Zobrazeno 1 - 10
of 124
pro vyhledávání: '"Zsuzsanna, Bereczky"'
Autor:
Gábor Balogh, Zsuzsanna Bereczky
Publikováno v:
Biomolecules, Vol 14, Iss 6, p 657 (2024)
Antithrombin (AT) is a critical regulator of the coagulation cascade by inhibiting multiple coagulation factors including thrombin and FXa. Binding of heparinoids to this serpin enhances the inhibition considerably. Mutations located in the heparin b
Externí odkaz:
https://doaj.org/article/4f8986548f8f4989b0e358fe2c1c042f
Autor:
Judit Kállai, Réka Gindele, Krisztina Pénzes-Daku, Gábor Balogh, Réka Bogáti, Bálint Bécsi, Éva Katona, Zsolt Oláh, Péter Ilonczai, Zoltán Boda, Ágnes Róna-Tas, László Nemes, Imelda Marton, Zsuzsanna Bereczky
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 5, p 2893 (2024)
Antithrombin (AT) is the major plasma inhibitor of thrombin (FIIa) and activated factor X (FXa), and antithrombin deficiency (ATD) is one of the most severe thrombophilic disorders. In this study, we identified nine novel AT mutations and investigate
Externí odkaz:
https://doaj.org/article/d3799ccc75994a64a076a6fd41045381
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
BackgroundThe rs867186 single-nucleotide polymorphism in the PROCR gene (g.6936A > G, c.4600A > G) results in a serine-to-glycine substitution at codon 219 of endothelial protein C receptor (EPCR). We performed a case–control study followed by an u
Externí odkaz:
https://doaj.org/article/1bc46de5d2ed4689835874f95989861e
Autor:
Shewaye Fituma Natae, Mohammed Abdulridha Merzah, János Sándor, Róza Ádány, Zsuzsanna Bereczky, Szilvia Fiatal
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
BackgroundVenous thrombosis (VT) is multifactorial trait that contributes to the global burden of cardiovascular diseases. Although abundant single nucleotide polymorphisms (SNPs) provoke the susceptibility of an individual to VT, research has found
Externí odkaz:
https://doaj.org/article/4dc1438613a147d5a5c2a8e95df77ad7
Autor:
Gábor Balogh, Zsuzsanna Bereczky
Publikováno v:
Biomolecules, Vol 13, Iss 5, p 795 (2023)
The interaction between coagulation factors Xa and IXa and the activated state of their inhibitor, antithrombin (AT),have been investigated using X-ray diffraction studies. However, only mutagenesis data are available for non-activated AT. Our aim wa
Externí odkaz:
https://doaj.org/article/f1741b5f786f41e1b58f1f8b769fa0a3
Autor:
Farzaneh Sadeghi, Sándor Kovács, Katalin Szilvia Zsóri, Zoltán Csiki, Zsuzsanna Bereczky, Amir Houshang Shemirani
Publikováno v:
Platelets, Vol 31, Iss 6, Pp 731-739 (2020)
Changes of mean platelet volume (MPV) and platelet count (PC) could be a marker or a predictor of acute stroke (AS). We conducted a systematic review and meta-analysis of the published literature on the reporting of MPV and PC in AS. Studies were inc
Externí odkaz:
https://doaj.org/article/00cc9dda52d74e21a25dc1a9b33abde1
Autor:
Shewaye Fituma Natae, Zsigmond Kósa, János Sándor, Mohammed Abdulridha Merzah, Zsuzsanna Bereczky, Péter Pikó, Róza Ádány, Szilvia Fiatal
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Background: Interactions between genetic and environmental risk factors (GxE) contribute to an increased risk of venous thromboembolism (VTE). Understanding how these factors interact provides insight for the early identification of at-risk groups wi
Externí odkaz:
https://doaj.org/article/205568638ceb42439a3c5b8424c8d334
Publikováno v:
Platelets, Vol 30, Iss 2, Pp 139-147 (2019)
The purpose of this study was to evaluate the association between platelet (PLT) count and mean platelet volume (MPV) and venous thromboembolism (VTE). Thus, this study reviewed and performed a quantitative synthesis on data from the literature. This
Externí odkaz:
https://doaj.org/article/ac36e6bee43b45a09c178d43d656b6a9
Autor:
Zsuzsanna Bereczky, Réka Gindele, Szilvia Fiatal, Marianna Speker, Tünde Miklós, László Balogh, Zoltán Mezei, Zsuzsanna Szabó, Róza Ádány
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 7 (2021)
Background: Antithrombin (AT) is one of the most important regulator of hemostasis. AT Budapest 3 (ATBp3) is a prevalent type II heparin-binding site (IIHBS) deficiency due to founder effect. Thrombosis is a complex disease including arterial (ATE) a
Externí odkaz:
https://doaj.org/article/c8503f5cc9c94c6ba830f95bc1db18bb
Autor:
Tamás Major, Csaba Csobay-Novák, Réka Gindele, Zsuzsanna Szabó, László Bora, Natália Jóni, Tamás Rácz, Tamás Karosi, Zsuzsanna Bereczky
Publikováno v:
Journal of International Medical Research, Vol 48 (2020)
Hereditary haemorrhagic telangiectasia (HHT; Osler–Weber–Rendu disease) is an autosomal dominant vascular disease characterized by nosebleeds, mucocutaneous telangiectases, visceral arteriovenous malformations (AVM) and a first-degree relative wi
Externí odkaz:
https://doaj.org/article/82f073717eab40d6a09c4c7607c71d6b