Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Zsuzsa Bebok"'
Autor:
Sylwia Bartoszewska, Wojciech Kamysz, Bogdan Jakiela, Marek Sanak, Jarosław Króliczewski, Zsuzsa Bebok, Rafal Bartoszewski, James F. Collawn
Publikováno v:
Cellular & Molecular Biology Letters, Vol 22, Iss 1, Pp 1-14 (2017)
Abstract Background Hypoxic conditions induce the expression of hypoxia-inducible factors (HIFs) that allow cells to adapt to the changing conditions and alter the expression of a number of genes including the cystic fibrosis transmembrane conductanc
Externí odkaz:
https://doaj.org/article/66a114df06784fe78b9a18e3ae4b3456
Autor:
Lianwu Fu, Andras Rab, Li ping Tang, Zsuzsa Bebok, Steven M Rowe, Rafal Bartoszewski, James F Collawn
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0123131 (2015)
The ΔF508 mutant form of the cystic fibrosis transmembrane conductance regulator (ΔF508 CFTR) that is normally degraded by the ER-associated degradative pathway can be rescued to the cell surface through low-temperature (27°C) culture or small mol
Externí odkaz:
https://doaj.org/article/c070ba713d724046b7dd64368bbb8178
Autor:
Yiming Zhang, Zsuzsa Bebok
Publikováno v:
Single Nucleotide Polymorphisms ISBN: 9783031056147
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a1317b81774db8739c48a5e571908b92
https://doi.org/10.1007/978-3-031-05616-1_6
https://doi.org/10.1007/978-3-031-05616-1_6
Autor:
Lianwu Fu, Zsuzsa Bebok
Publikováno v:
Endoplasmic Reticulum Stress in Diseases. 5:11-29
Cystic fibrosis (CF) is a life-shortening, genetic disorder caused by mutations in the cystic fibrosis transmembrane conductance regulator gene (CFTR). The primary cause of CF is reduced CFTR-mediated chloride and bicarbonate transport, due to mutati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1e87a84c870aa81714f6fe833a67dc5
https://doi.org/10.1515/ersc-2018-0002
https://doi.org/10.1515/ersc-2018-0002
Autor:
Wojciech Kamysz, James F. Collawn, Zsuzsa Bebok, Jarosław Króliczewski, Rafal Bartoszewski, Sylwia Bartoszewska, Marek Sanak, Bogdan Jakiela
Publikováno v:
Cellular & Molecular Biology Letters, Vol 22, Iss 1, Pp 1-14 (2017)
Cellular & Molecular Biology Letters
Cellular & Molecular Biology Letters
Background Hypoxic conditions induce the expression of hypoxia-inducible factors (HIFs) that allow cells to adapt to the changing conditions and alter the expression of a number of genes including the cystic fibrosis transmembrane conductance regulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdd696f217d7d992810cefe775047285
http://link.springer.com/article/10.1186/s11658-017-0054-0
http://link.springer.com/article/10.1186/s11658-017-0054-0
Autor:
James F. Collawn, Rafal Bartoszewski, David K. Crossman, Joseph W. Brewer, Niren Kapoor, Sylwia Bartoszewska, Zsuzsa Bebok, Catherine M. Fuller, Andras Rab
Publikováno v:
Journal of Biological Chemistry. 286:41862-41870
To identify endoplasmic reticulum (ER) stress-induced microRNAs (miRNA) that govern ER protein influx during the adaptive phase of unfolded protein response, we performed miRNA microarray profiling and analysis in human airway epithelial cells follow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f654e962c2eacdf1f244623fbc2f082
https://doi.org/10.1074/jbc.m111.304956
https://doi.org/10.1074/jbc.m111.304956
Autor:
Igor Nudelman, Marina Mazur, Steven M. Rowe, Erik M. Schwiebert, Valery Belakhov, Peter A. Sloane, David M. Bedwell, Jessica A. Buckley-Lanier, Kyle Backer, Li Ping Tang, Zsuzsa Bebok, Timor Baasov
Publikováno v:
Journal of Molecular Medicine. 89:1149-1161
Certain aminoglycosides are capable of inducing "translational readthrough" of premature termination codons (PTCs). However, toxicity and relative lack of efficacy deter treatment with clinically available aminoglycosides for genetic diseases caused
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c6049967db2b4aa4d22d364f01098cf
https://doi.org/10.1007/s00109-011-0787-6
https://doi.org/10.1007/s00109-011-0787-6
Publikováno v:
Expert Review of Proteomics. 7:495-506
Proteomic analysis has proved to be an important tool for understanding the complex nature of genetic disorders, such as cystic fibrosis (CF), by defining the cellular protein environment (proteome) associated with wild-type and mutant proteins. Prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f58440c5be992641a025f701ee18d4e6
https://doi.org/10.1586/epr.10.45
https://doi.org/10.1586/epr.10.45
Autor:
Rafal Bartoszewski, James F. Collawn, Sadis Matalon, Lan Chen, Asta Jurkuvenaite, Rebecca F. Goldstein, Zsuzsa Bebok
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 42:363-372
The most common mutation in the cystic fibrosis (CF) transmembrane conductance regulator (CFTR) gene, Delta F508, results in the production of a misfolded protein that is rapidly degraded. The mutant protein is temperature sensitive, and prior studie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d15bfb715f3ea59bf9810ff2cc2e5c5
https://doi.org/10.1165/rcmb.2008-0434oc
https://doi.org/10.1165/rcmb.2008-0434oc
Autor:
James A. Fortenberry, Zsuzsa Bebok, Arkadiusz Piotrowski, George B. Twitty, Lauren Stevenson, Rafal Bartoszewski, Jan P. Dumanski, Andras Rab
Publikováno v:
Journal of Biological Chemistry. 283:12154-12165
The unfolded protein response (UPR) aids cellular recovery by increasing the capacity and decreasing the protein load of the endoplasmic reticulum (ER). Although the main pathways of the UPR are known, the mechanisms of UPR-associated transcriptional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cc66694d8620c222153b54352c1f18f
https://doi.org/10.1074/jbc.m707610200
https://doi.org/10.1074/jbc.m707610200