Zobrazeno 1 - 10
of 136
pro vyhledávání: '"Zsolt Szakonyi"'
Autor:
Márton Benedek Háznagy, Antal Csámpai, Imre Ugrai, Barnabás Molnár, Matti Haukka, Zsolt Szakonyi
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 8, p 4325 (2024)
A library of regioisomeric monoterpene-based aminodiols was synthesised and applied as chiral catalysts in the addition of diethylzinc to benzaldehyde. The synthesis of the first type of aminodiols was achieved starting from (−)-8,9-dihydroperillal
Externí odkaz:
https://doaj.org/article/9a5776cb88fa4fea8d9d65fd187e88f8
Publikováno v:
Pharmaceuticals, Vol 17, Iss 2, p 262 (2024)
Starting from isosteviol, a series of diterpenoid 1,3-aminoalcohol derivatives were prepared via stereoselective transformations. The acid-catalysed hydrolysis and rearrangement of natural stevioside produced isosteviol, which was transformed into th
Externí odkaz:
https://doaj.org/article/ceba688d29ac494b806099d0ba6fd7ee
Publikováno v:
Molecules, Vol 28, Iss 24, p 7962 (2023)
A series of novel diterpene-type 1,3-aminoalcohols and their regioisomers have been synthesised from natural stevioside in a stereoselective manner. The key intermediate β-keto alcohol was prepared using Wagner–Meerwein rearrangement of the epoxid
Externí odkaz:
https://doaj.org/article/6a78e1330c9a4d4f8da727b2d2e509f3
Autor:
Eszter Bokor, Judit Ámon, Mónika Varga, András Szekeres, Zsófia Hegedűs, Tamás Jakusch, Zsolt Szakonyi, Michel Flipphi, Csaba Vágvölgyi, Attila Gácser, Claudio Scazzocchio, Zsuzsanna Hamari
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-11 (2022)
A novel nicotinate degradation pathway is described in Aspergillus nidulans, with metabolic products identified that were not previously found in prokaryotic species. This is the first such pathway to be described in a eukaryote.
Externí odkaz:
https://doaj.org/article/9e9ab06af27f41c9be825dfd21fdd68a
Autor:
Viktória Nagy, Raji Mounir, Gábor J. Szebeni, Zsolt Szakonyi, Nikolett Gémes, Renáta Minorics, Péter Germán, István Zupkó
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 13, p 10581 (2023)
The present study aimed to characterize the antiproliferative and antimetastatic properties of two recently synthesized monoterpene-aminopyrimidine hybrids (1 and 2) on A2780 ovary cancer cells. Both agents exerted a more pronounced cell growth inhib
Externí odkaz:
https://doaj.org/article/3543d74e3e7647bb811aea7228bb4dd0
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 17, Iss 1, Pp 983-990 (2021)
A library of pinane-based 2-amino-1,3-diols was synthesised in a stereoselective manner. Isopinocarveol prepared from (−)-α-pinene was converted into condensed oxazolidin-2-one in two steps by carbamate formation followed by a stereoselective amin
Externí odkaz:
https://doaj.org/article/e2d8a6aea0074704bf2fd70136504dd2
Autor:
Dorottya Bai, Zsuzsanna Schelz, Dóra Erdős, Anna K. Kis, Viktória Nagy, István Zupkó, György T. Balogh, Zsolt Szakonyi
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 2, p 1121 (2023)
A new family of diterpene-type aminotriol derivatives has been synthesised from stevioside in a stereoselective manner. The key intermediate spiro-epoxide was prepared through the methyl ester of the allilyc diol derived from steviol. The oxirane rin
Externí odkaz:
https://doaj.org/article/d8d9ebad6dc04716a5a2912180065f94
Publikováno v:
Catalysts, Vol 12, Iss 9, p 992 (2022)
Asymmetric Michael additions of carbonyl compounds to N-substituted maleimides are among the most convenient reactions to prepare optically pure succinimide building blocks. Although a few β-amino acids were found to be highly efficient organocataly
Externí odkaz:
https://doaj.org/article/2ca223a802144f7190dd32b3bcd9a485
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 18, p 10366 (2022)
A series of gibberellic acid-based aminodiols was designed and synthesized from commercially available gibberellic acid. Exposure of gibberellic acid to hydrochloric acid under reflux conditions resulted in aromatization followed by rearrangement to
Externí odkaz:
https://doaj.org/article/68852f3bbac44adcbd302b36cd550187
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 20, p 11232 (2021)
Starting from isosteviol, a series of diterpenoid 1,3-aminoalcohol derivatives were stereoselectively synthesised. The acid-catalysed hydrolysis and rearrangement of natural stevioside gave isosteviol, which was transformed to the key intermediate me
Externí odkaz:
https://doaj.org/article/6c6eba07cb74496b86f8e76ac157381b