Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Zsuzsa Fabry"'
Autor:
Zsuzsa Fabry, Emily K. Reinke
Publikováno v:
Immunology Letters. 104:102-109
Immune privilege in the central nervous system (CNS) is not maintained by immune ignorance of the CNS, but by CNS control over inflammatory processes. In this review we examine the role neuropeptides play in maintenance of immune privilege in the CNS
Autor:
Brendon M. Nacewicz, Frances Liu, Zsuzsa Fabry, Sinarack Macvilay, John D. Lambris, Anna Erdei, Diane Sewell, Matyas Sandor
Publikováno v:
Journal of Neuroimmunology
The role of complement components in traumatic brain injury is poorly understood. Here we show that secondary damage after acute cryoinjury is significantly reduced in C3−/− or C5−/− mice or in mice treated with C5a receptor antagonist peptid
Autor:
Diane Sewell, Shari M. Piaskowski, Zsuzsa Fabry, Brittany Barger, Dominic B. Fee, Kelli Andresen, Thomas J Jacques, Michael N. Hart
Publikováno v:
Brain Research. 1012:52-59
Transforming growth factor beta (TGFbeta) modulates a variety of growth related functions following traumatic injury. The cellular response to TGFbeta is predominantly mediated through TGFbeta receptor I (TGFbetaRI) and receptor II (TGFbetaRII) on th
Publikováno v:
Journal of Autoimmunity. 20:125-133
Adoptive transfer of lymphocytes co-cultured with syngeneic smooth muscle (SM) cells to healthy recipient mice results in vasculitic lesions predominantly in post-capillary venules. The present study focuses on the mechanisms by which the disease-ind
Publikováno v:
Journal of Neuroimmunology. 105:169-178
The initiation step of cell-mediated immune responses in the central nervous system (CNS) involves the trafficking of the antigen-specific T cells into the brain. To study this trafficking, we developed an in vivo system for studying antigen-specific
Publikováno v:
Stroke. 44
Currently there is no treatment for the inflammatory responses that develop following cerebral ischemia. We have previously shown that the CD4+ T cell derived inflammatory cytokine IL-21 is highly upregulated in ischemic mouse brain following transie
Publikováno v:
The FASEB Journal. 22
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 26(3)
T-cell recruitment into the brain is critical in inflammatory and autoimmune diseases of the CNS. We use intracerebral antigen microinjection and tetramer technology to track antigen-specific CD8+T-cells in the CNS and to clarify the contribution of
Autor:
Bernhard O. Boehm, Harald H. Hofstetter, Zsuzsa Fabry, Alexey Y. Karulin, Juan C. Chavez, Paul V. Lehmann, Kamruz Darabi, Joseph C. LaManna, Magdalena Tary-Lehmann
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 173(1)
The initial event in the pathogenesis of autoimmune disease is thought to be the priming of naive autoreactive T cells by an infection with a cross-reactive microorganism. Although such cross-reactive priming should be a common event, autoimmune dise
Publikováno v:
Journal of neuroimmunology. 141(1-2)
Drainage and retention of brain-derived antigens are important factors in initiating and regulating immune responses in the central nervous system (CNS). We investigated distribution, immunological processing and retention of intracerebrally infused