Výsledky vyhledávání - "Zsuzsa, Hadady"

Akademický článek

C-(β-D-Glucopyranosyl) heterocycles as potential glycogen phosphorylase inhibitors

Publikováno v: ARKIVOC, Vol 2004, Iss 7, Pp 140-149 (2004)

Externí odkaz: https://doaj.org/article/a60cd757e1f645eb8015acd7d5093f01

Kinetic and crystallographic studies on 2-( -D-glucopyranosyl)-5-methyl-1, 3, 4-oxadiazole, -benzothiazole, and -benzimidazole, inhibitors of muscle glycogen phosphorylase b. Evidence for a new binding site

Autor: Rozina Kardakaris, László Somsák, Tibor Docsa, Evangelia D. Chrysina, Nikos G. Oikonomakos, Nicolas Bischler, Magda Kosmopoulou, Zsuzsa Hadady, Pál Gergely, Constantinos Tiraidis, Demetres D. Leonidas

Publikováno v: Protein Science. 14:873-888

Glycogen phosphorylase (GP), because of its central role in glycogen metabolism, has been exploited as a potential target for structure-based design of potent inhibitors, that may be relevant to the control of blood glucose concentrations in type 2 d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7a4eeee38464f3f24a01eabbfef357c
https://doi.org/10.1110/ps.041216105

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C-(β-D-Glucopyranosyl) heterocycles as potential glycogen phosphorylase inhibitors

Autor: László Somsák, Marietta Tóth, Zsuzsa Hadady

Publikováno v: ARKIVOC, Vol 2004, Iss 7, Pp 140-149 (2004)

Per-O-acetylated and -benzoylated β-D-glucopyranosyl cyanides were transformed into the corresponding 5-( β-D-Glucopyranosyl)tetrazoles, 2-( β-D-glucopyranosyl)benzothiazoles, and, via the benzoylated C-( β-D-glucopyranosyl) ethyl thioformimidate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3db904f17dd82bb714e6233f65c45484
https://doi.org/10.3998/ark.5550190.0005.711

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Synthesis of N-(beta-D-glucopyranosyl) monoamides of dicarboxylic acids as potential inhibitors of glycogen phosphorylase

Autor: Zsuzsa Hadady, Pál Gergely, Jürgen Schmidt, Tibor Docsa, Katalin Czifrák, Ludger A. Wessjohann, László Somsák

Publikováno v: Carbohydrate research. 341(8)

O-peracetylated N-(beta-D-glucopyranosyl)imino trimethylphosphorane obtained in situ from 2,3,4,6-tetra-O-acetyl-beta-D-glucopyranosyl azide and PMe3 was reacted with saturated and unsaturated aliphatic and aromatic dicarboxylic acids, or their anhyd

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d169672b269573c38caca270c1094666
https://pubmed.ncbi.nlm.nih.gov/16564511

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Synthesis of N-(beta-D-glucopyranosyl)- and N-(2-acetamido-2-deoxy-beta-D-glucopyranosyl) amides as inhibitors of glycogen phosphorylase

Autor: Attila Brunyanszki, Zoltán Györgydeák, Tibor Docsa, Veronika Nagy, László Somsák, Marietta Tóth, Attila Krakomperger, Zsuzsa Hadady, Pál Gergely, Nóra Felföldi

2,3,4,6-Tetra- O -acetyl-β- D -glucopyranosyl- and 2-acetamido-3,4,6-tri- O -acetyl-2-deoxy-β- D -glucopyranosyl azides were transformed into the corresponding per- O -acetylated N -(β- D -glycopyranosyl) amides via a PMe 3 mediated Staudinger pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::127965080da633b5af8fff05450afea9

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Glucose analog inhibitors of glycogen phosphorylases as potential antidiabetic agents: recent developments

Autor: László Somsák, Tibor Docsa, Veronika Nagy, Zsuzsa Hadady, Pál Gergely

Diabetes is among the largest contributors to global mortality through its long term complications. The worldwide epidemic of type 2 diabetes has been stimulating the quest for new concepts and targets for the treatment of this incurable disease. A n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc7e478277e0d00431b3f4d22cc8b662

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