Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Zsuzsanna Bebok"'
Autor:
Naoe Harafuji, Chaozhe Yang, Maoqing Wu, Girija Thiruvengadam, Heather Gordish-Dressman, R. Griffin Thompson, P. Darwin Bell, Avi Z. Rosenberg, Claudia Dafinger, Max C. Liebau, Zsuzsanna Bebok, Ljubica Caldovic, Lisa M. Guay-Woodford
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Autosomal recessive polycystic kidney disease (ARPKD; MIM#263200) is a severe, hereditary, hepato-renal fibrocystic disorder that leads to early childhood morbidity and mortality. Typical forms of ARPKD are caused by pathogenic variants in the PKHD1
Externí odkaz:
https://doaj.org/article/30852107202d4088b3304c8e12f24d6b
Autor:
Do Yeon Cho, Shaoyan Zhang, Ahmed Lazrak, Daniel Skinner, Harrison M. Thompson, Jessica Grayson, Purushotham Guroji, Saurabh Aggarwal, Zsuzsanna Bebok, Steven M. Rowe, Sadis Matalon, Eric J. Sorscher, Bradford A. Woodworth
Publikováno v:
Redox Biology, Vol 43, Iss , Pp 101998- (2021)
Lipopolysaccharide (LPS) serves as the interface between gram-negative bacteria (GNB) and the innate immune response in respiratory epithelial cells (REC). Herein, we describe a novel biological role of LPS that permits GNB to persist in the respirat
Externí odkaz:
https://doaj.org/article/833ac3ac1c0742a7bd95fc923f346f51
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0155882 (2016)
The most common mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene leads to deletion of the phenylalanine at position 508 (ΔF508) in the CFTR protein and causes multiple folding and functional defects. Contrary to large-
Externí odkaz:
https://doaj.org/article/948aedcb4f444aac89e9fab9971d9f0b
Autor:
Yogesh Bhootada, Pravallika Kotla, Sergei Zolotukhin, Oleg Gorbatyuk, Zsuzsanna Bebok, Mohammad Athar, Marina Gorbatyuk
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0154779 (2016)
T17M rhodopsin expression in rod photoreceptors leads to severe retinal degeneration and is associated with the activation of ER stress related Unfolded Protein Response (UPR) signaling. Here, we show a novel role of a UPR transcription factor, ATF4,
Externí odkaz:
https://doaj.org/article/83a236745f18415f9c9945e49c49177a
Autor:
Yiming Zhang, Chaozhe Yang, Wei Wang, Naoe Harafuji, Piotr Stasiak, P. Darwin Bell, Ljuba Caldovic, Elizabeth Sztul, Lisa M. Guay-Woodford, Zsuzsanna Bebok
Autosomal recessive polycystic kidney disease (ARPKD) is caused primarily by mutations inPKHD1, encoding fibrocystin (FPC), butPkhd1mutant mice fail to express renal cystic disease. In contrast, the renal lesion inCys1cpk/cpk(cpk) mice with loss of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9cef85368055265de676337fd3599e82
https://doi.org/10.1101/2022.04.19.488799
https://doi.org/10.1101/2022.04.19.488799
Autor:
Bradford A. Woodworth, Steven M. Rowe, Zsuzsanna Bebok, Daniel Skinner, Jessica W. Grayson, Purushotham Guroji, Eric J. Sorscher, Shaoyan Zhang, Do-Yeon Cho, Ahmed Lazrak, Saurabh Aggarwal, Harrison M. Thompson, Sadis Matalon
Publikováno v:
Redox Biology
Redox Biology, Vol 43, Iss, Pp 101998-(2021)
Redox Biology, Vol 43, Iss, Pp 101998-(2021)
Lipopolysaccharide (LPS) serves as the interface between gram-negative bacteria (GNB) and the innate immune response in respiratory epithelial cells (REC). Herein, we describe a novel biological role of LPS that permits GNB to persist in the respirat
Autor:
Zsuzsanna Bebok, Ahmed Lazrak, Kevin S. Harrod, Sadis Matalon, James D. Londino, James F. Collawn
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology
The cystic fibrosis transmembrane conductance regulator (CFTR) and the amiloride-sensitive epithelial sodium channels (ENaC) are located in the apical membranes of airway and alveolar epithelial cells. These transporters play an important role in the
Publikováno v:
The FASEB Journal. 30:201-213
Synonymous mutations, such as I507-ATC→ATT, in deletion of Phe508 in cystic fibrosis transmembrane conductance regulator (ΔF508 CFTR), the most frequent disease-associated mutant of CFTR, may affect protein biogenesis, structure, and function and
Autor:
Vedrana Bali, Zsuzsanna Bebok
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 64:58-74
Synonymous codon usage has been a focus of investigation since the discovery of the genetic code and its redundancy. The occurrences of synonymous codons vary between species and within genes of the same genome, known as codon usage bias. Today, bioi
Autor:
Dale J. Benos, Niren Kapoor, Zsuzsanna Bebok, Yawar J. Qadri, James K. Bubien, Rafal Bartoszewski, Catherine M. Fuller
Publikováno v:
Journal of Biological Chemistry. 284:24526-24541
High grade gliomas such as glioblastoma multiforme express multiple members of the epithelial sodium channel (ENaC)/Degenerin family, characteristically displaying a basally active amiloride-sensitive cation current not seen in normal human astrocyte