. The objective of this study is to evaluate the extracts and the essential oil (EO) of Origanum
Externí odkaz:
https://doaj.org/article/658a5d6cbbd24a0fba16204da6ba5593