Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Zsuzsanna K. Zsengellér"'
Autor:
Diana Pintye, Réka E. Sziva, Lauren A. Biwer, Esilida Sula Karreci, Sonako Jacas, Maxim Mastyugin, Marianna Török, Brett C. Young, Prakash Jagtap, Garry J. Southan, Iris Z. Jaffe, Zsuzsanna K. Zsengellér
Publikováno v:
Antioxidants, Vol 12, Iss 12, p 2036 (2023)
Background: Preeclampsia (PE) is a hypertensive disorder of pregnancy that is associated with substantial morbidity and mortality for the mother and fetus. Reduced nitric oxide bioavailability and oxidative stress contribute to the maternal and fetal
Externí odkaz:
https://doaj.org/article/f21fa703289f4b9398e62a8ef00663d3
Autor:
Diana Pintye, Réka E. Sziva, Maxim Mastyugin, Brett C. Young, Sonako Jacas, Marianna Török, Saira Salahuddin, Prakash Jagtap, Garry J. Southan, Zsuzsanna K. Zsengellér
Publikováno v:
Biology, Vol 12, Iss 9, p 1229 (2023)
Background: Preeclampsia (PE) is a severe, life-threatening complication during pregnancy (~5–7%), and no causative treatment is available. Early aberrant spiral artery remodeling is associated with placental stress and the release of oxygen radica
Externí odkaz:
https://doaj.org/article/6d4aee7da3784754b6504db4a144336f
Autor:
Diana Pintye, Réka Eszter Sziva, Maxim Mastyugin, Marianna Török, Sonako Jacas, Agnes Lo, Saira Salahuddin, Zsuzsanna K. Zsengellér
Publikováno v:
Antioxidants, Vol 12, Iss 8, p 1578 (2023)
Preeclampsia (PE) is a pregnancy-specific syndrome affecting 5–7% of patients. There is no effective treatment available. Early abnormal placental development is associated with oxidative stress (OS) and a release of reactive oxygen species (ROS) i
Externí odkaz:
https://doaj.org/article/303949927fb940268b508d7af93108bd
Autor:
Zsuzsanna K. Zsengellér, Agnes Lo, Mahtab Tavasoli, Elizabeth Pernicone, S. Ananth Karumanchi, Seymour Rosen
Publikováno v:
Kidney International Reports, Vol 4, Iss 12, Pp 1735-1741 (2019)
Introduction: Soluble fms-like tyrosine kinase 1 (sFLT1) is a splice variant of the vascular endothelial growth factor (VEGF) receptor lacking the transmembrane and cytoplasmic domains and acts as a powerful antagonist of VEGF signaling. Plasma sFLT1
Externí odkaz:
https://doaj.org/article/ee9bd67e9f1a45cbb54f2311ca1179a6
Autor:
Amanda J. Clark, Marie Christelle Saade, Vamsidhara Vemireddy, Kyle Q. Vu, Brenda Mendoza Flores, Valerie Etzrodt, Erin J. Ciampa, Huihui Huang, Ayumi Takakura, Kambiz Zandi-Nejad, Zsuzsanna K. Zsengellér, Samir M. Parikh
Nicotinamide adenine dinucleotide (NAD+) levels decline in experimental models of acute kidney injury (AKI). Attenuated enzymatic conversion of tryptophan to NAD+ in tubular epithelium may contribute to adverse cellular and physiological outcomes. Me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a498630bd9b4caab45b365ff79965c9
https://doi.org/10.1101/2023.05.23.541987
https://doi.org/10.1101/2023.05.23.541987
Autor:
Asumi Iesato, Carmen Priolo, Xiaowen Liu, Isaac E. Stillman, Suzanne D. Burke, Carmelo Nucera, Zsuzsanna K. Zsengellér, Alfredo Pontecorvi, Veronica Valvo, Taylor R. Kavanagh
Publikováno v:
Thyroid. 31:1335-1358
Background: BRAFV600E acts as an ATP-dependent cytosolic kinase. BRAFV600E inhibitors are widely available, but resistance to them is widely reported in the clinic. Lipid metabolism (fatty acids) i...
Autor:
Saira Salahuddin, Ambart E. Covarrubias, S. Ananth Karumanchi, Agnes Lo, Edouard Lecarpentier, Zsuzsanna K. Zsengellér, Bassam Haddad, Ravi Thadhani
Publikováno v:
Hypertension. 76:875-883
Elevated circulating sFLT-1 (soluble fms-like tyrosine kinase) and low levels of its ligand, PlGF (placental growth factor), are key characteristics of preeclampsia. However, it is unclear if the low levels of plasma PlGF noted during preeclampsia ar
Autor:
Zsuzsanna K. Zsengellér, Marianna Török, Maxim Mastyugin, Agnes Lo, Ananth Karumanchi, Béla Török, Saira Salahuddin
Publikováno v:
Hypertension. 78
Background: Preeclampsia (PE) is a pregnancy-specific syndrome affecting 5-7% of all pregnant women, and there is no effective treatment available. Early abnormal placental development is associated with oxidative stress and the release of reactive o
Autor:
Angelo Blasio, Jose M. Magraner, Shrijal S Shah, Martin R. Pollak, Balajikarthick Subramanian, Isaac E. Stillman, Olivia G Donovan, Gizelle M McCarthy, Althea Bock-Hughes, Zsuzsanna K. Zsengellér, Jung Hee Suh, Lena B Schaller, David J. Friedman, Calum F Tattersfield
Publikováno v:
Disease Models & Mechanisms
article-version (VoR) Version of Record
Disease Models & Mechanisms, Vol 14, Iss 8 (2021)
article-version (VoR) Version of Record
Disease Models & Mechanisms, Vol 14, Iss 8 (2021)
People of recent sub-Saharan African ancestry develop kidney failure much more frequently than other groups. A large fraction of this disparity is due to two coding sequence variants in the APOL1 gene. Inheriting two copies of these APOL1 risk varian
Autor:
Mahtab Tavasoli, S. Ananth Karumanchi, Agnes Lo, Zsuzsanna K. Zsengellér, Seymour Rosen, Elizabeth Pernicone
Publikováno v:
Kidney International Reports
Kidney International Reports, Vol 4, Iss 12, Pp 1735-1741 (2019)
Kidney International Reports, Vol 4, Iss 12, Pp 1735-1741 (2019)
Introduction: Soluble fms-like tyrosine kinase 1 (sFLT1) is a splice variant of the vascular endothelial growth factor (VEGF) receptor lacking the transmembrane and cytoplasmic domains and acts as a powerful antagonist of VEGF signaling. Plasma sFLT1